It's entertainment. Institutions move stocks, not Adam F. Don't sweat it. The truth wins in the long run every time.
1. Not a terribly scathing article which says something coming from Adam F
2. He has friends at many hedge funds
3. He is just doing his thing.
Trust the doctors not the reporters on this one.
Note just out. They think will be recommended on Tuesday. So that makes 4 out of 4 sell siders so far.
You realize that you are quoting the sponsor's document, right?
By the way just checked with my child psych colleague and he said they try to avoid using two antipsychotics in children even more than adults. So even though it may happen, how we were trained in residency (and his child fellowship) was that combinations of antipsychotics are reserved for the most severe patients.
It does happen all the time but it's best to avoid if possible in my opinion and leads to all sorts of side effects. But yes you are balancing risks and benefits.
Certainly not in the elderly which was what my comment was based on. Also I'm not a child psychiatrist so fair enough. I would still say that prescribing more than one antipsychotic should be an option of last resort and after all behavioral approaches have been exhausted in my opinion.
Just because it is happening does not mean it SHOULD be happening.
That 50% is crazy benchmark to judge success or failure on. And no one taking care of psychotic patients came up with that number. If they did, then they need to go back to residency and start over...
Parkinson's is a neuro degenerative disorder so worsens over time. If you aren't modulating dopamine that the medication should not directly worsen PD
Because FDA has a duty to make sure medications are effective and safe. We all want them to be very critical of the data. That said I think a 30-50% reduction in saps-PD is clinically relevant. Heck I think 15% would be clinically relevant. The medications we have now are not that effective and have significant side effects. This is an unmet medical need. I really hope the FDA approves this medications. Neurologists and psychiatrists need new mechanisms for psychosis other than dopamine modulators.
Technically delusions are fixed false beliefs and halluncations are hearing voices or seeing things
And they are getting regular check ins with doctors which in and of itself can be stabilizing for a patient