They write influential articles to sway their trading positions in their favor.
What if a drugmaker spent billions of dollars to create a vaccine -- only to find out humans developed natural resistance to the disease before its product is ready?
That is part of the scenario GlaxoSmithKline Plc and other pharmaceutical giants are weighing in their cautious approach to developing a Zika vaccine.
Large portions of the populations in Zika-affected areas could develop immunity to the virus over the next five to 10 years, slowing its circulation into virgin areas, said Moncef Slaoui, chairman of London-based Glaxo’s vaccines division. That would make it harder to determine the market for a vaccine, which could be just stockpiled for outbreaks rather than used widely during national immunization campaigns.
Although fear of the virus remains high in the U.S. and its territories -- where almost 300 pregnant women have shown signs of possible infection, according to the Centers for Disease Control and Prevention -- lawmakers are pushing back on funding to fight it. Glaxo, Merck & Co. and Johnson & Johnson are all moving slowly, in contrast with their reaction to Ebola two years ago, when the drugmakers doubled down on developing a vaccine before their efforts stalled as the outbreak in West Africa waned.
“The notion is not that there is no need for a vaccine” for Zika, Slaoui said. “What’s not predictable is how to use this vaccine.”
The World Health Organization declared Zika a public health emergency in February and began an emergency research and development plan for tests, vaccines and drugs. While Ebola is a deadly virus that killed more than 10,000 people in the latest outbreak, Zika doesn’t cause serious illness in most infected people. Zika is a major threat mainly to pregnant women, as it can trigger severe birth defects, and is also linked to an increase in cases of a rare neurological disorder.
“While Zika has a high potential impact on women of reproductive age, its limited effect on general health could easily see fu
In a paper published today in the journal Nature, a research team led by scientists at Beth Israel Deaconess Medical Center (BIDMC), in collaboration with scientists at Walter Reed Army Institute of Research (WRAIR) and the University of Sao Paulo, demonstrates that two different ZIKV vaccine candidates provided complete protection in mice against a ZIKV strain from Brazil and suggest that a ZIKV vaccine for humans will likely be feasible.
ZIKV is a member of the flavivirus family of viruses. Transmitted by mosquitoes, ZIKV is responsible for an unprecedented epidemic in the Americas. This family of viruses also includes West Nile virus, yellow fever virus, Japanese encephalitis virus, tick-borne encephalitis virus, and dengue viruses, for which successful vaccines have been developed.
"Our data demonstrate that a single dose of a DNA vaccine or a purified inactivated virus vaccine provides complete protection against the ZIKV challenge in mice," said senior author Dan H. Barouch, MD, PhD, Director of the Center for Virology and Vaccine Research at BIDMC, Professor of Medicine at Harvard Medical School, and Steering Committee member at the Ragon Institute of MGH, MIT and Harvard. "Importantly, we showed that vaccine-induced antibodies provided protection, similar to existing vaccines for other flaviviruses."
I believe it is, at the present time. Over the next six months they will have to demonstrate progress with their recent integrations and expanded product lines. If they do that, we will see a nice bounce.
Uptrend still intact.
on price and performance. Rapid sales growth is his game.
Why aren't you buying at these bargain basement prices?
They needed to finance it quickly to close ASAP.
Pursuant to the Underwriting Agreement, directors and executive officers of the Company entered into agreements in substantially the form included as an exhibit to the Underwriting Agreement providing for a 90-day "lock-up" period following the date of the final prospectus supplement with respect to sales of specified securities, subject to certain exceptions including
waiting for the shakeout and then.
I am surprised by the low offering price. I do agree they wanted this done quickly, for a reason. We should here about the acquisition soon after the closing of the financing. I bet it will be oversubscribed. The underwriters know what is coming, even if we don't.