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Vical Incorporated Message Board

camptownn 1 post  |  Last Activity: Nov 5, 2014 9:17 AM Member since: Oct 28, 2003
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  • camptownn camptownn Nov 5, 2014 9:17 AM Flag

    AnGes. In 2005, we granted an exclusive worldwide license to AnGes for use of our core DNA delivery technology in the development
    and commercialization of DNA-based products encoding hepatocyte growth factor, or HGF, for cardiovascular applications. HGF is a human
    protein that promotes angiogenesis. AnGes is developing Collategene , a DNA-based delivery of HGF for indications related to PAD, a severe
    condition caused by blockage of blood vessels feeding the foot and lower leg.
    AnGes has obtained a Special protocol assessment from the FDA for a Phase 3 clinical trial of Collategene for patients with Critical limb
    ischemia, but has not yet commenced the study. In December 2013, the last of the patents we licensed to AnGes expired, and as a result the
    license agreement expired in accordance with its terms.

VICL
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