what part of hernando's post was insightful and helpful?
Secondary offering tells me they are far from done moving up. Big news coming in the next few days/weeks related to new partner.
Sentiment: Strong Buy
Would it matter if it is sometime in Jan or Feb? I understand you want all the good news to come out now but frankly it does not matter when the news comes out. What will matter is who is the partner, for what indication and how much money they pay upfront and the type of deal they ink.
Personally, I think the deal is not likely to be very good because it was possibly signed (MOA) at the time when pSivida was not doing as well. Even $4 is pathetic to really be able to negotiate a good deal. $120M market cap is chickenfeed. If a Co. is paying them $50M+ they might as well buy the Co. out.
Sentiment: Strong Sell
Anyone read that garbage?
Sentiment: Strong Buy
Surge has nothing to do with ALIM move. it does have to do with an increased interest in biotechs thanks to ICPT which is tradin at ridiculous valuations, similar story for smaller biotechs like GALE.
PSDV will trade higher in the next few weeks/months in time for the secondary offering. Expect some big news from PSDV just prior to MLV dumping 20M worth of shares. I expect 3M shares to be sold in the secondary at around $6+/share.
CFO of the Co. never holding any shares show what she thinks about Isis - why is she still at Isis? Dr. Crooke any ideas?
Sentiment: Strong Sell
PSDV might sell off the 20% profit/royalty payments for a one time payment to someone I am thinking MLV. Typically the deal will have one lump sump frontend payment and future payments based on sales milestones reached over time. PSDV may make about 40M for the deal in both EU and US.
Sentiment: Strong Buy
I do not trust anything in terms of timeline projections from pSivida anymore for the simple reason the dates keep shifting in the future.
I believe they were to announce the partner for biologics late last year - but now it is mid year? I think BS. Also there are risks related to the silicon based nanotubes related to toxicity so I do not buy too much of what is being said by the Co. in terms of the potential of tethadur platform - show me the data - animal testing does not take years.
All this sounds great - what is in it for pSivida? Do you know what the financial terms were when they licensed the platform to Neurodiscovery? I do not see any milestone payments coming pSivida's way it is a huge market or perceived market.
Thanks. I am confused it looks like a subsidiary of pSivida sold world wide rights to Enigma for $2M up front and 30% royalties. Somewhere after that a news release I saw pSivida sold rights to a Chinese Co. for manufacturing rights for the device for delivery to China. Any ideas? OncoSil was acquired and they received patents for OncoSil for delivery of radio isotopes using the device to any organs. What IP does PSDV own realted to Brachsyl? Too many questions no clarity on the subject IR and Co. not making interested in clearing the air.
I hate non-earnings news releases where there is nothing new to focus on except for dilution. I expect a good deal of discussion around the secondary offering and the timing of the filing. It makes no sense for pSivida to raise cash at this stage given Alimera is doing it for pSDV. Will see, I will hate the next week.
Where is the news about partner trials? Hush and mum is the word?
Do not know what you are talking about. Shorts and longs are required to provide liquidity and support and resistance to stocks prices. Without the shorts this will never move up like a bullet, I hope the short interest rises. Problem with pSivida is the management is too passive and the secondary filing was done too prematurely. It is like a PME - management did not know how to wait for the climax and came out too early with the secondary offering.
You seem to have too many issues
a) giant ego - you seem to think just because you go google everything "pSivida" you know more about the Co. then others do. Please tell me you have some inside information in which case I will agree you know or have the ability to know more than the rest of us, until then just tone down what you think you know. About your knowledge of the technology, MOA or anything related to pharmacology, pharmacokinetics or pharmacodynamics or to that matter material science and nanotechnology please do not assume you know more than others. Even the CEO of pSivida or the chief scientific officer of the Co. does not know it all so take a hike if you think you understand how exactly all drugs will behave when delivered via tethadur or similar. In theory it is nice and it will work, but that is why clinical trials are required. Just because the Co. or its officers say so, does not mean it works. 90% of the PRs related to PIIs are exceptional in safety and efficacy, 90% of the same drugs fail in PIIIs and are not approved.
b) Let us not boast about who's #$%$ is longer in terms of who has more shares of the Co. Again you have no clue who owns what and how much here. Just because you have been here for a while and may have a lower cost basis does not imply anything.
c) Finally, what I or anyone else does with regards to trading decision related to pSDV is not your concern.
So, having said that - tone down and respect others and their opinions, just as they do yours.
Haven't I heard that before about an undervalued stock before? I just hope they are all pleasant surprises, else it will be a bummer do you agree?
I am thinking the worst case of 3 years for the product to be on the market. 2 yrs from now we should be in the face of FDA - FDA may take another 6-8 mos for approval and a Q after that for the product to be on the market.
I do see your point about Tethadur and partnerships, but given the information is sketchy and the CEO and others have discussed only one large bio-tech conducting an evaluation makes me think there is nothing else in the works.
I appreciate the slow and steady and a ultra conservative growth path, but it also translates into a slow growing Co. Please understand this is in relation to the % ownership of PSDV stock and we are discussing institutional interest in the Co.
In this crazy market thanks to easy money, money is chasing money and fast growing Cos. Popular and prudent belief is to limit dilution and not borrow too much money which may make sense in a tight monetary policy market. Currently when money is cheap, pSDV should raise the 19.5M or whatever ATM they have filed even if it implies they have to sell about 6-7M shares. Increase the burn rate from the current 2-3M/Q to about 10M/Qtr for the next 2-3 Qtrs but have several trials going to evaluate safety and efficacy of Tethadur platform and applications for several different indications.
Capital markets will value pSDV 10x-100x the current valuation if they have 4-5 PIIs going in areas like Oncology, immune system (auto immune - RA. lupus etc) and metabolic disorders (thyroid, diabetes etc). There is nothing to prevent pSDV to eventually get there and possibly have treatment options for several indications, but based on the current spend and interest in the platform the growth rate will likely remain slow for the next 4-5 years, I mean an explosive growth.
Designing a good product or even a great product is 1/2 the battle. Timing to market is more important, if you know the story of MSFT, APPL and Xerox you will understand the difference, I hope. It is not about how great the product is, who gets there first. Remember the risk for a microcap like pSivida is IP risk, larger Corporations with deeper pockets can infringe on their patents and mire a small Co. in IP litigation for years, challenge and re-challenge every aspect of the patent and eventually you will have a product in market which infringes, IP is weakened by the repeated challenges and changes to claims and the smaller Co. has little money and survival is a battle. Seen that too often so recognize speed to market is more important than being prudent and safe. Do not assume others are not working on similar technologies including Si so we are not the only game in town, IP risk is equally high given the $$$s involved.
Dr. Ashton may be doing a disservice to the shareholders by being ultraconservative for too long.
Make your bullish case now, but do not disregard the IP challenge issue without researching it.
You seem to be too sure about pSi only game in town for injected, timed released silica. Maybe you are right to a certain extent for Ophthalmology but a lot of us are here for beyond Ophthalmology. I am not saying Optho is not lucrative, but the true value of Tethadur is in the Onco, Inflammation & Infectious, Autoimmune and Metabolic areas. It does get competitive, you should research si and non-si based porous sustained delivery systems, nano structures delivery systems etc. Read some research papers there are over 200 on the subject and you will see it is highly competitive area, we are not the only game.
When it comes to biologics and patent extension for blockbuster Oncology products, look at alternatives like Halozyme's technology as well. There are various ways to extend the life of a drug, Tethadur is one mechanism.
My only concern is everyone is reading too much into the PR machine right now and I am not seeing anything from the Co. In the meantime there are some die hard bulls here who seem to think they know it all and think they have discovered something in pSi which is a game changer in the pharma world. I remain optimistic but I am a pragmatist. I want to see the Co, succeed just as the next guy here but I have been fooled way too many times in this business and I need to see some partners lay some serious cash on the table for Tethadur and fast. Long before I start to count the chicks in the meantime, while there are others on the board who seem to be jumping on every statement issued by the Co. or its PR machine and are ready with cork screws in their hands waiting to pop open the bubblies....I just have to tell them baba - stop dreaming.
Show me the MONEY- Show me the MONEY, show me the money, show me the money.
They will run the clock, if you have not got used to the idea you should learn to connect the dots.
FDA has successfully delayed Alim and pSi for years.
FDA Chairwoman is married to a hedge fund CEO making 120M/year in sal and comp.
One of the Top 10 investments of the hedge fund is in Regeneron
You really think the CRLs had nothing to do with a need to delay the drug as much as possible?
Go research everything and wonder why an important post in the Govt. agency which is one of the most lucrative and influential posts in the highly speculative business was not asked to divest investments prior to confirmation and/or why someone with very high conflict of interest was allowed to be confirmed for that post?
I tried posting earlier with the urls for every one of these facts but Yahoo has its ideas on urls. Do your on DD and figure out why there is some merit to my line of thinking. I am tired of these Govt agencies manipulating and large financial houses stealing money from small investors like us.
Whatever I expect FDA to run the freaking clock on ALIM. ALIM and PSDV also know this but no one will confirm it for you.
If there is nothing wrong why would the a public official in a key position not required to divest their investments?
Why are there boutique research firms which often doing illegal activities for large cap financial power houses? And no one is ever prosecuted?
Big money and large stakes compel large firms to do everything possible to safeguard their investments. Google Seattle Times "Selling Drug secrets".
I am not saying there was definitely something illegal done, but there is a possibility and I have doubts, because there is a possibility of conflict of interest. If I was the official in question, I would have divested just to rule out any doubts and possibilities - if you do not you subject yourself to all types of speculations.
I worked for the financial industry and I was forced to move my portfolio to fidelity, I had to get an OK to buy stock and was subject to holding requirements. I was not allowed to short sell and I was not allowed to speculate by way of options. Read CFA ethics requirements and then wonder why the right hand man of Buffet who was likely to replace Buffet (when he retired) was involved in an insider trading case but never prosecuted? It was Berkshire Hathway's shareholders money which was possibly lost - why was there never any action taken in that case? His resigning from the post is sufficient? Martha S. went to jail and gave up control of her Co. for life over 150K in gains/protected losses, the Berkshire guy gained 3M. It is not about the magnitude but even if I were to look at magnitude it does not make sense. Unless there was a lot to lose by prosecuting him the risk of him spilling the beans on everyone was possibly compelling.
Lower ranked foot employees are required to abide by the ethics laws but the large fish in the financial sector are spared? Even within the community there isn't a level playing field.
It is all a figment of my imagination - enjoy the rest of the day.
Looks like Alimera threw in the towel and contracted a sales force to market the drug for them. License the drug from someone and contract someone else to market the drug - way to go. Small pie getting smaller is my reaction. Short term it may sound good because there may be a ramp up in sales but longer term how much is Alimera giving away is to be seen. Quintiles could possibly be getting 30% for their efforts. Essentially the $5500-$8500 number just shrunk to about $4000 avg. selling price. Quick get the calculators and start multiplying with the patient population derive the revenue and figure out the share price........
Put some more lipstick on the pig. Alimera just proved they do not know how to market the drug, do not have the resources and it was not a successful launch, still not bad to admit your failure and give the mandate to someone else - I just hope it does not languish on the back burner of Quintiles Sales Reps and it is not going to be a tier 4 product to detail - "oh Doc, how are we doing on time? If you still have time I would like to discuss this phenomenal product Iluvien...., if not we can discuss next time we meet which is say 60 days from now?" Unless they actually target the Doc specifically for Illuvien there is no way you get a big bang for the buck marketing the drug. If anyone here understands how SFA systems work and how docs are "quintiled" you will see the # of docs to call and whom to call is based on a specific drug, the rest of the drugs detailed in that visit are evenly distributed - not necessarily targeted. You may call a Doc who is not sold on the idea of Illuvien and will never prescribe it or you might over call on a 1st Quintile Doc who does nothing but recommend Illuvien- the middle of the bell curve is missed because you did not target Docs specifically for Illuvien. Anyone think otherwise must think, Quintiles is not going to dedicate 100 or more reps specifically for Illuvien marketing.