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biotuesday 14 posts  |  Last Activity: Oct 21, 2014 9:34 AM Member since: Oct 25, 2011
  • Today's BioTuesdays feature article.

  • Amarantus Bioscience Holdings’ (OTCQB:AMBS) master services agreement with the lab services arm of ICON (NASDAQ:ICLR) puts Amarantus on the road to commercializing its LymPro diagnostic blood test for the early detection of Alzheimer’s disease (AD)…..

    See BT for rest of today's feature article on AMBS

  • Leerink Partners has upgraded Amicus Therapeutics (NASDAQ:FOLD) to “outperform” from “market perform” and raised its price target to $6 from $2.50.......

  • Athersys (NASDAQ:ATHX) expects to complete enrollment by the end of the summer in a Phase 2 clinical trial of its MultiStem cell therapy in about 140 moderate to moderately-severe ischemic stroke patients, with data to be released before year end.

    “If we get the results we’re looking for, this could have a dramatic impact on stroke medicine and greatly improve treatment for more severe stroke patients,” chairman and CEO, Gil Van Bokkelen, says in an interview with BioTuesdays

    Cleveland-based Athersys is developing MultiStem for the treatment of conditions in the cardiovascular, neurological, inflammatory and immune disease areas.

    MultiStem is a biologic product manufactured from human stem cells obtained from adult bone marrow or other nonembryonic tissue sources. The stem cell product can be expanded on a large scale for future use and stored in frozen form until needed....

    See BioTuesdays for rest of this week's feature article on ATHX

  • Ladenburg Thalmann has initiated coverage of CombiMatrix (NASDAQ:CBMX) with a “buy” rating and price target of $3.40. The stock closed at $2.77 on Thursday.

    “We view CombiMatrix as an emerging leader in prenatal chromosomal microarray testing and products of conception for miscarriage management,” writes analyst Kevin DeGeeter.

    See BT for rest of brief....

  • CombiMatrix’s (NASDAQ:CBMX) strategic shift at the end of 2012 to focus its chromosomal microarray testing platform in the areas of prenatal genetics and pediatric development disorders is gaining traction with patients, physicians and payors.

    “We are a vastly different company from a year ago,” Mark McDonough, president and CEO, says in an interview with BioTuesdays. “We have a sharper focus, with millions more patients covered for microarray testing and numerous leading labs and physician groups now on board.”

    The Irvine, CA-based company specializes in miscarriage analysis, prenatal testing and pediatric genetics at its CLIA-approved lab. “We offer DNA-based testing for the detection of genetic abnormalities beyond what can be identified through traditional methods,” he adds.

    ....see BioTuesdays for the rest of tokay's feature on CBMX

  • MRI Interventions’ ClearPoint changing brain surgery paradigm - see BT for this week's feature article.

  • See site for this week's feature on ADXS

  • Boston Therapeutics (OTCQB:BTHE) hopes to begin a pivotal Phase 3 trial, by the second or third quarter of 2014, of a chewable tablet that is designed to be taken before meals to reduce post-meal elevation of blood glucose in Type 2 diabetics.

    “Our PAZ320 drug is a potential adjunct to metformin in patients living with Type 2 diabetes,” CEO David Platt says in an interview with BioTuesdays. “We believe it is important to better control glucose levels throughout the day, given the many complications that stem from uncontrolled diabetes.”

    See BT for rest of article……..

  • William Blair & Co. has initiated coverage of Novadaq Technologies (NASDAQ:NVDQ; TSX:NDQ) with an “outperform” rating and “aggressive growth” company profile, ahead of the company’s annual investor meeting in New York on Monday.

    “We believe this could be a positive catalyst for the stock and expect the company will discuss several of its developing opportunities with investors,” writes analyst Margaret Kaczor.

    These includes the opportunity for Luna, its newly launched wound care product, compelling usage and clinical results within surgery, specifically general surgery and gynaecology, and the financial impact of signing its recent international distributor agreement with Swissray Asia.

    Ms. Kaczor said Novadaq is the only company on the domestic market with a fluorescence imaging technology for use during surgery and diagnostic imaging. “We believe that the company is in only its first stage of growth as it works to penetrate the $2 billion-plus long-term market opportunity.”

    She said that supporting the market opportunity for its technology is a “winning formula of compelling clinical data as well as a decline in overall patient care costs through the reduction of surgical complications.”
    Shares of Novadaq closed at $16.20 on Thursday. She said that at eight times her 2015 sales target of $89-million, up 70% year-over-year, the stock trades above other fast-growing medical technology names. Her “outperform” rating is based on her belief that “adoption will remain strong, which should drive upside to estimates.”

  • November 12, 2013 by leonardzehr · Leave a Comment

    A new sales and marketing venture with a unit of Mission Pharmacal gives DARA BioSciences (NASDAQ:DARA) a formidable leg up in the oncology supportive care sector to address ongoing areas of medical need.

    A 20-person national sales team contracted from Mission’s Alamo Pharma Services will promote DARA’s products, including Soltamox, Gelclair, and Bionect, as well as three Mission products—Ferralet 90 for anemia, BINOSTO for osteoporosis, and Aquoral for chemotherapy/radiation therapy-induced dry mouth. The Alamo sales reps will work under the direction of two DARA sales managers.

    “This dedicated sales force can provide a formidable product portfolio that addresses many of the common challenges and side effects that cancer patients deal with on a daily basis, including oral mucositis, loss of bone density, radiation dermatitis, dry mouth, anemia, and long-term adherence to tamoxifen,” DARA’s CEO and CMO, Dr. David Drutz, says in an interview with BioTuesdays........

    ....See BioTuesdays for rest of this week's feature article...

  • November 1, 2013 by stephenkilmer · Leave a Comment

    Stifel Nicolas has initiated coverage of TherapeuticsMD (NYSE MKT:TXMD) with a “buy” rating and $8 price target, saying the company has three products set to deliver data catalysts and potential approvals every six months starting in late 2015. The stock closed at $4.22 on Thursday.
    “We believe the TherapeuticsMD portfolio represents the first innovation the hormone market has seen in nearly 10 years and could fill a very important void that was left in hormone replacement therapies (HRT) since the NIH-sponsored Women’s Health Initiative clipped the opportunity,” writes analyst Annabel Samimy.
    “With new research supporting its effort and a market that has been left fragmented, under-promoted, and served primarily by the unregulated compounding market, we believe the environment is ripe for TherapeuticsMD’s offering,” she added.
    The annual compounding market for HRT is currently estimated at over $1.5-billion, while the market for regulated branded and generic products has fallen to about $500-million.
    Ms. Samimy said the FDA and legislators are now putting in place major restrictions to this compounding market, leaving an open door for TherapeuticsMD to introduce the first clinically-studied, well-regulated bioidentical combination HRT as a leading alternative.
    “We see a potential launch in late 2016, with a conservative peak of $236-million” in sales, she added.
    She said the company also has developed a low-dose progesterone for secondary amenorrhea, which potentially offers a better side-effect profile, and could launch in late-2015. This would be followed in mid-2016 by an estradiol vaginal suppository, providing ease of administration and lower systemic exposure. She pegs peak sales at $139-million and $53-million, respectively.

  • NeoStem (NASDAQ:NBS) is on track to complete enrollment later this year in a Phase 2 clinical trial of a bone marrow-derived cell therapy to treat patients for acute myocardial infarction, with a data readout six-to-eight months later.

    “AMR-001 represents the first compound in a class of cell therapies to have a highly defined cell population and an identified biologically effective therapeutic dose, both of which tie back to the biological mechanism of action that the outcomes of the current study are intended to demonstrate,” chairman and CEO Dr. Robin Smith says in an interview with BioTuesdays.

    Dr. Smith explains that NeoStem’s AMR-001 drug candidate brings a natural repair system, consisting of enriched CD34+ cells, to the heart in order to preserve heart function following a stent placement in patients with a type of heart attack known as ST segment elevation myocardial infarction (STEMI).

    ….see BIoTuesdays for rest of article….

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