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Penn Virginia Corporation Message Board

me2yousee 603 posts  |  Last Activity: Sep 23, 2016 6:47 AM Member since: Feb 25, 2012
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  • me2yousee me2yousee Sep 23, 2016 6:47 AM Flag

    I understand. My point is that as body efficiency is lost, it may take an ever increasing dosage to produce the same results. Most testing of everything to this point has been with a fixed dosage. So essentially, everything is doomed to produce decreasing stats.

    Sentiment: Strong Buy

  • me2yousee me2yousee Sep 22, 2016 10:26 PM Flag

    The problem with curing anything with the aged is that nothing is a fountain of youth to go along with the attempt. This is what is always over looked particularly with AD. Delaying in itself is a God send.

    Sentiment: Strong Buy

  • Reply to

    addiction on the rise

    by cladybugm Aug 19, 2016 2:52 PM
    me2yousee me2yousee Aug 19, 2016 3:03 PM Flag

    Seems to me that something that doesn't rely on the patient will result in FAR greater success in treatment. May take awhile to catch on, because doctors love the $ from patient contact, but cost savings will have insurance companies in their corner.

    Sentiment: Strong Buy

  • Reply to

    Problems for the data...

    by envy_vo Jul 28, 2016 7:45 PM
    me2yousee me2yousee Jul 28, 2016 9:19 PM Flag

    Never been around Alheizmers patients huh? The bulk of AD patients don't have anything wrong with them if you ask them. Everyone that gets a little old has SOME memory problems, that's all.

    So patients aren't in the test because they are happy or even want to be. If you thought nothing was wrong with you, would you want to be prodded and tested all day long for months on end? That 's what makes AD patients tough to treat. Their families pushed them in because they weren't able to judge. Those that leave might not have been depressed at all and simply got tired and became unruly enough to make measurements inaccurate or impossible to administer. Or they could have had family issues. Or any number of reasons.

    So in fact, the most depressed would be the most easily controlled and unemotional and they stayed in the test.

    Sentiment: Strong Buy

  • Reply to

    Remember Management Extremely Conservative Now

    by me2yousee Jul 28, 2016 6:20 AM
    me2yousee me2yousee Jul 28, 2016 6:25 AM Flag

    Another point is that AAIC reviewed this data and considered it presentation quality as progress. The BOD rewarded Missling because THEY were pleased with his progress. The statement does include responses from notable researchers that still wish to be associated with 2-73 even with the mundane release.

    So are we getting the whole story?

    Sentiment: Strong Buy

  • That release was written to sound depressing and defendable in court. Question is, was any data eliminated to prevent the appearance of exuberance that would increase speculation?

    After last fall and the SEC probe and subsequent law suit, a Lawyer was hired that I am sure limited diction on the release to be as conservative as the write up sounds. Need proof? Just look / listen at the last conference presentation how Missling had to check off before he responded to anything without saying much at all.

    I expect future PRs will continue to disappoint. I don't like it, but that's just the way it's going to be.

    Sentiment: Strong Buy

  • People here don't understand Alheizmers and just how it affects patients that THINK they are and want to be in charge of themselves and independent. They expect some memory loss due to age. An alcoholic doesn't know he is one.

    What got me excited here was that family and caregivers saw the difference and asked for them to remain in the test. So measuring progress may be more difficult than we / I thought.

    Sentiment: Strong Buy

  • Reply to

    disappointed

    by holly2422 Jul 27, 2016 6:47 PM
    me2yousee me2yousee Jul 27, 2016 6:55 PM Flag

    Read the release again when you aren't depressed. It says, the improvement that they experienced leveled off. Not that they regressed. This test lasted as long as I'd has BECAUSE patients kept improving. Read my hand holding post.

    Sentiment: Strong Buy

  • Reply to

    Hand Holding From a Common Sense Perspective

    by me2yousee Jul 27, 2016 5:50 PM
    me2yousee me2yousee Jul 27, 2016 6:26 PM Flag

    Sorry, it's 3-71, not 3-73.

    Sentiment: Strong Buy

  • Reply to

    Hand Holding From a Common Sense Perspective

    by me2yousee Jul 27, 2016 5:50 PM
    me2yousee me2yousee Jul 27, 2016 6:14 PM Flag

    AVXL / Missling said it not me. 2-73 was for mild to moderate. 3-73 was for severe cases, ala a bigger hammer.

    Sentiment: Strong Buy

  • Never let stock price determine your logic. Stock price aside, this was GREAT news for me.

    1. We found out that we still have a portfolio of AD drugs. We don't have to throw 1-71 and 3-73 away because 2-73 does it all.

    2. Every one was complaining we weren't getting data that it was late. This was because it was still getting better. NOW we have an END date. A phase III, which HAD to happen anyway, can go for 2 or 3 months and END with data good enough for passage. MUCH cheaper than treating 200 patients for a whole year like this test.

    3. Still the best AD drug on earth, 2-73 doesn't cure. Patients must either remain on 2-73 for life OR move up to a bigger hammer like 3-73. Much BETTER income stream.

    Anybody looking at this from a common sense standpoint realizes their company will be worth MORE tomorrow because of these points. For the stock action / price, go get a drink. The problem here is too many wispy washy people that cut and run at the first sign of a bear raid. Oh well, somebody bought the stock today just as they will tomorrow. Maybe they won't be easily swayed.

    Sentiment: Strong Buy

  • Reply to

    disappointing

    by bourbon_on_my_cornflakes Jul 27, 2016 3:11 PM
    me2yousee me2yousee Jul 27, 2016 4:24 PM Flag

    That's NOT what caused the damage. In fact, patients plateauing means life time customers. What did it was needing another study which means continued dilution.

    Sentiment: Strong Buy

  • Wow, so much fuel, we are going to need another booster. People and hedges lookin at the chart and no news plus the low volume and misinterpreting the signs.

    Sentiment: Strong Buy

  • Compare open interest for August and September and check the premiums for August. Seems like a lot of protection was laid on but only for rapid action and then ppppffffttttt.

    Bottom line is to be careful and avoid margin here if it starts to run because it looks like the $7.50s for August 19th close. Margin does more rapid damage than shorts do.

    Sentiment: Strong Buy

  • me2yousee me2yousee Jul 26, 2016 9:17 AM Flag

    The only question with AVXL is, will it work on people other than Austrailians. :)

    Sentiment: Strong Buy

  • me2yousee me2yousee Jul 26, 2016 9:14 AM Flag

    To put your mind at ease, with AD treatments, you can connect machines to tell you something works. The only thing you have to test for is safety. Can't do that with everything else.

    Sentiment: Strong Buy

  • Be kind as they are the stones we walk on now. Then call NASA and report the launch.

    Shorts covering at a good clip in the pre market. Burn baby burn.

    Sentiment: Strong Buy

  • And there is a BIG difference. What goes unnoticed is the degree that it is occurring with AVXL. and why. To what benefit? By that I mean, funds generally do this to aid accumulation. But we aren't heavily owned by funds that should be close to 100% by now with all the tactics employed.

    With other bios, you don't see hit piece after hit piece EVERY SINGLE time the MACD cycle rolls over. Even now when they seemingly have little effect any longer. Like this last one talking about insider selling from FOUR years ago and a guy no longer with the company. What's next, AVXL doesn't sweep the floors but once a week and is too dirty to be a Pharma? Missling doesn't flush?

    This action is designed to hold the stock price down and that does two things. First is prevent AVXL from negotiating from a position of strength that they would have if the stock price were up. Second, it prevents early biotech take overs. Just look at poor percentage record for bios that are bought with the stock below $10. That's because CEO's of the acquiring company have to justify to their BOD and shareholders why they want to pay $30 for something they could buy all day long for $3. THAT is a hard sell and why it rarely happens.

    So when you want to blame shorts and hedge funds for past stock activity and events, I suspect BIG Pharma is the true conductor of this orchestrated action. Since well over 90% of biotech take overs occur in the first fiscal quarter of the year, I don't expect any "sustained" stock price advancement until this fall. And after AVXL gets the first bid, that the auction will truly begin. They are all flush with cash that accumulates by the day.

    Sentiment: Strong Buy

  • Reply to

    Shorts very nervous this weekend.

    by a_good_day_2 Jul 23, 2016 7:53 AM
    me2yousee me2yousee Jul 23, 2016 8:27 AM Flag

    The REAL prize is the drug. The chance for AD patients to reverse symptoms and live not only a quality life for them, but more importantly for those family members that suffer FAR more than the patient. For them, their burden returns to loving quality time until it's gone.

    More money will be made in the stock after FDA approval than before. Grossly more. No matter who buys the prize.

    Sentiment: Strong Buy

  • me2yousee me2yousee Jul 23, 2016 7:50 AM Flag

    Yep, just a few. No management requiring golden parachutes, no staff to incorporate or fire, no retirements to factor in, no buildings or equipment to unload. Pretty simple. You just move the computers and any files, throw everything else away, sweep out the place, lock the door and return the key to the building super.

    And what you get is 4 working Alheizmer drugs worth billions and a couple of cancer ones on the side.

    Sentiment: Strong Buy

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