I doubled down as well at $3.41. Let's do this. My average is $4.12
Sant Chawla M.D. Director of the Sarcoma Oncology Center and Principal Investigator of the Phase III pivotol trial is very excited about it's ENORMOUS potential. Ever see the movie Armageddon? It's like a space ship landing on an asteroid (tumor) carrying a nuclear war head to blow it to hell.
The Overall Survival(OS) data from the Phase IIb first-line trail will be shared sometime in the second half of 2014. Well, that means you better be in this stock starting July 1st. It can come out any day from Tuesday until the end of December.
"We are hopeful that the next stage of development for aldoxorubicin, a well-tolerated single agent that lacks the cardiotoxicity associated with doxorubicin therapy, will demonstrate its potential to meaningfully extend survival, and will lead to a new treatment option for patients fighting this aggressive, life-threatening cancer."
A total of 123 patients with advanced soft tissue sarcomas were enrolled in the 31-centre Phase IIb trial and they were randomised 2:1 to receive either 350mg/m2 of aldoxorubicin or 75mg/m2 of doxorubicin every three weeks for up to six cycles.
These patients were then followed every six weeks with CT scans to monitor tumour size.
Two approaches were used to evaluate the efficacy of aldoxorubicin compared with doxorubicin in these patients, which include evaluation by the study investigators, as well as assessment by a blinded central laboratory review.
The trial's primary endpoint was PFS and secondary endpoints included PFS at six months for each group, ORR and overall survival, which will be reported when the clinical trial is complete.
CytRx president and chief executive officer Steven Kriegsman said these results were selected for presentation at the 2014 American Society for Clinical Oncology (ASCO) Annual Meeting.
"We look forward to discussing the data with the oncology community and to reporting the full overall survival results from this trial in the second half of 2014," Kriegsman said.
"In parallel, we continue to actively enroll patients in our pivotal global Phase III trial in second-line STS. In that Phase III clinical trial, we are permitted to dose until progression, which could substantially enhance the benefit for sarcoma patients."
Citi credit analyst James Finnerty initiated coverage on KB Home (NYSE: KBH) 4.75% 2019s with a Buy rating.
Finnerty said, "We believe KBH has upwards ratings momentum in the medium term given company guidance for improved profitability in 2014 which is expected to lead to the reversal of a large percentage of their Deferred Tax Allowance (DTA). We believe the resulting benefit to balance sheet leverage could be a potential positive rating catalyst."
He added, "KBH management is guiding for full year of profitability in 2014 which they expect will allow them to reverse a significant portion of their DTA of $844mm. The reversal would boost shareholders equity and therefore reduce debt/cap. At recent investor day guided to Net Debt/Cap ratio target of 40-50% by 2016 vs. 77% as of 1Q14 (57% adjusted for DTA reversal). At the time they also noted that ratings agencies were waiting for the reversal before incorporating the lower leverage into KBH’s ratings.
Homebuilding is picking up in Southern California after several slow years. Building permits were up 44% in the Los Angeles metro area in 2013, and have continued to climb this spring
The website still displays Come visit DigitalGlobe at GEOINT 2013! Please give us something current and we're not understanding the downhill decline in the share price.
KB Home is building off of the continued demand for housing in New Braunfels with a new community called West Village at Creekside.
Located along FM 1101, just east of Interstate Highway-35, West Village will join two existing neighborhoods the builder already has in this city just northeast of San Antonio — Caprock, located off of SH 46 and IH-35; and Legend Point, off of West Klein Road.
And it’s very possible that there will be more communities to come, according to Brett Dietz, who is the president of KB Home’s San Antonio division.
“We are aggressively searching for land in the San Antonio and New Braunfels area,” he says.
It’s not hard to understand why KB Home is targeting these two cities.
The San Antonio MSA, in general, has shown consistent improvement for several years now, explains Dietz, who points out that between year-end 2012 and year-end 2013, the number of new-home starts (number of homes builders commenced work on) was up 9 percent.
Over the same period of time, in New Braunfels specifically, new-home starts rose around 42 percent.
“ New Braunfels is the fastest growing submarket in the entire San Antonio MSA,” Dietz says.
And within this bustling community, much of the growth has been centered around the land that will soon be home to KB’s newest subdivision.
KB purchased the 120 acres for West Village about a month ago. The land is located right off of IH-35, Dietz says.
The community itself will feature amenities like a private swimming pool, walking trails and a children’s playscape. West Village will also be in proximity to three Comal Independent School District schools — an elementary, a middle and a high school.
The neighborhood will also benefit from its proximity to two wellness centers. Then there is the nearby retail mecca that is The Village at Creekside— which has proven to be a great consumer draw and a prime source of employment for many residents.
“We’ll have fantastic schools, great access and jobs — it’s a trifect
Can iron ore prices change quick or is it always a gradual move? Wondering what this can look like in a months time.
How can an investor benefit?
Activist shareholders are some of the smartest investors around, and their involvement with a company is a strong signal of their belief that the stock is undervalued. While the monetary value of their stake in a company is proof that they are putting their money where their mouth is, their willingness to engage in a proxy fight is a concrete indication of the courage of their convictions, i.e. they are willing to go the distance to drive positive change.
Although the participation of activist shareholders cannot and should not be the only yardstick for measuring the attractiveness of an investment, it is a definite plus point. Apart from pressuring management to take measures to improve efficiency and drive value, activist shareholders can also urge the company to follow sound corporate governance policies.
While a proxy fight that is resolved quickly may benefit shareholders, a nasty and long-run proxy battle is in no one’s best interests, as it distracts management and may lead to less than optimal operating performance for the company.
Investors can stay tuned to the investments made by activist shareholders with the best long-term record by scouring their regulatory filings. These include the Schedule 13D in the U.S. – which must be filed with the SEC within 10 days by anyone who acquires more than 5% of any class of securities of a publicly traded company – and the “early warning” report in Canada, which has to be filed if an entity acquires more than 10% of any class of equity or voting securities of a company.
Buy a little here and hold it. For those of you that understand options. Buy a few contracts.
I like the April 19th $17 calls for $2.45 per share. Let's get this back up to $19.45. Come on let's do this, send the word!
The 2014 outlook for domestic iron ore producers is bright, with demand strong and prices steady or increasing, but domestic metallurgical coal producers are struggling with low prices, environmental issues and regulatory constraints.
Cliffs Natural Resources Inc., an iron ore supplier to much of the North American steel industry, expected a strong finish to 2013 and anticipates continued strength in 2014. The company reported third-quarter sales of 6.3 million tons from its U.S. operations, down slightly from 6.6 million tons in the same period a year earlier. The Cleveland-based company, which mines iron ore in Minnesota and Michigan for the domestic steel industry, expects to post U.S. iron ore sales of 22 million to 23 million tons in 2014, in line with the company’s annual average for the past five years. Cliffs pointed out that a “significant portion of U.S. iron ore volume is contracted for the next decade.” The company also expects to book sales of nearly 6 million tons from its eastern Canadian iron ore operations. Besides supplying North American steel customers with domestic iron ore, Cliffs also exported 1.8 million tons in the first three quarters of 2013, about half of it destined for customers in Europe.
Peter Kakela, a professor of resource development at Michigan State University in East Lansing and the nation’s foremost authority on domestic iron ore production, is optimistic about the industry going forward. Last year was “a pretty solid year for iron ore demand in North America ... and I don’t see any reason to ratchet those expectations down for 2014. And I certainly don’t see prices going down,” he said.
Kakela based his predictions on a North American economy that seems to be picking up steam and pent-up demand that is fueling light vehicle sales. “I know I’m wearing rose-colored glasses,” he said, “but the outlook does seem pretty good.”