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SIGA Technologies Inc. Message Board

beavertail_splash 1431 posts  |  Last Activity: 3 hours ago Member since: Apr 13, 2007
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  • beavertail_splash beavertail_splash 3 hours ago Flag

    maybe wedgie could send it my way to help offset the losses I've incurred investing here. I have no pride.

  • Reply to

    As a shareholder

    by beavertail_splash 8 hours ago
    beavertail_splash beavertail_splash 4 hours ago Flag

    I missed #7 a), b), c)
    thanx circone as was only in GERN during the last two years. The SP hit a high of $4.99 even after dilution almost 2 years ago on February 18/14. I re-established my position shortly afterwards think the worst was over. Boy did I get taken.

  • Reply to

    As a shareholder

    by beavertail_splash 8 hours ago
    beavertail_splash beavertail_splash 8 hours ago Flag

    "Fiduciary obligations exist to ensure that those who manage other people’s money act responsibly in the interests of investors, rather than serving their own interests. The nature of the fiduciary relationship means that a fiduciary is expected to be loyal to the person to whom he or she owes the duty. In particular, fiduciaries should not put their personal interests before the duty, should avoid conflicts to the extent possible (and, if they cannot be avoided, conflicts should be minimized, disclosed and carefully managed to prevent any breaches of loyalty obligations), should ensure that their fiduciary duty does not conflict with other legal duties or their own interests, and should not profit unreasonably from their fiduciary position.
    Fiduciary duties are generally seen as requiring a higher standard of performance than those that are generally imposed in contracts."
    ....has this CEO met with his fiduciary responsibility? Don't tell me or splash your vote all over this board just vote on the next proxy.

  • beavertail_splash by beavertail_splash 8 hours ago Flag

    to rocky squirrel, from one rodent to another had you followed "Sdrawkcabeman, Irishtrader52, Earfool, Biopearl, Tazmatic and a few others that have what it takes to write an informed or at least, interesting to read post." and based your investment DD on that, buying into GERN's chipmunk's pension plan would have ruined your financial portfolio as it has mine. Nothing Chippy has delivered, even the Jansson deal (which barely got a SP boost) has moved this SP up to where it should be based on Imet's development and market potential. The Mayo under T-fairy was great in developing the drug in it's early stages, Janssen's 2 new world trials for establishing IMET's viability and eventual expedited approval could never have been done in house by GERN. This being said, although the Chipper did get the deal down, which I give him credit for and should be adequately compensated for when the time comes, he has deliberately sandbagged ever since and has caused undue selling pressure by ;
    #1. his publicly stated acquisition intentions all through 2015 and the Fidelity shelf registration last Sept. which really killed the SP.
    #2. his delayed booking the $35mil by a year
    #3. he has yet to promote the drug within safe harbor guidelines for market valuation potentials supporting investment DD
    #4. he has not yet PR'd EU ODD designation for IMET ( a reportable event)
    #5. he needs to clarify the milestone payment requirement payments for the new Janssen trials rather than this board trying to decipher the terms of that rather lengthy collaborative contract with them. The market hates uncertainty and this guessing has added to it.
    #6. he needs to stop going from racing car management analogies to sticking to the knitting as referencing what he is doing with the large sum of money I have entrusted him with and stopped feeding my shares to the sharks.

  • Reply to

    Changes to NCT02426086 on 2016_01_27

    by anne_hi Feb 3, 2016 12:52 AM
    beavertail_splash beavertail_splash 13 hours ago Flag

    Abstract
    Koziel JE, Herbert BS.
    Breast Cancer Res Treat. 2015 Feb;149(3):607-18. doi: 10.1007/s10549-015-3270-1. Epub 2015 Jan 28
    "Cancer stem cells (CSCs) are thought to be responsible for tumor progression, metastasis, and recurrence. HER2 overexpression is associated with increased CSCs, which may explain the aggressive phenotype and increased likelihood of recurrence for HER2(+) breast cancers. Telomerase is reactivated in tumor cells, including CSCs, but has limited activity in normal tissues, providing potential for telomerase inhibition in anti-cancer therapy. The purpose of this study was to investigate the effects of a telomerase antagonistic oligonucleotide, imetelstat (GRN163L), on CSC and non-CSC populations of HER2(+) breast cancer cell lines. The effects of imetelstat on CSC populations of HER2(+) breast cancer cells were measured by ALDH activity and CD44/24 expression by flow cytometry as well as mammosphere assays for functionality. Combination studies in vitro and in vivo were utilized to test for synergism between imetelstat and trastuzumab. Imetelstat inhibited telomerase activity in both subpopulations. Moreover, imetelstat alone and in combination with trastuzumab reduced the CSC fraction and inhibited CSC functional ability, as shown by decreased mammosphere counts and invasive potential. Tumor growth rate was slower in combination-treated mice compared to either drug alone. Additionally, there was a trend toward decreased CSC marker expression in imetelstat-treated xenograft cells compared to vehicle control. Furthermore, the observed decrease in CSC marker expression occurred prior to and after telomere shortening, suggesting that imetelstat acts on the CSC subpopulation in telomere length-dependent and -independent mechanisms. Our study suggests addition of imetelstat to trastuzumab may enhance the effects of HER2 inhibition therapy, especially in the CSC population."
    Hmmmmm interesting BC combo therapy potential.

  • beavertail_splash beavertail_splash 14 hours ago Flag

    still below the 55% number it was in 2014

  • beavertail_splash beavertail_splash 14 hours ago Flag

    so it only covered the time when SP was in the $5's. Come January we could have had a huge sell off and that wont be reported till the end of March. Therefore Institute ownership is meaningless speculation at this point. Kinda like technicals, which I put more credence in SP ST movement

  • Reply to

    Changes to NCT02426086 on 2016_01_27

    by anne_hi Feb 3, 2016 12:52 AM
    beavertail_splash beavertail_splash 14 hours ago Flag

    anne you're the one dropping bunk on the board with implying Switzerland will help usher in EU approval when it's not even part of the EU regulatory board. That's a fact and your a deceiver pretending to have some inside insight sway.

  • Reply to

    Changes to NCT02426086 on 2016_01_27

    by anne_hi Feb 3, 2016 12:52 AM
    beavertail_splash beavertail_splash 14 hours ago Flag

    trust me on this anne Canada will not approve anything the FDA doesn't first approve. Their northern Canadian woodland Canadian Health Office, although very pretty, is merely an ice fishing hut equipped with rubber stamps for any notice sent up to them by the FDA.

  • Reply to

    I am a shareholder

    by rokky44 Feb 4, 2016 1:32 AM
    beavertail_splash beavertail_splash 14 hours ago Flag

    "Fiduciary obligations exist to ensure that those who manage other people’s money act responsibly in the interests of investors, rather than serving their own interests. The nature of the fiduciary relationship means that a fiduciary is expected to be loyal to the person to whom he or she owes the duty. In particular, fiduciaries should not put their personal interests before the duty, should avoid conflicts to the extent possible (and, if they cannot be avoided, conflicts should be minimized, disclosed and carefully managed to prevent any breaches of loyalty obligations), should ensure that their fiduciary duty does not conflict with other legal duties or their own interests, and should not profit unreasonably from their fiduciary position.
    Fiduciary duties are generally seen as requiring a higher standard of performance than those that are generally imposed in contracts."
    ....has this CEO met with his fiduciary responsibility? Don't tell me just vote on the next proxy.

  • Reply to

    I am a shareholder

    by rokky44 Feb 4, 2016 1:32 AM
    beavertail_splash beavertail_splash 15 hours ago Flag

    rocky squirrel, from one rodent to another had you followed "Sdrawkcabeman, Irishtrader52, Earfool, Biopearl, Tazmatic and a few others that have what it takes to write an informed or at least, interesting to read post." and based your investment DD on that, buying into GERN's chipmunk's pension plan would have ruined your financial portfolio as it has mine. Nothing Chippy has delivered, even the Jansson deal (which barely got a SP boost) has moved this SP up to where it should be based on Imet's development and market potential. The Mayo under T-fairy was great in developing the drug in it's early stages, Janssen's 2 new world trials for establishing IMET's viability and eventual expedited approval could never have been done in house by GERN. This being said, although the Chipper did get the deal down, which I give him credit for and should be adequately compensated for when the time comes, he has deliberately sandbagged ever since and has caused undue selling pressure by ;
    #1. his publicly stated acquisition intentions all through 2015 and the Fidelity shelf registration last Sept. which really killed the SP.
    #2. his delayed booking the $35mil by a year
    #3. he has yet to promote the drug within safe harbor guidelines for market valuation potentials supporting investment DD
    #4. he has not yet PR'd EU ODD designation for IMET ( a reportable event)
    #5. he needs to clarify the milestone payment requirement payments for the new Janssen trials rather than this board trying to decipher the terms of that rather lengthy collaborative contract with them. The market hates uncertainty and this guessing has added to it.
    #6. he needs to stop going from racing car management analogies to sticking to the knitting as referencing what he is doing with the large sum of money I have entrusted him with and stopped feeding my shares to the sharks.

  • Reply to

    I am a shareholder

    by rokky44 Feb 4, 2016 1:32 AM
    beavertail_splash beavertail_splash 15 hours ago Flag

    I could care less after all it's your money he's taken as well.

  • beavertail_splash beavertail_splash 17 hours ago Flag

    that was really bright!

  • beavertail_splash beavertail_splash 17 hours ago Flag

    The last great depression lasted for a decade. US collectively had relatively speaking little debt back then and the run on the US$ was triggered by the Feds pursuing a tightening monetary supply in light of weakening economic demands. Run on the banks and run on the dollar fleeing into gold triggered the meltdown when the investing public panicked and lost faith in the greenback(which was backed by bullion back then)
    A Depression on the scale of that in 1929 couldn't happen exactly the way it did before. Central banks around the world, including the U.S. Federal Reserve, are sooooo much more aware of the importance of monetary policy in regulating the economy albeit limited as it may. There is only so much monetary policy can do to offset fiscal policy. The incredible size of the U.S. current account deficit, and the national debt, could possibly trigger an economic panic far worse than the one in 1929 that would be difficult for even monetary policy to affect. No one really knows, since the current U.S. debt level is unprecedented. $20 trillion current and $225 trillion unfunded liabilities backed by the all-mighty unbacked US dollar.
    The current thinking is that a Great Depression could not happen again because the global economy is much more integrated, and all central banks are working together to make sure it doesn’t.
    happen. Just watch when they start breaking rank. The big demand for bullion has been by central banks so far....wonder why?

  • beavertail_splash beavertail_splash 22 hours ago Flag

    Hmmmmmm so that was a recent update? Likely from Dec where in FACT SP was holding in the $5's. We've had a tremendous sell off since(45%) and those tute sells won't show up for another 3 months. Wouldn't get overjoyed just yet. price is still falling.

  • Reply to

    GERN Valuation

    by blackmarango Feb 4, 2016 2:38 PM
    beavertail_splash beavertail_splash Feb 5, 2016 12:10 PM Flag

    AGIO just experienced a 10% drop in SP within 3 hrs trading today. I takes GERN at least an entire 8 hrs to do the same. I'm sticking with slow and steady wins the race down.

  • beavertail_splash beavertail_splash Feb 5, 2016 12:02 PM Flag

    GERN is nearing at 50% loss. Maybe Maine's a good contrarian indicator. He was hell bent on selling AST shares the minute they were issued last year missing the short squeeze that took it to $15 and down again. Never saw that coming. I must confess I sold out in the 5's thinking it couldn't go any higher and averaged down on more GERN 8=3(

  • beavertail_splash beavertail_splash Feb 5, 2016 10:05 AM Flag

    all hail Caesar! I
    I mean Chippy

  • Reply to

    BULLISH-BUY-ADD-HOLD GERON ....

    by tradingadollar Feb 5, 2016 9:14 AM
    beavertail_splash beavertail_splash Feb 5, 2016 9:19 AM Flag

    joanie has been lying like a rug for 2 years about a short squeeze we have yet to see.
    Charts posted a 3 black crow indicator last week...they better be lying or we're in for some more serious HURTING

  • beavertail_splash beavertail_splash Feb 5, 2016 9:11 AM Flag

    or being a GERN shareholder guilty
    hachahachahacha,cha

SIGA
2.460.0000(0.00%)Mar 13 4:00 PMEDT