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AVEO Pharmaceuticals, Inc. Message Board

crecy_war_knight 475 posts  |  Last Activity: 2 hours 36 minutes ago Member since: Jan 25, 2007
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  • Reply to

    Uli got $208,800

    by crecy_war_knight Mar 26, 2015 2:52 PM
    crecy_war_knight crecy_war_knight 2 hours 36 minutes ago Flag

    It will be interesting how it all plays out. Do you think Uli is gone forever? I don't think we have see the last of Uli at least i will be surprised if we don't here about some legal action later.

  • crecy_war_knight crecy_war_knight 3 hours ago Flag

    used http://acronyms.thefreedictionary.com/ CMO and CMC

  • Certified Management Consultant and Contract Manufacturing Organisation....is this correct? This is my guess from looking around on the net. The guys that will consult regarding the manufacturing systems = CMC. The site where the drug is made = CMO. Is this correct? My guess also is that the term "certified" would be certified by the FDA...is that correct?

  • Reply to

    Uli got $208,800

    by crecy_war_knight Mar 26, 2015 2:52 PM
    crecy_war_knight crecy_war_knight 4 hours ago Flag

    I don't think so since any new CEO might not go along with that. He ( don't forget a "she" is possible too) may wish to proceed in a different manner regarding Davis & Mills.

  • Reply to

    Uli saw the writing on the wall!

    by nobleonetoo Mar 26, 2015 2:23 PM
    crecy_war_knight crecy_war_knight 15 hours ago Flag

    SELL the news.

  • Reply to

    crecy_war_knight

    by chxfhx 21 hours ago
    crecy_war_knight crecy_war_knight 16 hours ago Flag

    Thanks so much.

  • Reply to

    My thoughts

    by doc_3377 Mar 26, 2015 7:08 PM
    crecy_war_knight crecy_war_knight 22 hours ago Flag

    Perhaps our conversation would stimulate the hallucinating board members. By the way I worked for KP here in Calif. x 30 yrs.

  • Reply to

    To all naysayers

    by chxfhx Mar 18, 2015 9:38 PM
    crecy_war_knight crecy_war_knight 23 hours ago Flag

    chxfhx, ......ri66 keeps bumping this post over and over again. Because its not his original post I do see it even though I have ri66 on IGNORE. So I am going to put you on IGNORE starting tomorrow to completely wipe ri66 off my view of the message board. I feel bad about it and hesitated to take this action for the last few days. I guess you could remove this post and be done with it and that would solve the problem, but I am not asking you to do that only saying so I don't have to place you on IGNORE.

  • Reply to

    ACAD review

    by crecy_war_knight Mar 26, 2015 10:32 PM
    crecy_war_knight crecy_war_knight Mar 27, 2015 2:21 PM Flag

    I got many of those losers on Ignore, including ri66 who just keeps bumping up his posts ad nauseam. Over and over...geez, the guy has no imagination. Contributes absolutely NOTHING to the board. Basically he has the I.Q. of a copy machine. Got him on Iggy so I never see any of his original posts.

  • Reply to

    ACAD review

    by crecy_war_knight Mar 26, 2015 10:32 PM
    crecy_war_knight crecy_war_knight Mar 27, 2015 1:16 PM Flag

    That too, we need new blood, my suggestion a week or so ago is Mr. Pyott former CEO of Allergan which recently got bought out. He negotiated the deal with Actavis. He is at the top of the Biotech game and would be a sure winner for ACAD. I don't know if he would be willing to come over to Acadia. But he does live not far from Acadia. We must have someone of his caliber to lead this company. At any point, Davis is out as CEO as far as I am concerned. Davis will be lucky if he and Mills don't get let go. More of the same would not be tolerated by the BOD.

  • Reply to

    A little TA?

    by crecy_war_knight Mar 26, 2015 12:00 PM
    crecy_war_knight crecy_war_knight Mar 27, 2015 12:15 PM Flag

    At this point the Morning Star ( "Raindrop "), seems to be confirmed. Bears losing their control.

  • crecy_war_knight by crecy_war_knight Mar 27, 2015 9:55 AM Flag

    Support/Resistance
    Type Value Conf.
    resist. 45.88 2
    resist. 39.91 2
    resist. 38.29 4
    resist. 36.55 4
    resist. 34.54 7
    resist. 32.98 2
    resist. 30.83 5
    supp 28.65 6
    supp 26.57 2
    supp 25.52 2
    supp 22.34 2

    Recent CandleStick Analysis
    Very Bullish
    Date Candle
    Mar-26-2015 DOJI

  • Reply to

    My thoughts

    by doc_3377 Mar 26, 2015 7:08 PM
    crecy_war_knight crecy_war_knight Mar 27, 2015 1:43 AM Flag

    oh ...NP = No Problem.

  • Reply to

    My thoughts

    by doc_3377 Mar 26, 2015 7:08 PM
    crecy_war_knight crecy_war_knight Mar 27, 2015 1:42 AM Flag

    I thought I wrote GP.

  • Reply to

    ACAD review

    by crecy_war_knight Mar 26, 2015 10:32 PM
    crecy_war_knight crecy_war_knight Mar 27, 2015 1:40 AM Flag

    Well I believe the BOD will see he is one of the reasons why the NDA submission date was delayed again and so is Mills. I mean they were part of the top 3 in the Leadership Team that failed us. So I think that knocks him right off the short list at some point.

  • Reply to

    My thoughts

    by doc_3377 Mar 26, 2015 7:08 PM
    crecy_war_knight crecy_war_knight Mar 26, 2015 10:37 PM Flag

    OUR POSTS GOT REMOVED, NP

  • crecy_war_knight by crecy_war_knight Mar 26, 2015 10:32 PM Flag

    We now have the BOD slot filled, Mr Soland, and most likely the short list for the CEO position is close to being completed. I would say a few more weeks for the new CEO to be announced. It won't be Davis. Pimavanserin is ONE OF A KIND, FIRST IN ITS CLASS drug to treat Parkinson's Disease Psychosis (PDP). And ACAD owns the World Wide Rights to it. The FDA has already reviewed the Phase3 research data and given ACAD thumbs up to proceed with the New Drug Application and has give Pima " Breakthrough Therapy Designation " USA sales will be over 1.1 BILLION and European Union will be well over a Billion as well. There are several other ongoing studies.. The manufacturing arm of the NDA is getting the close attention it should of had last year- it will take some time for new directors & CMO 's to get the systems ready & on line for the FDA evaluations. ..Review the catalyst list-

    1) Replacing the CEO with a new Great Leader who can led us to Drug Approval and move the company forward.
    2) Possible Partnership with a MAJOR drug company that will assure the NDA will meet and exceed all the FDA standards.
    3) 60 days for the FDA (Food and Drug Administration ) to accept the application by about Q1 2016.
    4) Upon potential acceptance, FDA could also grant priority review.
    5) With priority review, six months pdufa date (Prescription Drug User Fee Act ), without, 10 months. Best guess is July to Oct 2016.
    6) EU ( European Union ) filing 6- 9 months post FDA filing. I am thinking not so long for this, say Q4 2016.
    7) ADP enrollment (019 study) complete by 2015 Q4 and data by about Q2 2016
    8) Schizophrenia maintenance trial to commence 2nd half of 2015.
    9) other, eg Autism.
    DATES ARE SUBJECT TO DEBATE OR CHANGE AND THEY DO GET DELAYED- this is not uncommon in the world of Biotech. You have to roll with the punches

  • Reply to

    Uli got $208,800

    by crecy_war_knight Mar 26, 2015 2:52 PM
    crecy_war_knight crecy_war_knight Mar 26, 2015 9:05 PM Flag

    208K is basically a slap in the face, because consider the MK went from about 4.5Billion to 3Billion in just a few days.

  • Reply to

    My thoughts

    by doc_3377 Mar 26, 2015 7:08 PM
    crecy_war_knight crecy_war_knight Mar 26, 2015 8:59 PM Flag

    This is exactly what was recommended for me to give several of my patients, Seroquel and I think it was a neurologists although its been so long I can't remember all the details. I retired as a GP back in 2013. As I recall I had a difficult time finding the dose that would work because of excessive sedation with I believe Seroquel ? Also there was some discussion about doing an LP, which I don't believe was done, I forget why. Then when I called the ER the ER asked me if I could do it in my office. Of course I declined and can't remember if he went back to the ER to do the LP.

  • Reply to

    My thoughts

    by doc_3377 Mar 26, 2015 7:08 PM
    crecy_war_knight crecy_war_knight Mar 26, 2015 7:35 PM Flag

    You get the call from a GP that a patient with PD is having some new Sx of hallucinations...the patient is evaluated in the ER and nothing significant is out of sorts (no infections, labs all ok , CT/MRI normal for age etc) except he has PDP is the ER Dx. Asume he is on type PD meds. What is your recommendation ?

AVEO
1.37+0.010(+0.74%)Mar 27 4:00 PMEDT