It's called Bioprinting human livers & other organs. The previous poster mentions IDRA working on a third generation which is old news. Isis & IDRA are working on forth generation of which educates the public with regard to the problems of the 2nd & 3rd generation of antisense drugs. Hey Stan, where is the ORAL antisense drug that you stated was to be announced soon with ELN in 1999?
BTW, Cramer stated his silly off the cuff remark about Isis the other day. Here is a man that recently stated he likes the work Isis is doing on Crohn's disease. Entertainer Cramer does not realize that the Isis's Crohn's trial failed in late 1999.
Have a great Spring every one. : )
I belong on all biotech boards when it comes down to a review of the FDA ,s conclusions. Why would you think that I i didn't question the actions or lack there-of Vical's CEO? BTW, the FDA has been known to yield to large pharmaceutical companies under pressure. You have to be a newbie to believe otherwise. I fought MRK from the year 2000 with regard to dangerous side-effects with Vioxx. I was taken off the wantabe IV board prior to being proven correct! I also informed all on this board in 2008 that MIPO would be cleared with many cautions attached . (Black box) While you're waiting for the "lawsuits against Vical" , I suggest you also research the many lawsuits against Isis of which forced Isis stockholders to vacate . I think they might be sorry about now as you may be in the future by not adding a few shares of Vical. Moris, I wish you good health !. (Support the FDA Drug Files to be opened to the public) !
I understood and expected the U.S. FDA to allow Mipo, after extreme pressure from Isis's partners even though 18% of patients on MIPO dropped out due to adverse reactions. There is little information on how the FDAs came to their conclusions, especially, after European FDA failed to support same after the first rejection. The FDA should open its drug files to the public !
Let's hope that there will be continued liver enzyme testing to protect the patients that are burden already by their disease. I'm excited about the future of gene correction which will be the real answer for humanity.
BTW, Vical is on the way back from their A-7 failure... full speed ahead !
Did you real the dark humorous press release today ? "Isis added a substantial amount of cash". Big Stan forgot to instruct his high priced secretary that the cash came from selling his no-revolutionary antisense story... not from producing ONE SAFE Drug in 25 years. Oh well, geniuses love to chirp , "Isis is going to $500 a share." This comes from naïve investors that have no clue as to how antisense works. Hey, it's a great world ! Chuckle with a Chortle. : ) BTW, Isis is up 12% this years while Vical is up 55%. Hmmmm.
Hi jet, thx.
It's humorous to me that a few on this board think I'm 50 different people. I know of three people who use phrases and sentence structure of similar so -called style. Chuckle. I did look into RNN but it had made a move. I did purchase AGEN, I have one more to purchase that's in competition with Vical. BTW, Isis is running on fumes, remember, antisense is not a cure for any disease , unknown to the hype artist on Wall Street. Gene therapy remains the future !!! Big Stan agrees with me . Jet, what percentage of your Isis shares have you sold? Isis could be one heck of a pyramid yet ! Antisense technology works but not good enough... side effects will out in the end. This fact doesn't mean that there won't be some use for antisense. BTW, I have not sold one share of Vical. Hang in there... our government will inflate the dollar in the end.
Jet my friend it's not where we've been it's where we're going. Chuckle. Good health to all ! I'm awaiting antisense validation... maybe some day. : )
Congrats to my friend jetman. I hope that you held on to your stock ? Is the genius finally making a few bucks? He said he bought Isis for one $1.00 . Chuckle or is it a chortle ? : )
May GOD speed !
I took a minute to read your "Breakdown of Vical." I was surprised how little you know with regard to Vical's filing of 13 investigational new drug applications & their holding of four master files for manufacturing recombinant DNA products. Maybe you should partake in adding a few Vical shares to your holdings. Naked-DNA vaccines will not require dangerous antisense painful spikes in the body every week . Vical's infection disease vaccines will be their safe future. BTW, what percentage of your Isis holdings have you sold?
Wish you well while you stay aware of the thin Isis ice .
I still say this group could be on dark American Gree...d. Yes, I'm jealous but not on the way you may think... ya see, I work and produce a product for my meals. Go get em insiders as the geniuses love it ! Chortle. : )
Stock looks strong in the market and wants to go higher. Yes, this could be a tulip area with one of the greatest stories in modern day ! No drug but apparently none is needed in this day & age. Enjoy. Hey Doc Kuz... I'm sorry that you sold your Isis shares. I heard that a load of old timers did also... I mean besides every one of the insiders. Chortle : ) I'm staying strong with Vical
Gosh, where will it end ? You need one scary drug to combat the side effects of other scary drug ! I have to wonder how many treatments humanity will have to suffer why the drug makers keep piling on the profits ? So, the insiders become wealthy while the stockholders chirp, "buy , buy"! Of course I want the research to continue for the good of all, but, not to sell an unsafe drug that gives a patient slow agonizing death. Amen.
2013 & start of 2014 even Richard the actor is kicking them out just in time to have them all replaced for free. What a dark life. Chuckle with a chortle. Big Stan must be beside himself as he never expected this fiasco. Way to go dwarf ! : )
The first offer is $3 , $5, $8.50 final offer $12.50. Then the Herpes earnings come in... $30 +.
Darkouttonnight missing sourdough. : (
Apparently this guru didn't know that the Isis Crohn's trial failed with all of the rest of the antisense drugs trials. I've learned that a great story stock can be hyped to the moon. This reminds me of when I placed my Strong Buy on Isis at $7.16 in March 2012. The only reason I did this was due to the low stock price of Isis in comparison to companies in the biotech area... NOT, due to my expectations of success in the antisense drug field. Antisense dangerous side-effects still prevail to this day. Large molecule, lack of oral , liver problems, once a week spike in the body etc. expose the fact that antisense is a very risky investment at this time despite all the revolutionary hype. This reminds me of Human Genome which went to over $100 a share only in the end to be purchased for $15. at any rate we can hope for the best. Yes, I still like Vical. Smile. : )
A-7 was a disaster for Vical's stock price. What you should remember is that the insiders (Vijay etc.) came over from Merck for Naked-DNA vaccines. This is their area of expertise, to sell now would be a huge mistake IMO. A later purchase will cost an higher price. I've been trading VJET with lucky success and have purchased VEEV at $32. Normally, I don't trade stocks in general but the future of 3-D printers interest me. I'm holding 100% Vical with feelings of security too. Take care & be well !
Jetman, when you mention problems with DNA why did you leave out Vical's Naked safe DNA ? RNA is chemically similar to DNA; indeed, its molecules are made from DNA templates in the nucleus. Over the last five years it has emerged that three types of RNA (MRNA, rRna and trna are not alone. There are also arna, lincrna, mirna, pirna, sirna, srna and many others. Isis and all of their so called partners still, are not clear on what they all do!! What is clear is that 2% of it encodes proteins, and that the other is 98% junk. If scientist could figure out how RNA came into existence, it may explain how living things came to be. Learn that first, then find the answer to the rest. In 1994 Isis and Vical along with HGSI were working together on this science. Today , Vical is an important player in SAFE Naked-DNA vaccines ! It's ok that the funds are naïve about this fact but soon even the naïve may catch on . Yes, antisense has a long, long way to go ! I wish you all well & stay healthy !
CEO & crew are scared the antisense bubble will burst at any minute. Take, take, take from the geniuses. Bosssco, explain to them that there is a higher power. Question for 2014, can the insiders cover up the liver damage plus? This may be the 25th year in a row with no viable safe non-toxic antisense drug. Think about this fact to see the light. Good luck all. : (
Yes, they are backing away, can you blame them ? Sure, Vical will or should out perform Isis in 2014... no brainer. Isis had a good run up on deals, however, I don't see any viable drugs in the near future ? Isis pipelines don't mean one iota if you consider the Isis history of the last 24 years. 2014 will bring the usual promising clinical trial progress with no substance in reality! Again, the CEO can sell fools gold and has by the ton. I have to give him a pat on the back and hope he will pass a portion of his easy millions onto real gene therapy drug research ! Good health to all ! : )