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favela808 1896 posts  |  Last Activity: Apr 16, 2015 8:44 AM Member since: Jan 23, 2003
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  • Reply to

    neuropathic pain

    by andy55q Apr 15, 2015 9:19 AM
    favela808 favela808 Apr 16, 2015 8:44 AM Flag

    Another pain drug. You could double the efficacy and cut the side effects in half and you still don't compare to Calmare which has 80% efficacy and NO SIDE EFFECTS!


  • I'm amazed how far the stock went up today on something that was exciting only for the industry not specif to PTN. This is a hot topic and Maybe CTTC is next. They have a better formula than PTN. PTN got there license from CTTC.

  • Calmare Therapeutics to Present at the LD Micro "Main Event" Microcap Growth Conference

    Fairfield, CT / ACCESSWIRE / December 3, 2014 / Calmare Therapeutics Incorporated, (CTTC) (CTI), the pain mitigation company, will present at the 7th Annual LD Micro "Main Event" Micro-Cap Growth Conference on Thursday, December 4 at 7:30 AM PT/10:30 AM EST. The conference will be held at the Luxe Sunset Bel Air Hotel, in Los Angeles, California.

    Calmare Therapeutics President & CEO Conrad Mir will present. He is slated to provide an update on the Company's business development and the ongoing plan to maximize their signature technology, Calmare Pain Mitigation Therapy(TM). Mr. Mir will be available for one-on-one meetings during the conference.

    "We are honored to have Calmare Therapeutics present at the Main Event this year," said LD Micro Founder Chris Lahiji.

    About LD MICRO

    LD Micro is an investment newsletter firm that focuses on finding undervalued companies in the micro-cap space. Since 2002, the firm has published reports on select companies throughout the year. The firm also hosts the LD Micro Invitational. It is a non-registered investment advisor. For more information, please contact 408-457-1042 or visit

  • life-changing treatment option
    Nov 18, 2014 | Kyle Valentine, DMD | Portland , OR
    Client's rating: 5 of 5
    I experienced the onset of muscle and nerve pain in my neck and back, made worse by long hours working as a general dentist. Eventually, my condition became so severe that I could no longer practice clinical dentistry. It became extremely discouraging to spend a great deal of money and valuable time on treatments and doctor visits hoping to find something to alleviate the pain. As a last resort, several expensive surgical options were recommended with less than ideal success rates. Fortunately, before I committed to surgery, my family physician recommended I treatment offered at Radiant Pain Relief Centres. I was cautiously optimistic after years of failed treatment, but I was offered a FREE initial treatment to see if the type of pain I experienced could be treated with the Radiant Pain Relief Centre’s technology. I loved the opportunity to try the treatment before investing additional time and money. The process was actually relaxing and best of all, I experienced 100%, true pain relief before the end of my first free treatment. My experience with the Calmare treatment was unique in that I finally experienced successful, sustained pain relief, allowing me to return to my day-to-day responsibilities. This was a game changer for me. I was able to avoid risky and expensive surgery, narcotic painkillers and weeks of recovery from a costly surgical procedure without knowing the outcome. It was an easy decision after experiencing a successful free treatment and one of the best decisions I've ever made. My sincere praise for the life-changing treatment option is given with complete confidence. My only regret is that I didn't have the opportunity to receive treatment five years ago, but then I may not have appreciated how incredible a simple, non-invasive treatment option could provide such profound success. It was definitely an experience unlike any other.

    Sentiment: Strong Buy

  • favela808 favela808 Nov 17, 2014 1:01 PM Flag

    That was the case with Karen - the pain was so severe she could barely walk.

    When she heard about the clinical trial at the Mayo, she signed up right away.

    Dr. Loprinzi says the Scrambler, which looks like a large car battery, is designed to break the pain cycle...

    SOT - Dr. Charles Loprinzi
    "You put electrodes on those nerves and you give them different electrical signals - and those different electrical signals kind of retrain the brain and say: 'Really, this isn't pain.'" (:08)

    That's easy for him to say - but she says it, too.

    The Scrambler therapy started working after the very first treatment - and after four treatments, the pain she had endured for more than a decade was gone...

    SOT - Karen Safranek
    "It was so incredible that I hadn't felt pain-free for so many years that I guess I didn't expect it to last..." (:10)

    But it's been a year now, and Karen is still pain-free.

    The Osgood File. Charles Osgood on the CBS Radio Network.



    The Osgood File. Sponsored in part by Kyocera. Intelligent printers and MFPs, customized apps and services to make your whole business more productive. Total Document Solutions Only From Kyocera. This is Charles Osgood.

    Sometimes, cancer patients treated with chemotherapy suffer severe and chronic pain that doesn't go away - even if the treatment succeeds and the cancer does go away.

    That's what happened to Karen Safranek...

    SOT - Karen Safranek, breast cancer survivor
    "On a scale of 1 to 10, it was like a 12. It was excruciating pain - like my feet and my legs were on fire. It's so hard to describe, because they felt so painful - yet they were numb." (:13)

    Enter a machine called "The Scrambler" now being tested at the Mayo Clinic.

    We'll tell you about it after this...

    ((( BREAK )))

    The awful pain that breast cancer patient Karen Safranek suffered for years was caused by something called "peripheral neuropathy," says Dr. Charles Loprinzi of the Mayo Clinic...

    SOT - Dr. Charles Loprinzi, Mayo Clinic
    "It's a major problem from a number of chemotherapy drugs, probably the most prominent problem that we have these days. For some, it limits how much chemotherapy we can give. For some that get the chemotherapy, it gets better afterwards - but it stays there and can be a persistent problem for years." (:14)

    That was the case with Karen - the pain was so severe she could barely walk.

    When she heard about the clinical trial at the Mayo, she signed up right away.

    Dr. Loprinzi says the Scrambler, which looks like a large car battery, is designed to break the pain cycle...

    SOT - Dr. Charles Loprinzi
    "You put electrodes on those nerves and you give them different electrical signals - and those different electrical signals kind of retrain the brain and say: 'Really, this isn't

  • Reply to

    Oops! There went Southridge Partners!

    by succhiacazzo Nov 14, 2014 10:52 AM
    favela808 favela808 Nov 17, 2014 12:54 PM Flag

    That's good news. the Southridge deal as you know stunk.Why would we want to do that? Old management put that deal together. That's why they are gone. Stupidest deal ever. This is great news! The new CEO is putting together much better deals.

  • Reply to

    Mayo Clinic has a new Video on Calmare

    by favela808 Oct 13, 2014 12:07 AM
    favela808 favela808 Oct 21, 2014 2:07 AM Flag

    They are doing research. They don't offer it clinically yet. When that time comes I'm sure they will buy many machines.

    Sentiment: Strong Buy

  • Mayo Clinic in the News Weekly Highlights

    By Karl W Oestreich

    Mayo Clinic in the News LogoMayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note to Laura Wuotila with this subject line: SUBSCRIBE to Mayo Clinic in the News.

    Thank you.

    Karl Oestreich, manager enterprise media relations

    Reuters TVScrambling away pain for cancer patients

    Researchers are testing a device called the Scrambler which ''re-trains'' the brain to alleviate chronic pain caused by chemotherapy Reuters VIdeo logotreatment… Dr. Charles Loprinzi of the Mayo Clinic says peripheral neuropathy occurs when the brain sends pain signals to damaged nerves in a constant cycle.

  • favela808 by favela808 Oct 13, 2014 12:01 AM Flag

    Sentiment: Strong Buy

  • Abstract:

    Background: More effective treatment is needed for chemotherapy-induced peripheral neuropathy (CIPN). Preliminary data support the use of Scrambler therapy, a device which treats pain via non-invasive cutaneous electrostimulation, for the treatment of CIPN (Smith TJ et al. J Pain Symptom Manage 2010). The current abstract reports data from a pilot trial, performed to investigate the effect of Scrambler therapy for the treatment of established CIPN. Methods: Eligible patients: age ≥ 18 years, ECOG PS ≤2, life expectancy ≥3 months, CIPN symptoms of ≥1 month duration with tingling and/or pain ≥4/10 during the prior week. Patients were treated with Scrambler therapy to the affected area(s) for up to 10 daily 30 minute sessions. Symptoms were monitored using a neuropathy questionnaire consisting of numerical analogue scales ranging from 0-10, daily before therapy as well as weekly for 10 weeks after therapy. Descriptive summary statistics formed the basis of data analysis. During the daily therapy, last values carried forward were used. Results: We report on 37 patients enrolled between 7/18/2011 and 5/6/2013, 12 men and 25 women; the mean age was 58. While the study technically remains open to obtain more experience with this procedure, the first 37 accrued CIPN patients are the basis of our final CIPN-related manuscript from this project (in development). Patients had a history of exposure to various neurotoxic chemotherapeutic agents and the majority (78%) had symptoms ≥1 year. 25 patients were treated primarily on their lower extremities while 12 were treated primarily on their upper extremities. The table portrays data (average symptoms during the previous 24 hours) at baseline, on the last of the 10 planned days of therapy, and at the end of 10 weeks of follow up, regarding patient reported pain, tingling, and numbness. There were no substantial adverse events. Conclusions: Scrambler therapy appears to be effective for the treatment of CIPN:

    Sentiment: Strong Buy

  • Competitive Tech to Host Private Engagement for Top Opinion Leaders at the ASCO 2014 Annual Meeting
    Guest Speakers to Discuss Calmare® Pain Device Therapy Treatment; Company Developed Medical Milestones and Advancements to be Disclosed
    Conference: May 30 - June 3, 2014 | The McCormick Center, Chicago, IL | Booth 5072
    Private Engagement: June 1, 2014 | Hyatt Regency McCormick Place, Chicago, IL
    PR Newswire Competitive Technologies, Inc.
    21 hours ago
    FAIRFIELD, Conn., May 6, 2014 /PRNewswire/ -- Competitive Technologies, Inc., (CTI), the pain mitigation company, will host a private engagement for top opinion leaders in oncology at the Hyatt Regency McCormick Place on June 1, 2014 during the 50th Annual American Society of Clinical Oncology (ASCO) in Chicago, IL.

    At the private engagement, there will be a morning panel discussion on the treatment of chemotherapy-induced peripheral neuropathy (CIPN) using Calmare Pain Device Therapy. The panel will consist of Dr. Thomas J. Smith from the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Medicine and Dr. Charles L. Loprinzi, Regis Professor of Breast Cancer Research, Division of Medical Oncology at the Mayo Clinic.

    CTI will exhibit and feature their signature device, the Calmare Pain Device, at Booth 5072 at the McCormick Center during ASCO.

    "ASCO 50th annual meeting is the perfect venue to introduce Calmare to the world's top opinion leaders," commented CTI President & CEO Conrad Mir. "We feel Calmare therapy may be the alternative therapy that alternative therapy that patients, plagued with chronic pain, need in order to return to a pain-free lifestyle. As a medical device Company furthering such an innovative product, it is important that the medical community is made aware of this non-invasive approach that may revolutionize the way pain is managed."

    Sentiment: Strong Buy

  • Scrambler Therapy in the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy
    This study is not yet open for participant recruitment.
    Verified April 2014 by Sidney Kimmel Comprehensive Cancer Center
    Sidney Kimmel Comprehensive Cancer Center
    Information provided by (Responsible Party):
    Sidney Kimmel Comprehensive Cancer Center Identifier:
    First received: March 23, 2014
    Last updated: April 8, 2014
    Last verified: April 2014
    History of Changes
    Full Text View Tabular ViewNo Study Results PostedDisclaimerHow to Read a Study Record
    The purpose of this study is to see if Scrambler Therapy with the Calmare MC5-A machine will relieve chemotherapy induced peripheral neuropathy (CIPN).

    Scrambler Therapy is a method of pain relief given with common electrocardiography (ECG) skin electrodes. The electrodes are placed on the body in pairs, and the Scrambler Therapy machine directs electrical signals across the field to simulate non-pain information.

    Based on other studies, we think that we relieve pain with the Scrambler therapy device, but it has not been tested in a setting such as this one. This means that some of the pain relief could be due to placebo effect, or the CIPN pain going away on its own. In this study we want to compare the Scrambler Therapy with the sham therapy (the therapy that does not use the electrical signals). We hope that this study will help us determine if the Scrambler device really helps patients with CIPN.

    Cancer patients with chronic, chemotherapy-related pain of 4 or more (on a 0-10 scale) for at least 3 months may be eligible to join this study.

    Sentiment: Strong Buy

  • Competitive Technologies (NASDAQ:CTTC)‘s stock had its “neutral” rating reiterated by Zacks in a research report issued to clients and investors on Wednesday, ARN reports. They currently have a $0.50 target price on the stock. Zacks‘s price target would indicate a potential upside of 61.29% from the company’s current price.
    Zacks’ analyst wrote, “Competitive Technologies’ current main focus lies with the marketing and distribution of the FDA-cleared and CE Marked Calmare pain therapy device. While several small studies provide some support of its efficacy, lack of broad reimbursement from private and public payers has been a significant headwind in accelerating commercialization of Calmare. A new CEO was brought onboard to orchestrate a turnaround which includes the plan to run two pivotal clinical studies to support an FDA PMA submission and improved reimbursement status. A near-term initiative to spark a resurgence in revenue growth includes streamlining the process to sell to U.S. government entities. While we think the new commercialization strategy makes sense, an investment in CTI is not without meaningful risk which is factored into our investment rating. We are initiating coverage of CTI with a Neutral rating and $0.50/share price target. “
    Competitive Technologies (NASDAQ:CTTC) traded up 10.67% during mid-day trading on Wednesday, hitting $0.31. 23,150 shares of the company’s stock traded hands. Competitive Technologies has a 52 week low of $0.05 and a 52 week high of $0.48. The stock’s 50-day moving average is $0.29 and its 200-day moving average is $0.25. The company’s market cap is $5.9 million.

    Sentiment: Strong Buy

  • Reply to

    Pain Article

    by favela808 Feb 25, 2014 10:37 AM
    favela808 favela808 Feb 25, 2014 10:43 AM Flag

    At first, these new nerve impulses going through my central nervous system felt a bit like a bee sting or a strange vibration. But after a minute or two, the only thing I noticed was the pain receding. Even though my pain came back after a few hours that first day, it reminded me what having a normal, pain-free life was like, something I wouldn’t have thought possible.

    For the first time in months, I was able to sit with my legs down in a chair — not balled up close to my body to keep them from swelling painfully. When I touched my typically oversensitive skin, it also felt different. I could feel the skin and the muscles in my legs again. It felt so weird. Good weird.

    When I left the clinic after that first day of treatment, everyone in the room got hugs. I had never hugged a doctor before.

    When I got home, I was able to take a nap for the first time in weeks. I actually fell asleep in a chair while reading because I felt so good.

    I was really skeptical when I first heard about Calmare because I know things like TENS and spinal cord stimulators don’t work for me. I was really apprehensive, but I am so glad that I tried it and that is working.

    The pain that I still experience daily is different from the pain I had a week ago. I am only halfway through my treatment and it is amazing! Compared to everything else I have tried, this is working wonders. I have pain-free times every day. Each day I walked into the clinic with less and less pain and walked out pain-free.

    I have actually been able to get out of the house! I went to the mall and walked around, took my dog on a long walk, and took my family to a water park. It has been a life changer!

    I’m super excited to see where the rest of the treatment takes me. I am hopeful that this treatment may allow my husband and I to finally start planning on having another baby, which was something we never thought possible because of my CRPS.

  • Reply to

    Pain Article

    by favela808 Feb 25, 2014 10:37 AM
    favela808 favela808 Feb 25, 2014 10:40 AM Flag

    ’ve only been walking since I attended the Rehabilitation Institute of Washington’s CRPS program in Seattle in November of last year, which got me out of a wheelchair and back on my feet. That was certainly a change for the better, but my quality of life was still nowhere near what I wanted it to be. A 4-5 on the 10 pain scale had become my “tolerable normal” and what I was beginning to anticipate for the rest of my life.

    image (2)The thing about Calmare that boggles my mind is that after trying all manner of painful procedures and medicines, and waiting weeks or months to see a result — if you have the type of pain that Calmare therapy treats, you’ll know if it will be successful for you within a few minutes.

    My first day of therapy, I walked in at a 6/10, and left an hour later, eerily close to pain-free. I started feeling a change in 30 minutes.

    The pain in my legs started to creep back in after a few hours, but I’m told that is typical after one treatment.

    Patients typically go for 10 consecutive days of Calmare treatment, though each case is different. By the end of that first round of treatment, the objective is that patients be pain-free for 30-90 days. At that point a booster treatment of one or two sessions will keep you going for another 30-90 days free of pain. It’s repeatable, not something your body is going to develop a resistance to the same way it might with drugs.

    The treatment itself is nothing more than being hooked by a few electrodes up to a machine. Electrodes placed, I might add, well outside of any area affected by pain.

    I like to think that Calmare works for pain much the same way that noise-canceling headphones do for ambient noise. The Calmare machine interrupts the chronic pain signals your brain is used to receiving and replaces those distorted nerve signals with a normal, pain-free sensation.

  • Reply to

    Pain Article

    by favela808 Feb 25, 2014 10:37 AM
    favela808 favela808 Feb 25, 2014 10:38 AM Flag

    Calmare uses electricity to block pain signals without the use of drugs. Originally developed for people suffering from chemotherapy induced peripheral neuropathy, Calmare has also been found to be and effective at treating other types of neuropathic pain, including Complex Regional Pain Syndrome (CRPS), which I’ve suffered from over the last two years.

    Calmare won’t treat mechanical pain, however. Mechanical pain in my case being the collapsed arch in my foot and the sprained ankle that led to my CRPS in the first place.

    Having the pain from my CRPS gone is like listening to the sounds of the forest, after being in an office building next to jackhammers and construction all day. The volume is turned down and suddenly you’re receiving far less sensory input. You are able to notice much more subtle nuanced things that you never had the capacity, energy or space to notice before.

    I can feel sore muscles in my foot again. I can feel them because my feet hurt so much and were so hypersensitive to touch and pressure that I wasn’t able to walk normally on them for nearly two years. My leg and foot muscles atrophied so much I had to retrain myself to walk with proper form.

  • favela808 by favela808 Feb 25, 2014 10:37 AM Flag

    National Pain Report

    Life in Pain: How Calmare Therapy Helped Me

    February 24th, 2014 by Amanda Siebe, Columnist
    Living with pain every day is kind of like living next to an airport. After a while you don’t hear the jets flying overhead anymore. They’re still there, in the middle of the night and the middle of the day, unending and ceaseless, but you don’t notice every time one flies over.

    Chronic pain is much the same. After you’ve had it long enough, your body accepts that sensation as normal. You no longer expect pleasant sensations from touch. You don’t expect to be able to wear normal clothes or take a shower. You don’t expect to be able to exercise muscles in that part of your body without excruciating pain.

    Occasionally, however, something happens that makes you reconsider everything that you’ve come to expect. Something happens that gives you a new normal.

    I started Calmare therapy last week at Pain Relief of Oregon in West Linn, OR.

    Most of my pain has gone away.

  • Reply to

    Medicare News

    by favela808 Jan 15, 2014 10:52 AM
    favela808 favela808 Feb 2, 2014 12:56 AM Flag

    January 31, 2014 by Chris Walker

    Competitive Technologies wins a favorable Medicare coverage decision for its Calmare device, with labeling as a "medical necessity."

    Competitive Technologies lands Medicare coverage for pain management device
    Competitive Technologies said it secured a favorable decision concerning Medicare coverage for its Calmare pain management device.

    The Fairfield, Conn.-based medical device company develops products for wound and pain management. The Calmare is the company's flagship product, and is used to treat neurological pain.

    The Medicare decision allows for the device to be covered as a "medical necessity" in cancer-related chemotherapy treatment. The reimbursements will go to the Calmare Pain Relief Solutions, which developed the technology.

86.46+1.23(+1.44%)Aug 26 4:00 PMEDT