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Isis Pharmaceuticals, Inc. Message Board

biotechbuzz 21 posts  |  Last Activity: Mar 11, 2013 1:22 PM Member since: Mar 7, 2011
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  • Reply to

    Vical Shareholder meeting

    by biotechbuzz Mar 7, 2013 7:00 PM
    biotechbuzz biotechbuzz Mar 11, 2013 1:22 PM Flag

    I will repeat question Dipsea, how do you know this?

  • Reply to

    Vical Shareholder meeting

    by biotechbuzz Mar 7, 2013 7:00 PM
    biotechbuzz biotechbuzz Mar 8, 2013 2:15 PM Flag

    Dipsea, how do you know this ? It has not been posted on Vical website or web.

  • biotechbuzz by biotechbuzz Mar 7, 2013 7:00 PM Flag

    Anyone know where and when this year ?

  • biotechbuzz by biotechbuzz Nov 14, 2012 11:13 AM Flag

    He has been saving newbies from Isis for years. In the interim though he has got droves into Vical in the 4's.His recent rant that Vical was locked and loaded (whatever this means) and then it has tanked. Is his head buried in the sand from embarrassment ? Come out and play Dark.

  • Reply to

    Reecent Price Escalation

    by biotechbuzz Oct 3, 2012 10:58 AM
    biotechbuzz biotechbuzz Oct 3, 2012 11:59 PM Flag

    He is listed as a director at the " Great Bay Foundation " located in Maine I believe. The addresses match Sec filings so it is the same. Interestingly the head of the foundation is mr. Peter green leaf who is head of medlimune, owned by Astra Zeneca. They are very involved in vaccine research.
    Now somebody else work on the puzzle. I still believe that the Transmeta history is very interesting. Transmeta was a leap ahead in innovation years ago. Singer showed up as an early investor. Now somebody has to know his occupation at least.

  • Reply to

    Reecent Price Escalation

    by biotechbuzz Oct 3, 2012 10:58 AM
    biotechbuzz biotechbuzz Oct 3, 2012 12:37 PM Flag

    Thanks for your reply. I really have not heard of these 3 or 4 private unfiled SEC documents. How does happen and why are they exempt from filing in a public company?

    We have been through James. R. Singer's history in Vical many many times. But no new info comes to surface. It is amazing. You can more information about patents and intellectual property than you can about this man.

  • biotechbuzz by biotechbuzz Oct 3, 2012 10:58 AM Flag

    Can some kind person explain the recent volume spike and share/price increases while no substantial news or events ? No new SEC filings. No insider trading. And now back to relatively normal volume and stability. Anyone......Anyone.....Anyone.....
    Mr. Singer is still the mystery man of the decade. To this date this board has neither identified the who, occupation, or other pertinent facts about an elusive investor that places a massive position in Vical. How does this happen with such stealth? He went from TRANSMETA to biotech (see SEC filings) Transmeta was one of the high tech stories of the decade. He somehow shows up as in early shareholder before buyout. This is not some day trader that inherited grandma's money. He has to be someone who has an incredible depth of knowledge of science and technology. This is evident by many events. For example: How does an investor with this much cash remain so invisible from Mr. Google , Yahoo, and other search machines ? It takes knowledge and process. Yes.......I believe that Mr. James R. Singer believes that either Vical will be bought out at substantial premium or that the eminent trials and pipeline are alive with opportunity.

    This " ain't " no ordinary biotech folks. Something is smoldering.

  • Reply to

    Complementary Therapies

    by pat_robbersin Jan 29, 2011 5:33 AM
    biotechbuzz biotechbuzz Sep 25, 2012 11:42 AM Flag

    Good call with BMY way back in Jan 2011 Blueberries................

  • Reply to

    riding the tail of VIVUS

    by aosjdhdjduryffjfjfj Mar 26, 2012 9:00 PM
    biotechbuzz biotechbuzz Mar 26, 2012 9:27 PM Flag

    Perhaps this may happen. But the probability of a favorable response is good. Why? The European approval. There seems to be considerable support that the U.S. will follow suit. The momentum is not stopping but just beginning. It;s all a crap shoot. You can be in the field. Or you can take the odds behind the line where the smart money is always.

  • Reply to

    Who is James R Singer?

    by tomcheeks Jan 20, 2012 11:15 PM
    biotechbuzz biotechbuzz Jan 22, 2012 6:07 PM Flag

    I have seen many errors with the address and name initials. In the sec filings there are many different addresses used. People are entitled to privacy and I think it is important to respect the privacy of others. However, in a company which is traded publicly is available to be scrutinized by the public and the investors it attracts.

    My money and investments are important to me. I want to know about material events, information, and other variables surrounding the investment.

    When a man buys 40 million worth of stock and becomes the largest shareholder I want to know a little bit about the person or entity.

    Conversely, I want to make sure that the company is following the basis requirement of informing shareholders of material facts, maximizing shareholder wealth, and making sound decisions.

    I would still like to know what Singers occupation is. Lawyer, doctor, banker, or just a rich kid who did nothing for it except being born into it. Don'tcare much for rich kids.

  • Reply to

    Who is James R Singer?

    by tomcheeks Jan 20, 2012 11:15 PM
    biotechbuzz biotechbuzz Jan 21, 2012 12:57 AM Flag

    Nice try. Not the same man though. The addresses of his sec filing and the Great Bay Foundation match up. Unfortunately, there is little available about this man. The law firm listed in the foundation records is listed as Vacovec, mayotte, and Singer. But this firm has no James Robert Singer. Only a Paula Singer.

    Thats all folks.

  • Reply to

    Questions about Mr. Singers purchase...

    by ballman6711 Jan 11, 2012 12:34 AM
    biotechbuzz biotechbuzz Jan 20, 2012 9:57 PM Flag

    Do not know his occupation but he is part of the Great Bay Foundation in Maine. He is listed as a director and donor.

  • Reply to

    SNTA share accumulation way up:

    by techtrader97 Jan 19, 2012 8:00 AM
    biotechbuzz biotechbuzz Jan 20, 2012 3:55 PM Flag

    agreed

  • biotechbuzz by biotechbuzz Mar 22, 2011 10:05 AM Flag

    President of Nestle on CNBC this morning stressing how important biofuel is.

  • Reply to

    Speaking of dancing ! ZACK

    by darkouttonight Mar 14, 2011 10:12 AM
    biotechbuzz biotechbuzz Mar 14, 2011 2:20 PM Flag

    So sad you have to hide behind innuendo and through zack. Speaking in the third party is like speaking from a script. You just can't get the truth out there without first hand knowledge.

    There is no large following dark. Just a few curious hecklers, newbies, and a band of small investors. Your innuendo is not moving large block trades. You are amusing though.

    As for Andrew, please say hello.

  • Reply to

    Speaking of dancing ! ZACK

    by darkouttonight Mar 14, 2011 10:12 AM
    biotechbuzz biotechbuzz Mar 14, 2011 12:03 PM Flag

    So sad that zack has to spend his whole life speaking in innuendo. It must be so frustrating, especially since zack's handler tried so hard to be the whistle blower and warn the siren. Tell me, did the same thing happen at the other factories? Poor zack just keeps going in and out of these factories.

  • Reply to

    Vical the next MSFT

    by beachbarbob Mar 3, 2011 1:32 PM
    biotechbuzz biotechbuzz Mar 11, 2011 3:42 PM Flag

    I believe that the message was specific enough for this individual to become refreshed with this document. If not, and certain information continues, then let the dance begin.

    Hey, anybody seen.................

  • Reply to

    Vical the next MSFT

    by beachbarbob Mar 3, 2011 1:32 PM
    biotechbuzz biotechbuzz Mar 11, 2011 1:52 PM Flag

    I might remind the public that if you enter an agreement that restricts one from using disparaging remarks then one should honor that committment or else possibly encounter consequences.

    Just a friendly reminder to the public.

  • Reply to

    replace tobacco crops

    by biotechbuzz Mar 7, 2011 5:57 PM
    biotechbuzz biotechbuzz Mar 8, 2011 3:40 PM Flag

    Let me qualify this before a mass of replies. Temperature to be consistently ABOVE 50 degrees farenheit.

  • Reply to

    replace tobacco crops

    by biotechbuzz Mar 7, 2011 5:57 PM
    biotechbuzz biotechbuzz Mar 8, 2011 3:36 PM Flag

    The temperature for optimal growing conditions is to "consistently have a 50 degree F climate".
    This is as per Viaspace and many perodicals in the biomass industry. However, the replacement of a cancerous crop like tobacco with Giant King Grass achieves other objectives than just optimizing growth.. Perhaps one could restate the equation and ask how to optimize the engergy and social objectives. Further, why not subsidize small farmers to grow Giant King Grass instead of tobacco. This grass will grow almost anywhere. Optimization could be achieved over time in colder climates. Sequence the gene, isolate the part of the gene which is sensitive to cold, and change the conditions in which it can thrive in.

    It could be done. As a shareholder I would encourage the dialog. As a consumer I would encourage the self reliance the USA could achieve from moving off oil consumption.

    It can be done and will be done. The question is who will be the most aggressive to capitalize on the opportunity. Who am I ? Just a concerned man and shareholder.

ISIS
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