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Array BioPharma Inc. Message Board

crecy_war_knight 644 posts  |  Last Activity: 4 hours ago Member since: Jan 25, 2007
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  • Reply to

    MM - typical money changers

    by crecy_war_knight May 31, 2016 1:18 PM
    crecy_war_knight crecy_war_knight Jun 1, 2016 12:17 PM Flag

    You sold it after the positive data correct? You didn't want to wait for the NDA correct.

  • Reply to

    MM - typical money changers

    by crecy_war_knight May 31, 2016 1:18 PM
    crecy_war_knight crecy_war_knight May 31, 2016 1:53 PM Flag

    Take the money and run.

  • Reply to

    MM - typical money changers

    by crecy_war_knight May 31, 2016 1:18 PM
    crecy_war_knight crecy_war_knight May 31, 2016 1:47 PM Flag

    Great find for the believers. I took a look it this am. In retrospect even after the positive data release I would not have bought it. Its not the type of biotech that interests me. Very small sector of patients, maybe ? 10K/yr. And before the data release I wouldn't have bought it either, difficult cancers, AML as I recall. Thing is, it is a good match for JAZZ, an easy buy, but Total Cash 980 Mill -( they could never buy ACAD). A low hanging fruit. Also the drug is not FDA approved yet. But still those who are in, congrats.

  • Reply to

    MM - typical money changers

    by crecy_war_knight May 31, 2016 1:18 PM
    crecy_war_knight crecy_war_knight May 31, 2016 1:20 PM Flag

    then...ugh spelling, don't tell my wife.

  • crecy_war_knight by crecy_war_knight May 31, 2016 1:18 PM Flag

    It is what it is, the "firm" is just the money changer, so they shake the tree every now and them to drum up some business. I didn't see many complaints when it ran up like 10 days in a row. Better get use to it. I mean they get FDA approved and the stock goes down, Ugh! Now launch and 13 cents up, not a great response-the IBB having a nice day though. Basically we are way Over Bought and bumping up against some moderate Resistance. We could see some pull back. Again if you use Stops you will lose your shares.

  • Reply to

    The Market Making?

    by thehorse2002 May 31, 2016 12:21 PM
    crecy_war_knight crecy_war_knight May 31, 2016 12:34 PM Flag

    pedigree...?

  • crecy_war_knight by crecy_war_knight May 31, 2016 12:28 PM Flag

    It won't be much, about 1 month of sales.

  • Reply to

    America --You Know Have Nuplazid

    by hardcider65 May 31, 2016 10:20 AM
    crecy_war_knight crecy_war_knight May 31, 2016 10:50 AM Flag

    Great news...( --You now have Nuplazid )....interesting the company announced launch would be in June...I figured about June 15. But not complaining just think its odd.

  • Reply to

    Have a great Memorial Day

    by crecy_war_knight May 27, 2016 4:29 PM
    crecy_war_knight crecy_war_knight May 30, 2016 12:00 PM Flag

    Well said. Thanks.

  • crecy_war_knight crecy_war_knight May 30, 2016 11:54 AM Flag

    Metabolic Changes: Atypical antipsychotic drugs have been associated with metabolic changes including hyperglycemia/diabetes mellitus, dyslipidemia, and weight gain. Clinical monitoring is recommended.

    Leukopenia, Neutropenia, and Agranulocytosis: Leukopenia, neutropenia, and agranulocytosis have been reported with antipsychotic use. Perform complete blood count (CBC) in patients with a pre-existing low white blood cell count (WBC) or a history of leukopenia or neutropenia. Consider discontinuing REXULTI if a clinically significant decline in WBC count occurs in the absence of other causative factors.

    Orthostatic Hypotension and Syncope: REXULTI should be used with caution in patients with known cardiovascular disease, cerebrovascular disease, or conditions which would predispose them to hypotension.

    Seizures: Use cautiously in patients with a history of seizures or with conditions that lower the seizure threshold.

    Body Temperature Dysregulation: Appropriate care is advised for patients who may exercise strenuously, be exposed to extreme heat, receive concomitant medication with anticholinergic activity, or be subject to dehydration.

    Dysphagia: Esophageal dysmotility and aspiration have been associated with antipsychotic drug use. REXULTI should be used with caution in patients at risk for aspiration pneumonia.

    Potential for Cognitive and Motor Impairment: REXULTI may have the potential to impair judgment, thinking, or motor skills. Patients should not drive or operate hazardous machinery until they are certain REXULTI does not affect them adversely.

    Alcohol: Advise patients to avoid alcohol while taking REXULTI.

    Concomitant Medication: Administer half the dose of REXULTI with strong CYP2D6 or CYP3A4 inhibitors. Administer a quarter of the dose with strong/moderate CYP2D6 inhibitors or known CYP2D6 poor metabolizers taken with strong/moderate CYP3A4 inhibitors. Double the dose with strong CYP3A4 inducers over 1 to 2 weeks.

    In clinical trials examining the adjunctive use of REXULTI in the treatment of MDD, dosage was not adjusted for strong CYP2D6 inhibitors (e.g., paroxetine, fluoxetine). CYP considerations were already factored into general dosing recommendations for MDD. Thus, REXULTI may be administered without dosage adjustment in these patients.

    Most commonly observed adverse reactions: Adult patients with major depressive disorder (adjunctive treatment to antidepressant therapy; ≥5% incidence and at least twice the rate of placebo for REXULTI vs. placebo, respectively): akathisia (9% vs. 2%) and weight increase (7% vs. 2%). Adult patients with schizophrenia (≥4% incidence and at least twice the rate of placebo for REXULTI vs. placebo, respectively): weight increased (4% vs. 2%).

    Dystonia: Dystonia may occur in susceptible individuals during the first days of treatment and at low doses.

    Pregnancy: Non-Teratogenic Effects – Neonates exposed to antipsychotic drugs during the third trimester of pregnancy are at risk for extrapyramidal and/or withdrawal symptoms following delivery. REXULTI should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

    Lactation: It is not known if REXULTI is excreted in human breast milk. Discontinue the drug or nursing, taking into account the importance of the drug to the mother.

    INDICATIONS

    REXULTI is indicated for:

    Use as an adjunctive therapy to antidepressants in adults with major depressive disorder
    Treatment of schizophrenia in adults

  • crecy_war_knight crecy_war_knight May 30, 2016 11:32 AM Flag

    Uses

    This medication is used to treat certain mental/mood disorders (such as schizophrenia, depression). Brexpiprazole helps you to think more clearly, feel less nervous, and take part in everyday life. It may also help to decrease hallucinations (hearing/seeing things that are not there). In addition, this medication may improve your mood, sleep, appetite, and energy level. Brexpiprazole is a psychiatric medication that belongs to the class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain.

  • IMPORTANT SAFETY INFORMATION AND INDICATIONS for REXULTI® (brexpiprazole)
    IMPORTANT SAFETY INFORMATION
    Increased Mortality in Elderly Patients with Dementia-Related Psychosis

    Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death compared to placebo. REXULTI is not approved for the treatment of patients with dementia-related psychosis.

    Suicidal Thoughts and Behaviors
    Antidepressants increase the risk of suicidal thoughts and behaviors in patients aged 24 years and younger. All patients on antidepressant therapy should be monitored and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Also, families and caregivers should be advised to closely observe these patients and communicate with the prescriber. REXULTI is not approved for use in pediatric patients with depression.

    See Full Prescribing Information for complete Boxed WARNING.
    Contraindication: Known hypersensitivity reaction to REXULTI or any of its components. Reactions have included: rash, facial swelling, urticaria and anaphylaxis.

    Cerebrovascular Adverse Events, Including Stroke: In placebo-controlled trials with risperidone, aripiprazole, and olanzapine in elderly patients with dementia, there was a higher incidence of cerebrovascular adverse reactions (stroke, TIA), including fatalities, compared to placebo-treated patients.

    Neuroleptic Malignant Syndrome (NMS): A potentially fatal complex sometimes referred to as NMS has been associated with the administration of antipsychotic drugs. Manage with immediate discontinuation of antipsychotic drugs and other drugs not essential to concurrent therapy, intensive symptomatic treatment and medical monitoring.

    Tardive Dyskinesia (TD): REXULTI should be prescribed in a manner most likely to minimize the occurrence of TD. If signs and symptoms of TD appear, drug discontinuation should be considered.

    Metabolic Changes: Atypical antipsychotic drugs have been ass

  • Reply to

    Have a great Memorial Day

    by crecy_war_knight May 27, 2016 4:29 PM
    crecy_war_knight crecy_war_knight May 29, 2016 5:03 PM Flag

    OK thanks, I always wonder how you expert traders play the stocks.

  • Reply to

    Have a great Memorial Day

    by crecy_war_knight May 27, 2016 4:29 PM
    crecy_war_knight crecy_war_knight May 29, 2016 2:14 PM Flag

    I appreciate that. Welcome.

  • Reply to

    Have a great Memorial Day

    by crecy_war_knight May 27, 2016 4:29 PM
    crecy_war_knight crecy_war_knight May 29, 2016 12:18 PM Flag

    who wrote it?

  • Reply to

    Have a great Memorial Day

    by crecy_war_knight May 27, 2016 4:29 PM
    crecy_war_knight crecy_war_knight May 28, 2016 7:48 PM Flag

    If you click on the chart once and look to the left check out "Profile" and go to the company web site. Also click on Key Stats, Headlines etc. If you click on the chart twice then you got to the big chart ...start to become familiar with the indicators, candlestick charts, moving averages etc. If you look near anyones name you will see "Flag"...you can use this to IGNORE bashers and dimwits.

  • Reply to

    Have a great Memorial Day

    by crecy_war_knight May 27, 2016 4:29 PM
    crecy_war_knight crecy_war_knight May 28, 2016 2:16 PM Flag

    Get the book, read about those guys.

  • crecy_war_knight by crecy_war_knight May 27, 2016 4:29 PM Flag

    If you want to read a good military book, there is a book titled " Stealth Patrol: The Making Of A Vietnam Ranger " on Amazon written by my buddy Bill Shanahan.

    N co 75th Infantry, Long Range Reconnaissance Patrol (LRRP), 173rd Airborne Brigade. '68-69

  • Reply to

    Biotech news....

    by rosettawest May 27, 2016 7:50 AM
    crecy_war_knight crecy_war_knight May 27, 2016 4:22 PM Flag

    Well I am glad its behind us. And I thankful it turned out as well as it did.

  • Reply to

    Biotech news....

    by rosettawest May 27, 2016 7:50 AM
    crecy_war_knight crecy_war_knight May 27, 2016 3:38 PM Flag

    Uli was the CEO- the buck stops with him and he dropped the ball, he's lucky he didn't end up in court or investigated by the SEC. He totally screwed up the company and was handed his hat. Lucky him. The BB didn't steal anything. They were perfectly happy with the NDA " on track " like everyone else. I am sure they would have preferred the whole thing had never have happened.

ARRY
3.45-0.13(-3.63%)Jun 24 4:00 PMEDT