Fri, Sep 19, 2014, 7:49 AM EDT - U.S. Markets open in 1 hr 41 mins

Recent

% | $
Quotes you view appear here for quick access.

Amarin Corporation plc Message Board

akanz2 99 posts  |  Last Activity: Sep 10, 2014 11:47 AM Member since: Feb 12, 2012
SortNewest  |  Oldest  |  Highest Rated Expand all messages
  • Reply to

    Akanz2's daily diet - - -

    by jj5rye Sep 7, 2014 10:14 PM
    akanz2 akanz2 Sep 10, 2014 11:47 AM Flag

    Youthink
    How could you verify my diet without trailing me for a week ? Ugh ... the thought of that.
    If it bothers you so much ...identify and pay for a Notary Public in the SF / Bay Area and they are welcome to inspect whats in my frig any day they choose.

    Diet is only one factor in heart disease....whether you smoke a pack a day or not , is probably a bigger risk .... unless you live at Mickey D's
    AK

  • akanz2 akanz2 Sep 10, 2014 11:38 AM Flag

    180052
    There is ample evidence that LDL levels are correlated with risk of a Cardio Vascular event . That doesn't mean that everyone with high LDL will experience an event. It is one of multiple risk factors

    You might read the Jupiter trial which showed that high hsCRP ( inflammation ) was just as important , if not more then LDL levels , in predicting risk . LDL particle numbers , Non HDL etc are other measures of risk.

    Re Lovaza . Lovaza is more effective then Vascepa in lowering triglycerides ..especially very high TG's for those at risk of pancreatitis.
    Vascepa , I believe, is more cardio protective then Lovaza because it improves the EPA/AA blood serum ratio , strengthens the caps around arterial plaque making them less likely to rupture, and does not raise LDL cholesterol .

    Since you appear new to AMRN ( 2 posts ) ...be aware that small cap biotech is risky . Do not bet more then you can afford to lose whether you are long or short .
    AK

  • akanz2 akanz2 Sep 9, 2014 11:18 PM Flag

    Just thought I would repost this as I believe it relates to the discussion taking place within DrJenkins council at the FDA
    AK

  • Reply to

    Picked Up 2,000 Shares AH @ $1.98

    by dendreonpro Sep 9, 2014 8:41 PM
    akanz2 akanz2 Sep 9, 2014 10:05 PM Flag

    Den ...$300-$400 for weekend beer money !!! ..slow down my friend , slow down ...or at least invite us over :)
    AK

  • Reply to

    Amarin ripe for the picking......

    by wilsonwagwa Sep 9, 2014 8:10 PM
    akanz2 akanz2 Sep 9, 2014 10:00 PM Flag

    Atipfrom

    You fail to mention the sub group in JELIS with low HDL / high TG ratio and the 53% reduction in events
    You also failed to analyze the section of the JELIS trial that most closely resembles Amarins Reduce It trial ...but why let these facts get in the way of your superficial analysis.

    Lowering triglycerides is but one of several things that highly purified EPA ( Vascepa ) will do ...do you know what else it does .
    Let me start you off ...Lovaza lower triglycerides also ...but ...lets see you fill in the rest .

    Regarding mineral oil as placebo . Its actually Lt purified paraffin oil and the different was explained by Dr Ballantyne in his letter to the New England Journal of Med which I assume you are familiar with.

    You are correct in that no other drug , when added to Statins has reduced Cardio Vascular events to date ...so if Amarins Vascepa does that ...the value of the company is what ???

    AK

  • Reply to

    AMRN valuation worst and best case scenario

    by staccani Sep 8, 2014 11:32 AM
    akanz2 akanz2 Sep 8, 2014 1:48 PM Flag

    Staccani
    Re Reduce It
    No drug ,when added to Statins, has been proven to further reduce CV events in a US population .
    ( there may be some exceptions to this in some sub groups using certain Fibrates )
    We are 1 -2 yrs away from knowing if Vascepa will be the first drug , that can be used with almost 0 side effects ...to reduce CV events . There is no way this trial will be stopped.

    If Amarin needs to conserve cash they will lay off all their sales staff at the end of this year and run all sales thru KOWA. They can also partner with some one to complete Reduce it

    I expect interim data analysis ( on 967 events if I recall ) sometime between Oct 2015 and April 2016 .
    They will definitely run Reduce it till then .
    JMO
    If we get an expanded label ...no problem completing RI
    They doubt they will ever turn a "nice profit " as you say on the Marine indication ...IMHO its go big or go bust
    AK

  • akanz2 akanz2 Sep 8, 2014 12:04 PM Flag

    Liver ...this is your second post on this board ...and its going down hill.

    I assume you are trying to sell dietary supplements . Your posts tell us more about the kind of person trying to sell the product...... then the product itself.

    Just look at cost to patient . Many with great insurance coverage ( especially Federal employees ) and using Amarins coupon ...get a 30 day supply of Vascepa for as low as $19 a month.

    Why would they even bother with OmegiaVia EPA or PlusEpa ?

    As I have written before ... IMHO OmegiaVia EPA provides a lower quality / lower cost alternative for those with no insurance coverage ....but with people like you trying to sell it...maybe we should all just stay away from it.
    AK

  • Reply to

    AMRN valuation worst and best case scenario

    by staccani Sep 8, 2014 11:32 AM
    akanz2 akanz2 Sep 8, 2014 11:52 AM Flag

    Staccani
    Quick thought
    1) Anchor not reinstated , label not expanded ..Reduce IT will NOT be stopped
    Company bleeds cash , partners with some one to fund completion of Reduce It.
    If Reduce it fails ...company is bankrupt. If Reduce it shows benefit ...company likely sold to big Pharma who will mount an aggressive marketing campaign
    2) Anchor SPA ..reinstated
    We all throw a huge party , congratulate each other on how smart we are ...company does well but not huge unless there is wide spread and generous insurance coverage making Vascepa affordable for all
    AK

  • Reply to

    @ Ric 74

    by akanz2 Sep 7, 2014 10:29 AM
    akanz2 akanz2 Sep 8, 2014 11:44 AM Flag

    Hi ric-74
    As regards protective order ( I'm not an attorney ) ..I would think it only applies to launch plans .
    The composition of Epanova and its methods of action is listed in their patents ..thus disclosed publicly.
    The reason I bring it up as there are 2 major binary events occurring in fairly short order with Amarin.

    First is obviously Dr Jenkins decision on the Anchor indication ..hopefully we will have a positive ( for the longs ) decision on that shortly
    The second is whether Amarin can prevent AZN from launching the sale of Epanova

    Williams posts here that AZN will have to write off Epanova because of patent infringement . I think AZN will at least try some kind of work around before doing that .
    Be interested in your thoughts
    AK

  • Reply to

    Akanz2's daily diet - - -

    by jj5rye Sep 7, 2014 10:14 PM
    akanz2 akanz2 Sep 8, 2014 12:24 AM Flag

    jj5
    Hike the Dipsea stairs with me over to Muir Woods .
    If you make it I'll buy you coffee
    If you are looking for some over weight guy livin on pizza and beer ,,,sorry mate ...you won't find him here
    AK

  • Reply to

    Akanz2's daily diet - - -

    by jj5rye Sep 7, 2014 10:14 PM
    akanz2 akanz2 Sep 7, 2014 10:43 PM Flag

    PS
    as a follow up
    I hope everyone reading this has a chance , once in their life ...to hike the Dipsea trail from Mill Valley to Muir woods CA
    Short of some of the hikes in Yosemite and New Zealand I've done ..its one of the best ...and I fortunately live right near it .
    AK

  • Reply to

    Akanz2's daily diet - - -

    by jj5rye Sep 7, 2014 10:14 PM
    akanz2 akanz2 Sep 7, 2014 10:23 PM Flag

    jj5
    I had responded to your other post but it disappeared
    Listen ...meet me any morning you like for coffee on the Plaza in Mill Valley . CA ---.others have .
    And then if you are up for it ..a hike up the Dipsea stairs over to Muir Woods ....Google it

    I'm Vegan plus Salmon ...run 3 days a week . I'm not a fast food junkie .
    My problem is an inherited lipid disorder ...about 1 in 350 American have it and all should be on Vascepa and the max dose Statins they can tolerate.
    AK

  • Reply to

    Read the core part of Sierra

    by bobobaginz Sep 7, 2014 9:26 AM
    akanz2 akanz2 Sep 7, 2014 9:34 PM Flag

    Swalchie
    Hello ...reunion time ...run up to Dr Jenkins decision
    Good to see you back on the board
    AK

  • Reply to

    New Bashers

    by cyliu1222 Sep 7, 2014 5:57 PM
    akanz2 akanz2 Sep 7, 2014 8:04 PM Flag

    Bob ...at last a post worth a thumbs up
    AK

  • akanz2 akanz2 Sep 7, 2014 8:02 PM Flag

    Melikey
    Wow ...2 posts in how many years ..where have you been ?
    Yes ..the way around the UPS problem is to try and get it shipped by US mail ...then it at least arrives in your mail box
    Now if you happen to live in the SW USA during the summer months ...and its shipped to your mail box ..and you are at work ...the condition of the Omegia Via EPA when you actually get it ???
    Yes ..there are work arounds even for that situation ...I'll let you explain what they are .

    My pt is ...the enteric coating is NOT an issue ...its delivery into your hands in the same condition Vascepa is , when you pick Vascepa up at Walgreens
    AK

  • Reply to

    New Bashers

    by cyliu1222 Sep 7, 2014 5:57 PM
    akanz2 akanz2 Sep 7, 2014 7:23 PM Flag

    Bob
    Don't you ever read the fine print " past performance is not ...etc " .
    The risk is asymmetrical ......that's all
    Risk only what you can afford to lose ...whether long or short

    By the way IMHO cyliu 1222 is one sharp poster
    AK

  • akanz2 akanz2 Sep 7, 2014 7:06 PM Flag

    Sorry ..typo ..NOT actually being sold yet
    AK

  • akanz2 akanz2 Sep 7, 2014 7:05 PM Flag

    jj5
    Interesting ....as far as I know Epanova is actually being sold yet ....due to possible infringement on Amarins patents .
    Care to update us on what's happening there
    AK

  • akanz2 akanz2 Sep 7, 2014 6:31 PM Flag

    Fantasy
    Well I see you have been with us for all of ......Sept 7th 2014 ...hmm iggy for you
    AK

  • Reply to

    New Bashers

    by cyliu1222 Sep 7, 2014 5:57 PM
    akanz2 akanz2 Sep 7, 2014 6:26 PM Flag

    CY
    Yep ...amazing how many of them have been with us since Sept 7th....What , they never heard of EPA before then ?
    AK

AMRN
1.35-0.02(-1.46%)Sep 18 4:00 PMEDT

Trending Tickers

i
Trending Tickers features significant U.S. stocks showing the most dramatic increase in user interest in Yahoo Finance in the previous hour over historic norms. The list is limited to those equities which trade at least 100,000 shares on an average day and have a market cap of more than $300 million.