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Costco Wholesale Corporation Message Board

veee4 8 posts  |  Last Activity: Jul 11, 2016 11:27 AM Member since: Feb 5, 2003
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  • Other states may follow. And the stock is up a quarter.

    http://www.seattletimes.com/seattle-news/health/court-paves-way-for-medicaid-patients-to-get-costly-hepatitis-c-treatment/

  • Jan-Jun sales of the last five years:

    2012: 208,725
    2013: 206,792
    2014: 179,144
    2015: 174,442
    2016: 149,014

    Dieselgate has merely accelerated the decline. The US market is a catastrophe for VW. Just 24,000 vehicles sold in June! For paltry sales VW is now on the hook for a 15 billion dollar settlement. Let's see: If VW made on average $3,000 per vehicle sold they'd have to sell 5 million vehicles which, at 300,000 vehicles a year would take them 16 years.

    Meanwhile VW owners elsewhere cannot expect to be compensated like US owners due to much softer consumer protection laws in their countries. They are furious being treated so differently and their anger is not with their governments or the laws of their countries but with VW who isn't treating them the same as US owners. You add to that the drop of the British Pound and potential future hurdles for the UK market and it is clear that sales in Europe will be going into the toilet as well. Diesel, which is huge in Europe, will lead the way lower.

  • Medicaid increasingly obligated to pay for Hep C treatment for all patients wasn't it. Prevailing against Merck wasn't either. The anticipated extension of HIV dominance for more than another decade with TAF went flat. Unrelenting large scale stock buy backs have not stemmed the slide toward a P/E that is flat out ridiculous.

    The only thing that Mr. Market seems to appreciate is taking the company to the next level through the acquisition of compelling external assets. No news here but it is either going to be this or a continuation of a painful trading pattern. John Milligan, your investors are waiting.

  • Reply to

    Did Merck know Durette was lying under oath?

    by veee4 Jun 7, 2016 12:27 AM
    veee4 veee4 Jun 9, 2016 1:43 AM Flag

    What irked the judge even more, she ruled, is that Durette lied about attending the conference call. In a deposition, he repeatedly denied having been on the call. He recanted from the witness stand at trial only after he was confronted with notes taken by a Pharmasset employee during the call, showing that he had participated. At that point, he pleaded a faulty memory.

    Freeman didn’t buy it. “It is overwhelmingly clear...,” she ruled, “that Dr. Durette sought at every turn to create the false impression that Merck’s conduct was aboveboard.” She blamed Merck, which she said “sponsored and encouraged” his conduct, then sought to minimize its importance by attributing the fiasco to “the failed memory of a retired employee.”

    There you go. Merck actively deceived the court.

  • Perhaps even encourage him to do so for a financial reward? I find it hard to believe that a former employee would commit perjury (a criminal offense) if there is nothing in it for him. An investigation needs to determine Merck's role in his testimony and if Durette acted alone. The real perpetrators may well turn out to be current employees and/or contracted attorneys that acted on orders of company executives. This could turn into one ugly legal morass for Merck.

  • Reply to

    Perspective on company's fault.

    by onewaytomars2 Apr 26, 2016 12:30 PM
    veee4 veee4 Apr 26, 2016 2:18 PM Flag

    "October 2012: Phenomenal results come out for mITT's 6mwt (excluding the twins). Dystrophin production, the primary endpoint, (based on known techniques at that point) were very positive. So, the dose-determination trial had a serious potential of becoming the PIVOTAL trial for AA, especially since FDASIA was just enacted. Dystrophin could be used as a surrogate marker, perhaps??"

    If you want to assign fault look no further than the originator of those phenomenal results: Dr Jerry Mendell. Almost 50% dystrophin positive fibers were reported by his laboratory. FDA was stunned to see this information published in 2013 Annals of Neurology and went to take a look. They took issue with the methods there (but didn't say there was fraud). Using mutually agreed protocols 17% dystrophin positive fibers were found in the 3 year biopsies. FDA said they were *misled* into agreeing to an AA-seeking NDA because of the inflated dystrophin numbers.

    Part 2 of the story is the overselling of the 6MWT results based on a mITT population, likewise featured prominently in the Annals of Neurology publication with first author Jerry Mendell. Sarepta didn't come up with that great idea that never took flight with the DA but was unrelentingly deployed for wooing investors. Mendell misled Sarepta on both acounts and Sarepta went on to misled investors and FDA going down the treacherous path leading us right to the edge of the cliff 4.5 years after the phase 2 study started.

  • veee4 veee4 Apr 26, 2016 12:00 PM Flag

    That is simply not true as the Prosensa and PTC trials have shown.

  • veee4 veee4 Apr 25, 2016 11:34 PM Flag

    They also focused on moving the company to the most expensive zip code to operate a biotech. Instead of doing the right things they were busy dreaming. Pure hubris. Humbled today. Unless Woodcock lifts them up I see no future for them.

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