Need a job? - Harmonix Music lists the need for at least 3 "software engineers" for animation, gameplay, & graphics Plus in the publishing dept they want an intern & a web-developer _ MCZ seems not to post openings
_ I've looked from time to time for the heck of it _ good post by the way
Yes Hope I did read 1 or 2 posts on RB of yours _ just didn't know until now if you were considering the whole mix of our mcz _ it will be interesting to see how the 2nd half of the year's economy & political events effect the general stock market and how that plays on the mcz pps _ From cross referencing the sources I like on said issues the probabilities lean very strongly to the downside from Sept on _ we shall see "hopefully"
Where mcz has been still plays with their present and future _ Comments, not reviews, are tainted with bad memories _ And there are those comments and reviews stating where a product like the newest keyboard falls short with too high of a price plus it is not mechanical _ The lemonade just doesn't taste that great today _ The m.o.j.o. in their lhas a bad after taste along with a couple other things _ So will the added RB flavor plus the couple other half way descent sellers be enough to really make it good OR will it stay close to zero on the balance sheet just straddling from one side to the other of profit and loss quarter after quarter for let's say the next 18 months??? Given all that makes up mcz right now is there really an item, items / goods and or a deal or 2 or 3 that really will be the factor(s) that make this ride up to like $1.50 or wherever ?
When reading the complete article the title is misleading as media plays their typical games _ Not to say it also makes a reality check with the new found data _ A little definition on their key point - The tau protein stabilizes the structure within the nerve cells that the cells need to divide, carry substances and use for support. If this protein becomes abnormal, it will form twisted fibers inside of the nerve cells and destroy them, which causes various neurological diseases. An abnormal tau protein can cause tangles inside the nerve cells of a person with Alzheimer's and swollen nerve cells in people who have Pick's disease or corticobasal degeneration.
What is a Tau Protein?
The tau protein is found in all nerve cells and stabilizes the microtubules of the cell; that is, it stabilizes the structure that supports the cell, carries substances within the cell and helps the cell divide. In an article in the April 2004 issue of “Physiological Reviews,” Jesus Avila states if phosphorus attaches to several places on the tau protein, the protein will break off the microtubules and form twisted fibers. These twisted, abnormal fibers can then harm the nerve cells and lead to several disorders, including Alzheimer's disease, Pick's disease and corticobasal degeneration
IF your interested in researching them -
The modern treatment era for multiple sclerosis (MS) began in 1993 with the approval of the first disease-modifying agent. Since then the field has greatly expanded, with 10 therapies currently approved to treat MS. These treatments are effective to reduce relapses and changes on MRI, and slow disability. However, despite these medications some patients continue to have exacerbations, accumulate disability, and develop progressive disease due to partial effectiveness. New molecules with novel mechanisms of action and targets are being explored. Hopefully these agents will yield even greater efficacy without significant safety concerns. As more aggressive therapies are available to treat MS, the goals and expectations of treatment are also likely to change. Some of the emerging therapies, including alemtuzumab, daclizumab, rituximab, ocrelizumab, laquinimod, estriol, 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins), vitamin D, and stem cell transplantation, will be discussed in this chapter. In the future, therapies with different mechanisms may be combined, but this will need to be evaluated in clinical trials. Neuroprotection and repair definitely warrant further study. The future of MS treatment is very exciting, especially as our armamentarium expands. *** I found this article in this extrapolated form - sorry there is no "will be discussed in this chapter" follow along - I'm still looking
got to their website - one way - yahoo syn summary * to profile * see link under "homepage" * on syn site menu on right side list "about us" - it opens up so click the management team - that's one place to start
I'm not a fan of the CCSVI approach even if the 90% stat on iron present _ It's not so much the invasive procedure _ It does not correct what caused it to build up thus leading to the medical condition _ The UBC study seems to be no more credible based on the ending of the last sentence. Until estriol / trimesta studies move further along currently a holistic treatment, though complicated due to the many parts or aspects and how they get tweaked per individual is the most effective plan to my knowledge - and our poster Tina knows much more than I - And by the way it wouldn't surprise me to find out Dr. P. Zamboni invented that ice hockey machine - Best of Make'n SYN $$s
Not today's news, buy another MS info floating out there in the world - More than 90% of people with MS have some malformation or blockage in the veins that drain blood from the brain. Iron builds up in the brain blocking and damaging the crucial blood vessels. As the vessels rupture they allow both the iron itself and immune cells from the bloodstream to cross the blood-brain barrier into the cerebro-spinal fluid. Once the immune cells have direct access to the immune system they begin to attack the myelin sheathing of the cerebral nerves then MS develops. That's his hypothesis. 73% of his 65 MS patience were cured through his surgical method Chronic Cerebro-Spinal Venous Insufficiency including his wife
General info regards myelin health - Myelin sheath degeneration is widely believed to be an autoimmune process in which the white blood cells attack the myelin sheaths as if they were a foreign substance. Stress and malnutrition (poor diet) often precede the onset of symptoms. There is also a hereditary factor involved.
It is currently thought that exposure to a virus or to chemicals or toxic metals may be launching the autoimmune process in susceptible individuals. The levels of mercury in people with MS has been found to be an average of 7 times higher than those in healthy people. Mercury has been shown to bind to the DNA of cells and cell membranes, causing cellular distortion and inhibited cell function. Many experts suspect that mercury poisoning is behind many types of neurological disorders. Some people react to amalgam dental fillings (the chief source of mercury exposure for most people in the United States) with symptoms that are indistinguishable from those of Multiple Sclerosis.
As well, fascinating new research points to a definitive link between food additives such as aspartame and MSG and the development of lesions on the myelin sheath. According to Russell Blaylock, M.D., a Board certified neurosurgeon and author of the book “Excitotoxins: The Taste That Kills” _ *** "The Better Brain Book" by Dr. David Pearlmutter _ "Who's in Control of Your Multiple Sclerosis" by Dr. W. Code _ Contribute to myelin health - heavy metal detox * correct ranges for copper & vit D3 _ take methylcobalomin form of B12, lecithin, acetyl-l-carnitine and the all important need for Glutathione levels to be correct attained through using both liposomal glutathione and non denatured whey protein sources _ My friends sister was 37 in the early '90s when MS took her _ With the unfolding of studies, like trimesta, and info out there from an integrated medicine perspective all the probabilities are extended for a healthy outcome through a positive presence, discipline and
When the CEO position at SYN became open they know they have to make a competitive offer no matter who they chose _ You've probably read this -
"Mr. Riley, a member of the Synthetic Biologics Board of Directors since March 2010 and Chairman of the Board from November 2011 to May 2012, was appointed as the Company’s President and Chief Executive Officer in February 2012. He has more than 20 years of experience in the biotechnology and pharmaceutical industries during which he negotiated numerous worldwide strategic corporate alliances, established joint ventures, and assisted in obtaining venture financings to support product development. Most recently, in addition to serving as Synthetic Biologics' Chairman, where Mr. Riley played an integral role in the formation of the Company¹s recent collaboration with Intrexon Corporation, he served as Managing Director of 526 Ventures, a life science-focused venture consulting firm with a commercial and traditional focus. Prior to this, he was a venture partner with QIC Bioventures Fund, the life science-focused venture component of the $70 billion Australian-based Queensland Investment Corporation (QIC). Over his career, Mr. Riley held senior positions within the mergers & acquisitions and in country management groups at both SmithKline Beecham and Pfizer. Additionally, he served as CFO and VP Corporate Development for Nichols Institute Diagnostics, later acquired by Corning and spun out to Quest Diagnostics, Inc. (NYSE: DGX). Mr. Riley holds a Bachelor of Science degree from Boise State University, completed coursework at UCSF/Berkeley in drug discovery/development and participated in a dual-degree graduate program (MBA/MIM) sponsored by Arizona State University and the Thunderbird School of Global Management." _ ** There are plenty CEO's of publically traded companies that are new to the industry they head and many who have been in their field a long time only to take the top position for the 1st time doing it justice
That would be my 1st reaction _ Sorry to agree with the other posters because the facts show those figures to be in-line with the bio field _ you can find compensation to support your statement but only from a bias gathering of the data _ IF they earn that 75% bonus we better have some profitable smiles on our mugs
Wish it was that easy _ hope your right as I've got my long position _ just not counting those chickens until trimesta data is out _ I'm 50/50 on the results _ just not sold after what happen last time so that pr will be a reality check _ don't you think a deal is unlikely prior to the data?
yea griffin report not there but an earlier pr same day and right below the maxim pr was / is a rec for syn by investors-edge
Syn opened the year at 1.55 closed 2day 2.45 - so what is that a 63% gain _ I'm liking the probabilities as the odds just might favor us here _ It could be a small time window between now and the next PR where the share price goes lower _ And the odds may not be other than 50 / 50
Trimesta partnering pending MRI, new top-line & end point data _ these findings will answer and separate who the partnership candidates will be _ i'm thinking if the data leads away from copaxone and the like( though a slightly more unlikely senario) a partnership deal will be pushed out but happen before the year ends as JR might strongly go this inevitable route sooner than later rather than start tapping that newly increased line of credit, imo _ As for Pertussis we just might be given fast track status towards the end of the year or more likely in the early part of '16 due to the concerns of the WHO and especially the CDC _ All things considered as how busy the PR dept will be during the next 3 months i'd have to say this calls for some shorter term share consumption with the idea of having some extra spending money for these up and coming summer months
Do you have a game plan for investing in syn? _ I ask as it makes a difference on several aspects _ Do you have a goal for an approximate total # of shares you want to own and if so how will you achieve this? - Also what is your exit strategy for those shares? _ That's just for starters - to answer directly @ 2.68 - i'd take a bet within 1 yr you'll have a descent profit like 7 to 10K _ From all i come across the general market will have an extremely poor 2nd half this year and syn will fair out above average if what they have happening turns out favorable _ Best of Make'n $$s
worthy point FP & don's confirm _ though reading the SYN PRs along the way seems Trimesta just might not come about without deeper than anticipated difficulties that seriously test shareholders _ nice we don't have a 1 trick pony here
VG post style & info _ looking forward to it & ditto on J. Douglas _ Have you heard of the dimethyl fumarate studies on-going as an ms treatment _ it is further along than estriol _ if approved syn will take a hit _ this does not mean trimesta is done / not at all - it's just good for syn holders to have some idea on this