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Curis, Inc. Message Board

donallenthompson 10 posts  |  Last Activity: Jan 10, 2015 9:17 AM Member since: Aug 13, 2009
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  • Reply to

    Loko's New Gel Patent

    by donieboyie7 Jan 9, 2015 1:39 PM donallenthompson Jan 10, 2015 9:17 AM Flag

    & now you know my alias as well.

  • Reply to

    Loko's New Gel Patent

    by donieboyie7 Jan 9, 2015 1:39 PM donallenthompson Jan 10, 2015 9:14 AM Flag

    I can see that the new patent is a comment on our management. Have they found something of value for the company? Or will the new patent be a distraction for them & maybe a waste of $s. I thank Loko for telling us about it so we can decide for ourselves. Had he not shared this information, we may have never known about it. My wild & crazy guess was just that, nothing else. However, I think it is a logical & possible conclusion if depression is CNS related, & I think it is. Got the clarification I want. I do think the Testosterone asset is of great value. I read here for the diversity of ideas. I appreciate all of your input. I will stay with ATRS or go some where else with my investment depending on my own analysis. Thanks!

  • Reply to

    Ethanol in the injector

    by nammuang Oct 11, 2014 11:46 PM donallenthompson Oct 12, 2014 4:29 PM Flag

    Seeking the same information here that you are, but I don't have the chemistry or pharmaceutical background that is perhaps necessary to fully understand the issue. I have to believe that there is a very good reason for this patent. I don't believe they would have wasted the time or resources to pay to have somebody do the research on this & then, file for a world-wide patent otherwise. The only answer I have been able to come up with in this delivery approach (using ethanol, the utility of the method, & perhaps less bad side effects) is that management believes it will in some way limit or restrict any possible competition for some of their future products such as their testosterone SC shot. I believe LD has suggested this in his comments at Seeking Alpha. I like the fact that LD is a good researcher/detective & is willing to go out on a limb & make predictions. Since none of us seem to be insiders here, this is what we all have to do at times if we keep investing in these type businesses, & sometimes we could be wrong. I don't post much, but I read here everyday, & I am invested in ATRS. I still see some hope here.

  • Reply to


    by lokodaug Oct 10, 2014 9:15 AM donallenthompson Oct 10, 2014 11:07 AM Flag

    He refers to himself as lokodude or something like that there, I believe. It is also a very interesting turn of events!

  • Reply to


    by lokodaug Oct 10, 2014 9:15 AM donallenthompson Oct 10, 2014 11:03 AM Flag

    Lokodaug has provided additional clarification on this new patent at the end of Ali Yasar's last report on ATRS Testosterone injection plus the patent reference. What I saw looks significant to me, but I am not really qualified to evaluate the patent. Hope some of you will check this out & report back here your ideas.

  • donallenthompson Sep 18, 2014 12:01 PM Flag

    I thought INO/ONCS agreements precluded this. I believe ONCS has exclusive right to inject/electroporate into tumors. When I held ONCS shares, I read or heard this in a presentation done by ONCS. No longer have ONCS shares. I now hold only INO because I think it is the better investment long term.

  • Reply to

    Nasal testosterone approved

    by whogo70 May 29, 2014 8:31 AM donallenthompson May 29, 2014 10:30 AM Flag

    I guess sneezing & coughing would have to be out of the question for any user. Couldn't use in cold, flu, or allergy season.

  • donallenthompson May 14, 2014 10:57 AM Flag

    Questions for you: How will LPCN market this product? Since they have an improved, one a day pill 18 months more or less behind & backing up the two a day pill would any BP or other smaller company want to partner the lead drug with the other so close behind? The 2 a day pill would be quite expensive to manufacture, promote, & distribute, & sell if the 1 a day is right behind it. Does any delay in marketing the oral T pill (because of the 1 a day pill in waiting) give the advantage to ATRS? I guess only a side-by-side comparison of the two stage 3 trials after completion will show if one or the other company has any other advantage over than dosing frequency. We know the ATRS shot will be a once a week, near painless injection. I think that's all we seem to know for sure. As of now, don't think either company has experienced much if any negatives in prior studies. Eventual cost of the product will be a factor. Market will probably be big enough for both. Time will tell.

  • donallenthompson Mar 3, 2014 8:26 PM Flag

    During the last year, I remember Dr. Kim saying (at some event he spoke at) that the latest HPV results wouldn't be 100%, but that they would be good. I wondered at the time how he could be so sure. Somewhere, somehow Inovio staff has seen evidence of the disappearance or reduction in size of PC lesions at least enough to give them confidence of success in the Phase II trial. They might have seen signs of lesion disappearance, as you suggest, in the Phase I trial. Good observation.

  • donallenthompson Feb 26, 2014 12:57 PM Flag

    All things in biotech (as well as in life) can fail. I have lost lots in these type stocks, (so I have been wrong before), but I believe electroporation along with DNA vaccines will work. Look at all the studies thus far. Great results for antibodies & highest T cell responses ever. It is well known how electroporation works technically. Inovio insiders are of highest quality in experience & science. Many are stock holders with large holdings. I know the HPV study, we are waiting results, on is double blinded & placebo controlled, but still they have to be seeing some positive things happening that have never been seen before like the disappearance or reduction in size of lesions. Staff appears to be very positive about the results & are planning on their Phase 3 now. I assume Inovio staff has access to this type of information (correct me if I am wrong). We know what Roche thinks. Dr. Kim has said that what he endured during their examination of the company was like having a colonoscopy. Many of us are familiar with that experience! So I remain positive. Much of my stock was purchased at way under a $. There could always be set backs in this or anything, but I don't expect it. I look at the potential of check point inhibitors combined with our technology as insurance that we will have success in the cancer field.I am diversified in other things, not just in INO. You should be as well.

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