Anyone ever involved in a break-though will tell you there is nothing subtle or nuanced about a break-through event. A scaled response according to patient history should be expected if A2-73 is what we think. Even the FDA will get it. For example, if it were me, I would be OK if I never had to solve a quadratic equation again,ever. This will be about Quality of Life (QoL).
IMO, A2-73 success will lead to a deeper evaluation of the molecule and the reason it is effective w/in one year. When that happens(and hope it is fast/obvious) numbers well past $200 are possible. This just the tip of the berg.
Let's face it, we have no idea what is really going on. None of the scenarios seem to make sense to me. Want to remain positive but it is not easy.
With luck we will see more anecdotes between now and then. Like daily updates would be fine.
Agree, lacks substance but why even bother to write such a piece? Is he helping the masses who are torn between buying Biogen or Anavex? Just all around nonsense as you say.
Political correctness(talk over) is a liberal tactic for limiting fact based rational communication. Liberals believe that misrepresenting facts (code for lying) is simply restating facts from a different point of view. Example..." It all depends on what the meaning of IS...IS". PC has allowed liberals to destroy most rational, fact based, honest discussion.
Who really knows besides Dr. M? Of course the data availability & analysis are key but this is also a build up of dramatic proportion. And why not? AVXL staff are dealing with a massive opportunity. They can demonstrate a new path for trials, a treatment for a devastating human condition, a wonder molecule. All while the rest of the world is watching. This is the trifecta of scientific achievement.. Something massive will happen at AAIC . Between now and then I expect a mix of other trials news that cannot come soon enough for me.
fat_, it is possible that June 7 will pass w/o some kind of news, that Is the pattern we have seen. But, IMO, an A2-73 trail of bread crumbs leading to AAIC in Toronto is more likely. News lately has not come directly from AVXL. The trail of anecdotes has become obvious. I am looking for a more substantial comment from an interested party(FDA, MJF, other) that will make the July conference unbearably dramatic.
Is there a pattern developing here? A2-73 seems to present the promise of great things to come for people who have been w/o hope till now. Time will tell. BTW, prayer works, just ask a cancer survivor. We all know someone who will benefit.
If this progress means these kids and their families have an effective treatment them our investment $$ and time here have been well spent.