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BioLineRx, Ltd. (BLRX) Message Board

asswipesforbush 15 posts  |  Last Activity: 16 hours ago Member since: Oct 13, 2009
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  • asswipesforbush by asswipesforbush 16 hours ago Flag

    Per your request so you can start explaining but in the end you could just admit you are wrong and reevaluate based on the correct info.

    A number of patients on study received additional treatments with other agents following discontinuation of study treatment ONE --in accordance with the clinical practices of individual enrolling centres. IN ACCORDANCE WITH CLINICAL PRACTICE AND KNOWN OR SHOULD HAVE BEEN KNOW TO ONCY FROM DAY1) Thirty of the 118 patients in the loco-regional group received at least one therapy with other agents after study therapy was discontinued. TWO A greater number of patients in the control arm received post-discontinuation therapy versus the test arm. (MORE CENSORING IN CONTROL ARM)This imbalance created a "confounding," or distorting, effect on OS (CENSORED FOR SEEKING ALTERNATIVE THERAPY NOT "FEVER":) (Pazdur; The Oncologist 2008, 13:19-21), as THREE- such additional therapy can extend the patients' lifespan beyond that expected from receiving the study therapy. EXTENDED LIFESPAN FOR THOSE WHO SOUGHT SUBSEQUENT THERAPY. Eighty-eight loco-regional patients did not receive additional therapy and an analysis of these patients showed a median OS of 150 days (21.4 weeks) in the test arm FOUR (n=50) versus 115 days (16.4 weeks) in the control arm (n=38). 18 CENSORED IN CONTROL COHORT WITH SMALLER STARTING N--12 CENSORED IN TEST WITH LARGER STARTING N

    One last little point regarding the appropriateness of censoring available data. You can read the press release yourself but the company said that they refuse to show you the data because of an imbalance in those seeking treatment. How big was that imbalance that caused this horrid confounding ? The answer my friend is 6. 18 in control and 12 in trial. If we assume (as we should) that the 12 in the trial arm cancel out 12 in the test arm. the total "confound" is a function of only 6 patients. The data as presented is pure garbage.

  • Price the day before the release of the first "good news" 2.52 --price the next day 1.92-- a loss of only 20%. Grim Boy What could dthe have missed?? Price on the day before the release of the second "good news" 1.92 price today 1.59 a loss of only 20% Grim Boy what could they have missed? in total a loss of about 37 % in less than 6 months. In light of the foregoing the rational thinker might reexamine his thesis. But I guess the market is incapable of understanding all y'all's brilliance. 100k now worth about 60k. 40k lost and never coming back. But keep whistling past the graveyard.

  • asswipesforbush by asswipesforbush Mar 22, 2014 9:49 AM Flag

    Is supposed to take place at 88 events. That moment should be arriving any day now. That will be a bit odd trying to do 2 interim analyses at the same time. Delay is not our friend.

  • asswipesforbush by asswipesforbush Mar 11, 2014 10:17 AM Flag

    Yoink!

  • Reply to

    Obama's to-do list for the week....

    by captncarl Mar 1, 2014 11:13 PM
    asswipesforbush asswipesforbush Mar 2, 2014 7:37 AM Flag

    We'll look what cat borked up. Another teabag. Bit of a chicken hawk too. I guess that goes with the territory have good day hating life

  • asswipesforbush by asswipesforbush Feb 20, 2014 8:39 PM Flag

    "He has just got to be looking at survivors with effectively a Complete Response"

    Honest to god, i want to know who your writer's are!!! Please stop my sides are aching. Have you consumed a lot of Newcastle ale. They say it makes you go crazy old chap. Are you Benny Hill?

  • Reply to

    What do my donks think

    by rationalthought11 Feb 19, 2014 12:06 PM
    asswipesforbush asswipesforbush Feb 20, 2014 6:45 AM Flag

    Just when you thought it impossible to find folks schtoopider than the Kenny's, scouts and grim boys of the world you get a post like this. Of course they are still recruiting.

  • asswipesforbush by asswipesforbush Feb 7, 2014 1:45 PM Flag

    It's official. Jeremy Grushcow resigned in October without any announcement by ONCY. Apparently longer isn't better when it come to General Counsels. & months and GONEEEEEEEE

  • Reply to

    Modeling this out

    by anotherday1225 Feb 4, 2014 7:45 PM
    asswipesforbush asswipesforbush Feb 6, 2014 1:07 AM Flag

    Ok so what? How do you get to your guess that there are twice as many control patients in the 66 events. What are your survival assumptions

  • Reply to

    great job ignoring the RAT people

    by minktrader2014 Feb 4, 2014 7:19 PM
    asswipesforbush asswipesforbush Feb 5, 2014 11:47 AM Flag

    Scout you are a laugh riot. High degree of intelligence? Now that is rich. Who writes your material?

  • Reply to

    Rented The Butler from Redbox last night

    by drjohncar Jan 29, 2014 7:46 AM
    asswipesforbush asswipesforbush Jan 31, 2014 6:28 AM Flag

    I see that Moderate jack is still fuming that a Harvard educated black man rose to be prez while his own miserable existence will go unnoticed by all of humanity. Are you sure you didn't pause the butler a few times in order to take a few peeks at Fox News?

  • Reply to

    Elitist President

    by speedydekker Jan 30, 2014 6:56 PM
    asswipesforbush asswipesforbush Jan 31, 2014 6:21 AM Flag

    Been away a while but I see the schtooopid brigade is still chanting the racist slogans of their masters at fox. There is no cure for schtoopid

  • asswipesforbush by asswipesforbush Jan 27, 2014 7:43 PM Flag

    PfS data promised in 2013. But never delivered. Another miss by the gang with forked tongues. But I guess longer is better

  • In ONCY land.

    Right now, based on the KM curve from the Zenda pt refractory head and neck paper with docetaxel treatment, there should only be one control patient around. This paper is not even necessarily true second line. If you look at the true second line papers, noone from the control should be around.

    So they must be unblinding at 10%. By my calculation there should only be about twelve treatment pts around (from the PII KM curve). There could be slightly more than 16 (keeping the total above 10% at this point). It is easy to imagine that since they are treating true second line (not 38% 3rd through 5th line like the European PII) and they are continuing treatment with REO beyond chemo.

    OS prediction: control; 120 days plus minus 30 days, treatment; 295 days plus/minus 40.

    GOOD WORK!!! you got half of it right and only missed by about 100% on the other half.

  • Reply to

    Girls girls girls

    by rationalthought11 Jan 21, 2014 2:21 PM
    asswipesforbush asswipesforbush Jan 22, 2014 9:24 AM Flag

    But mommy I miss nome's hilarious predictions and the moronic mewling of Kenny grimboy and speed mutt I even miss the filthy psychopath. Bailey why did you do this to me? Ronree IM so ronreee

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