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Celldex Therapeutics, Inc. Message Board

buymois 16 posts  |  Last Activity: Jul 2, 2014 1:53 PM Member since: Feb 17, 2006
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  • Reply to

    One Million Shares Traded

    by j20tower Jul 2, 2014 10:31 AM
    buymois buymois Jul 2, 2014 1:53 PM Flag

    You are right, but don't blame the individual Marines and Army ground pounders who were doing their best (most of the time) to help you out in a pretty much hopeless situation. The US government did bring shame on us the way we handled the withdrawal which precipitated the subsequent chaos and human disaster.

  • buymois buymois Jun 25, 2014 3:33 PM Flag

    You've heard perhaps the phrase "the enemy of my enemy is my friend?" Look what the Iraq mess is now steering us towards - getting into cahoots with Iran and Syria! You don't think Saddam was capable of using Al Qaeda? I think he was capable of doing pretty much anything that would hurt us. He was tossing sand in our face with constant violations of the truce agreement after all. We didn't care much about Saddam gassing the Kurds (well, we cared, but we weren't going to do anything overtly about it) before 9/11, but after 9/11 we had to consider the expanded possibilities. Not sure I would have gone into Iraq either, but I think there was a case to be made, and it's not as simple as you make it out to be.

  • buymois buymois Jun 25, 2014 3:02 PM Flag

    You are using hindsight. What you were thinking on September 12, 2011? We had gone to war with Iraq when Saddam invaded Kuwait. He had used WMD on his own people. He had a known nuclear program at one time. He claimed he had WMD. He hated us, and if he had what he said he had and our (faulty) intelligence told us he had, many thought that the risk of him passing off WMD to Al Qaeda to be used against us was a real possibility.

  • buymois buymois Jun 25, 2014 2:36 PM Flag

    Sept 11th occurred just 7 months into GWB's tenure. It was a more devastating attack on us than Pearl Harbor and we really didn't know how to get at the enemy. With Pearl Harbor at least we knew where to look for the enemy. I submit that not many people would have been prepared to deal with this situation. Maybe GWB overreacted, but if you remember the time, I don't think too many people thought so. Hindsight is 20-20. What would you have done?

  • Reply to

    After Hours Trades

    by maximus06906 Jun 20, 2014 5:03 PM
    buymois buymois Jun 20, 2014 7:46 PM Flag

    OPEX account balancing?

  • buymois buymois Jun 16, 2014 2:44 PM Flag

    Iraq/Iran/Bush/Obama. You can't make this stuff up!

  • buymois buymois Jun 13, 2014 6:01 PM Flag

    I say that with some admiration, because as I remember it was some b.s. investigation about her over billing her clients. Don't all lawyers over bill their clients?

  • buymois buymois Jun 13, 2014 5:03 PM Flag

    Right out of Hillary's playbook. Remember her Rose Law Firm's billing records? They were subpoenaed but she did not produce them because they supposedly were lost. The day after the statute of limitations expired they miraculously showed up in her office. That was an amazing "in your face" stonewall effort.

  • Reply to

    Now All Hell Breaking Loose In Iraq

    by j20tower Jun 13, 2014 7:48 AM
    buymois buymois Jun 13, 2014 3:34 PM Flag

    BHO was dealt a bad hand on Iraq because of the Bush administration's intelligence error on WMD. However, it should be noted that Saddam was bragging at the time that he did indeed have WMD. But once in, and with the surge seeming to work, BHO needed to be smarter about our withdrawal. He telegraphed the withdrawal so the terrorists and Al Maliki could wait out our departure. And, of course, when we left no residual force, Al Maliki was free to screw things up by shutting out the Sunni's from government. participation. Two bad decisions - one from each side. Predictable results.

  • Reply to

    I Guess Us Bag Holders

    by j20tower Jun 10, 2014 1:30 PM
    buymois buymois Jun 11, 2014 12:25 AM Flag

    You seemed to be a schizophrenic investor/trader. You could go from sounding like a true believer long to a convinced short - and all in the same day. It was hard to take you seriously. It is certainly a good idea to buy when LV says he is buying. He doesn't always pick the lowest price to get in, but if you have a long term view, you will do well following him. He is not a trader.

    Sentiment: Strong Buy

  • Reply to

    I Guess Us Bag Holders

    by j20tower Jun 10, 2014 1:30 PM
    buymois buymois Jun 10, 2014 6:39 PM Flag

    Tacke,
    My first purchase of CLDX was made in the runup to ASCO in 2010. I bought 1,000 shares at about $7.50. After ASCO 2010, CLDX started on a downward trajectory that found it selling for $2.10 on October 3, 2011 (when Fraz bought all of his shares, I suppose). Along the way their big pharma partner dumped them and things looked pretty bleak. Obviously, I was pretty bummed out that it didn't immediately shoot to the moon, instead it cratered. However there were believers in the science and pipeline who encouraged me to continue to purchase shares. I got quite a few shares in the $3 and $4 range (I'm not as skilled as Fraz in catching the absolute low). So I ended up with 18,000 shares with an average of about $4.40. Along the way up to $38, I sold a few (last sale was 1,000 shares at $37.25 - again I was not smart enough to sell all of my shares at $37.25). However I still own 15,000 shares at a pretty low average. One of my buddies heard me talking about CLDX and bought 1,000 shares at $31 as it backed off from the $38 high. He was pretty upset when CLDX started to tumble. He bought another 500 at $23 - and continued to grumble when it continued to slide. However, he ended up buying another 8,500 shares in the $12 - $13 range and now has 10,000 shares at an average cost of about $16. I think Fraz calls this his proprietary averaging down method that MBB disparages so much. However, I am a believer in the method if company management is competent, experienced and proven in the field; the science is sound; and the pipeline is deep. I think CLDX hits all these criteria, so in this case the averaging down method seems to be working so far. I'm not a trader. I can wait for several years for this to blossom. Have patience, young man!

    Sentiment: Strong Buy

  • Reply to

    SEC filing alerts

    by tina_astoria Jun 5, 2014 4:37 PM
    buymois buymois Jun 5, 2014 5:48 PM Flag

    Nice! Marucci has a $476,000 paper gain today on the 280,000 unvested incentive stock options he was granted yesterday. I hope Marucci and his management team make many millions on the 707,000 options granted to them yesterday under the company's incentive stock option plan.

    Sentiment: Strong Buy

  • Reply to

    Abstracts - Maybe Long Can Give Some Insight

    by buymois May 14, 2014 8:22 PM
    buymois buymois May 14, 2014 8:39 PM Flag

    Wouldn't copy entire abstract, so not posting the other abstract. You can search on Celldex at
    abstracts dot asco dot org.

  • Author(s): Stephen Maxted Ansell, Donald W. Northfelt, Ian Flinn, Howard A. Burris, Shira Naomi Dinner, Victor Manuel Villalobos, Branimir I. Sikic, Matthew Hiram Taylor, Lana Pilja, Thomas R. Hawthorne, Michael Jay Yellin, Tibor Keler, Thomas A. Davis; Mayo Clinic, Rochester, MN; Mayo Clinic, Scottsdale, AZ; Sarah Cannon Research Institute/Tennessee Oncology, PLLC, Nashville, TN; Northwestern University Robert H. Lurie Comprehensive Cancer Center, Chicago, IL; Stanford Cancer Institute, Stanford, CA; Knight Cancer Institute,Oregon Health and Science University, Portland, OR; Celldex Therapeutics, Inc., Hampton, NJ

    Abstract Disclosures

    Abstract:

    Background: CD27, a member of the TNF receptor superfamily, is a co-stimulatory molecule that regulates T cell activation, survival, and memory responses through interaction with a tightly regulated ligand, CD70. CDX-1127 is an anti-CD27 human antibody shown to activate human T cells when combined with T cell receptor stimulation, and mediate anti-tumor activity in human CD27 transgenic mice challenged with syngeneic tumors. Methods: In a 3+3 dose-escalation (DE), patients (pts) with advanced B-cell lymphoma received CDX-1127 (0.1, 0.3, 1.0, 3.0 or 10 mg/kg IV) as a single dose with 28-day observation, followed by up to 5 treatment cycles (4 weekly doses / Day 85 restaging), until progression. Results: 19 pts (3 Hodgkin (HL), 5 follicular, 9 diffuse large B-cell, 2 unspecified non-Hodgkin) have received CDX-1127. DE has exceeded 3 mg/kg with no DLT; enrollment at 10 mg/kg is ongoing. Treatment-related toxicity, generally Grade 1-2, included fatigue, nausea, decreased appetite and anemia. A pt with Stage IV Hodgkin lymphoma who had previously failed chemotherapy, autologous stem cell transplant, and brentuximab vedotin experienced a complete response (CR) and remains in remission at 8.6+ months. IHC analysis of archived tumor for the 3 HL pts showed CD27-negative reed-sternberg cells and CD27-expressing infiltrating lymph

    Sentiment: Strong Buy

  • Reply to

    Overbought short term.

    by mhectic1977 May 14, 2014 12:16 PM
    buymois buymois May 14, 2014 3:04 PM Flag

    Wait till you see what's behind door number 2.

    Sentiment: Strong Buy

  • last June (or thereabouts) when Cramer said to buy and hold? Maybe his hedge fund buddies didn't like all of the little Cramerites getting part of the action and they needed to shake them out. Anyhow, I feel like I've been waterboarded the last couple of months by whatever/whoever is causing this ridiculous decline.

    Sentiment: Hold

CLDX
14.12-0.19(-1.33%)Jul 10 4:00 PMEDT

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