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Geron Corporation Message Board

rokky44 126 posts  |  Last Activity: Sep 21, 2016 4:52 PM Member since: Jun 13, 2015
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  • rokky44 rokky44 Sep 21, 2016 4:52 PM Flag

    Janssen On Continuing To Advance With Telomerase Inhibitor Imetelstat

    The motion to build a partnership with Geron Corporation (NASDAQ:GERN) comes ahead of a Janssen decision on continuing to advance with telomerase inhibitor imetelstat. Janssen is nominated to come up with a decision on whether to go on with the Phase III portion of a Phase II/III trial on the coming second quarter next year. If things go forward, patient enrollment in the Phase III portion is slated for mid-2017.

    According to data, the two-armed and planned 200-patient Phase II portion of the imetelstat trial in the medication of intermediate-2 or high-risk myelofibrosis (MF) patients hasn’t been particularly promising. These patients are those who are refractory to or who have relapsed after treatment with a JAK inhibitor.

  • Janssen Pharmaceuticals, a subsidiary of the giant manufacturing company, Johnson & Johnson (NYSE:JNJ) has expanded the current partnership with the long-beleaguered Geron Corporation (NASDAQ:GERN). The newly formed partnership is for the worldwide and exclusive rights to the biotech’s oligonucleotide backbone chemistry and the novel amides for ribonucleic acid interference or RNAi. The latter is used in the prevention, treatment, and diagnosis of any disease.
    The Janssen Pharmaceuticals and Geron partnership specifically does not include any approach to bone marrow and blood originating cancers, including any product that works primarily via telomerase inhibition. These exclusions, however, have already been covered under a current deal between the two companies which was previously executed on November 2014.
    n addition to this, Janssen has also been given a non-exclusive worldwide license to monomer synthesis technology. Monomers, known to be the building blocks of oligonucleotides, are stated to be used as part of the imetelstat program. Imetelstat is a modified short oligonucleotide. The particular imetelstat program was already licensed previously in a deal made back in 2014.

    Aside from an upfront payment amounting to $5 million, Geron is eligible for development and regulatory milestones budget amounting to $75 million. This is in addition to existing low single digit royalties on the net sales of any resulting product marketed worldwide.

  • Reply to

    Is This The LittleBitches Message Board?

    by rokky44 Sep 19, 2016 4:30 PM
    rokky44 rokky44 Sep 21, 2016 1:45 AM Flag

    Make sure all you LittleBitches are posting early and often tomorrow morning..Manipulate and deceive to your black hearts desires..You know who you are you POS L-O-S-E-R-S

  • Reply to

    Just to be CRYSTAL CLEAR

    by rokky44 Sep 19, 2016 8:12 PM
    rokky44 rokky44 Sep 21, 2016 1:43 AM Flag

    And the hits just keep on coming...20 RED THUMBS DOWN for the SkunkBM.

    Too bad you're too stupid to understand what getting over 20 RED THUMBS DOWN means Skunkman...


  • slapstick funny..What about you 3 clowns..Emmerson who can't write English very well..SkunkBM who's full of fumes and BS..And of course the new Mad Poster Cheng_ho who doesn't have anything better to do with his days than to post here morning to night.

    Dumb, Dummer, and Dumbest..AND...the biggest L-O-S-E-R-S on this message board...Idiots that think alike.

  • Reply to

    Just to be CRYSTAL CLEAR

    by rokky44 Sep 19, 2016 8:12 PM
    rokky44 rokky44 Sep 20, 2016 4:05 PM Flag

    Another thing that's Crystal Clear....SkunkBM is still the most despised poster on this and the new board.

    CRYSTAL CLEAR!!!! 19 RED THUMBS DOWN on his post on this very thread.

    What a #$%$ingLoser!!!

  • rokky44 rokky44 Sep 20, 2016 4:00 PM Flag

    Fellow investors?

    You, SkunkBM, Shoeinshit, wgboxman1403, A Yahoo! User/spewage/iwaslarry are my fellow investors...I think not..If you were to say all the Geron Bashers that i'm against, then you would be right..

  • rokky44 rokky44 Sep 20, 2016 2:27 PM Flag

    You can add this line from you about why you bought back in..

    cheng_ho-"My posts are about GERN's technology and the COMPANIES VALUE.".

    So then why write on this very day.

    cheng_ho • 5 hours ago Flag

    Who would buy them? JNJ already has everything they want, what is there to sell?

  • rokky44 rokky44 Sep 20, 2016 2:23 PM Flag

    Cheng you sold out and bought back in? And this is what you're posting AFTER buying back in? It doesn't look to me like you have ANY faith in Geron..Why would you buy back in and then post negative posts? I know why...You're a lying manipulator..

    cheng_ho • 5 hours ago Flag

    Who would buy them? JNJ already has everything they want, what is there to sell?

  • rokky44 rokky44 Sep 20, 2016 12:01 PM Flag

    Whathefaulk are you still doing here cheng? Why are you still posting if you sold out of your shares?

    Are you a sickfulk or what? You've been posting since 6 am PT and you'll probably be posting all day until dark..What is your wife doing while you're posting non-stop on a message board? This is what i thought you were at the very beginning when you first started posting and here you are bashing all day long..You didn't hide it very long..

  • Spewage...i mean, iwaslarry, how do you decide which handle you're going to use for what you're about to post? You surely have some top level decisions that you have to calculate and make every single day..Which handle are you going to use to post what...That is some major life decisions you're making there Spewage..i mean A Yahoo! User...ehr...i mean iwaslarry..

    You seem to use the spewage and A Yahoo! User handles to be disruptive and post things like these that you posted this very day:

    A Yahoo! User • 1 hour 46 minutes ago Flag
    What means IMET ??
    The meaning of IMET is NOT known.

    spewage • 1 hour 10 minutes ago Flag
    0users liked this postsusers disliked this posts0Reply
    M.E. - WHAT IS IT?

    MYALGIA = Muscle pain
    ENCEPHALOMYELITIS = Inflammation of the brain & spinal cord

    THEN, you use your iwaslarry handle to post things like this next post..So i have to ask, are you dealing with demons in your head?

    iwaslarry • Sep 17, 2016 6:17 PM Flag

    About the 30 minute video ... Tefferi's attitude towards the IMbark study sponsor(s) is incredulous.

    "the only thing exciting that happened was the 20% of patients where the bone marrow architecture actually turning into normal. ... but more interestingly the mutations these patients carried all disappeared ..."

    "30% of patients have mutations in which imetelstat is not effective at all"

    personalized medicine tumor cell selectivity (u2AF1 & q157 mutations)

    "they have the preliminary interim analysis, but unfortunately, 'they' won't allow me to tell you what the preliminary results are."

  • Reply to

    Just to be CRYSTAL CLEAR

    by rokky44 Sep 19, 2016 8:12 PM
    rokky44 rokky44 Sep 20, 2016 12:39 AM Flag

    Thank you for confirming my assertion of you...IDIOT!!!

    You must have gone to the Blackmarango school for MORONS and IDIOTS.

  • Reply to

    Just to be CRYSTAL CLEAR

    by rokky44 Sep 19, 2016 8:12 PM
    rokky44 rokky44 Sep 20, 2016 12:36 AM Flag that English you just spoke? Careful or you might be mistaken for a DUMMY named Vette1967jc..or Shoeinshit..or wgboxman1403..or...well you get the point..OR..maybe not.

    You said, " crystal light rokky IS clear that he is clear that he is an skunk boy."

    Please if you're going to address me, try and be coherent and speak somewhat understandable English..Doesn't have to be proper English..I'm not that sensitive..Just understandable.

  • Reply to

    So what does this all mean?

    by shoenfield Sep 19, 2016 12:39 PM
    rokky44 rokky44 Sep 19, 2016 10:10 PM Flag

    So what does this all mean?

    Same as always...that you're still a moron of the Skunk variety.

    What will the share price be a year from regarding today's news?

    What do you care don't have any shares..Take your stupid posts and Kram them where the sun don't shine.

  • Reply to

    Just to be CRYSTAL CLEAR

    by rokky44 Sep 19, 2016 8:12 PM
    rokky44 rokky44 Sep 19, 2016 10:07 PM Flag

    You are an idiot, aren't you? The trials were to find the right dose and it looks like they found it to be the 9 instead of the 4.7...Why is that a failure? You're too stupid to be posting..

  • i listen and watch who is behind the science of Imetelstat..And what i see is the Mayo Clinic/ Dr Tefferi..I see J & J/ Janssen..I see the NEJM all involved with Geron/Imetelstat one way or another.

    What i don't care about is some message board clowns like SkunkBM, Cheng_ho, emmersonfranklin, wgboxman1403, shoeinshit all posting here to state what the share price is doing and blaming Dr Scarlett as if he's the one selling shares to drive the price down.

    First they want Dr S to "say something to defend the price"..Then when he says something (that was not negative) and the price goes down, they say something like, "Why didn't Dr S let J & J do the talking."

    These parasites are never satisfied about anything Geron..That's because they have no interest in seeing the share price rise..They are NOT long one share..But they are the most frequent posters..All day ...Everyday..Always bashing

  • Reply to

    Is This The LittleBitches Message Board?

    by rokky44 Sep 19, 2016 4:30 PM
    rokky44 rokky44 Sep 19, 2016 5:34 PM Flag

    If you sold your shares, what's your interest in posting so much? I don't need you to find information/articles on Geron..So, what are you doing wasting your time posting on a message board of a company that you hold NO SHARES in?

    You just said a 60% haircut in probably want NO PIECE of this company..I just bought some more the other day at 2.04 and am looking to BUY MORE as soon as i liquidate some of my IDCC..I have a reason to be here posting..I like the prospects of IMETELSTAT in the hands of J & J/Janssen..Yet even stating that FACT on this board, i don't post as much as a basher like you and SkunkBM..

    Again, YOU SOLD OUT of your go away and peace be with you.

  • Nobody cares what you have to say..You sold out so now go away..F-OFF

  • All i see is a bunch of loaded diaper crybabies posting here..Cheng_ho, BlackSkunkman, Shoeinshit, emmersonfranklin,wgboxman1403, and of course the spewager is back..

    It's the who's who of the biggest POS posters that have ever infested this message board with their pooping in their depends diapers..GTFOOH (getthe#$%$outofhere) all of you..Snibbling littlebitches..

  • rokky44 rokky44 Sep 14, 2016 3:03 PM Flag

    Scistats why don't you copy/paste her post here for all to read..I'm sure readers would appreciate a good read from such a respected poster as Irish.

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