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donker3 236 posts  |  Last Activity: Jul 5, 2015 8:10 AM Member since: Dec 17, 2009
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  • Reply to

    Contgradulations, Donk !!!!!

    by hollisddd Jul 4, 2015 9:38 PM
    donker3 donker3 Jul 5, 2015 8:10 AM Flag

    Hollis,

    You were far more interesting when you were telling your "love stories"...

    If your so smart, why didn't you post the patent info first, instead of riding on someone else's coat tails???

    DONK

    Sentiment: Buy

  • The NOTICE OF APPROVAL was issued just a couple of days afterwards....!!!

    Check for yourselves....

    Go to uspto pair and enter:

    13/258,687

    CLICK ON TAB top of page:

    Transaction history

    AND YOU'LL FIND THIS INFO:

    02-21-2014 Mail Notice of Allowance
    02-18-2014 Document Verification
    02-18-2014 Notice of Allowance Data Verification Completed
    02-13-2014 Examiner's Amendment Communication

    THIS PATENT would be the HOLY GRAIL of TB4 and NEURO:

    NOTE CLAIM #1:

    ""A method of treating neural injury by myelinating damaged neurons, which comprises administering to a subject in need thereof a pharmaceutically effective amount of thymosin B4, so as to myelinate said damaged neurons.""

    GO TO GOOGLE PATENTS AND READ DESCRIPTION OF THE APPLICATION:

    US20120021992 A1

    ABSTRACT
    Thymosin β4 can be used to treat neuronal and brain injuries that are accompanied by neuronal cell death or injury, including injuries caused by stroke or trauma and injuries caused by neurological and neurodegenerative disease. In particular, stroke and multiple sclerosis are examples of conditions which may be ameliorated by treatment with thymosin β4. Thymosin β4 has been found to restore neurological tissue through several effects on several neurological parameters which are improved by administration of thymosin β4 to a subject in need of neurological tissue restoration. For example, thymosin β4 improves axonal myelination, migration of neural progenitor cells, neural progenitor cell proliferation, differentiation of neural progenitor cells into mature neurons, differentiation of neural progenitor cells into mature glia, nerve regeneration, and brain remodeling at locations of brain injury.

    HUGE RESEARCH MONEY IN "traumatic brain injury"----especially in MILITARY.....!!!!!

    AND REGENERX HAS """:THE RIGHTS"""" TO THIS PATENT....

    It would be a HUGE ASSET for REGENERX....

    WATCH PATENT APPLICATION PROCESS and buy before the CROWD.....!!

    THE DONKER

    Sentiment: Buy

  • donker3 donker3 Jul 2, 2015 11:16 AM Flag

    Teach,

    Will do....

    Thanks!

    THE DONK

  • donker3 donker3 Jul 2, 2015 9:44 AM Flag

    Teach,

    Thanks for your articles....

    "The Rails" are getting greased in the background while official "Regenerx News" has been silent....

    Heart info and neuro are being campaigned in the PUBS....

    That's a TELL ......

    THE DONKER

    Sentiment: Buy

  • per USPTO PAIR #13/258,687:

    Date Transaction Description
    07-01-2015 Examiner's Amendment Communication

    I DON'T THINK IT WAS POSTED UNTIL LATE IN THE DAY OR THIS MORNING....

    When you see "Examiner's Amendment Communication",,,,,
    many times they're hammering out or tweeking the patent application so it'll meet Examiners Guidelines to pass a NOTICE OF APPROVAL.....

    BUT INSIDERS (RGRX, Henry Ford,Sigma, Lees, Koreans, and all their close friends) would be privy as REGENERX has claimed they're paying the patent atty and ARE USING SAME PATENT ATTY GROUP that REGENERX USES......

    Maybe that's why we see the trading activity yesterday....

    THIS PATENT APPLICATION is the ESSENCE of MIKE CHOPPS work on TB4/NEURO at HENRY FORD....

    This patent application was given a NOA last year but was later shot down for a "technical foul" which may have now been overcome with the "amendment"....

    VERY IMPORTANT PATENT FOR REGENERX AS THEY OWN THE RIGHTS

    Tuesday, April 8, 2014
    Michael Chopp wins the Abraham White Scientific Achievement Award
    Distinguished Professor Michael Chopp, of the Department of Physics, has won the prestigious 2014 Abraham White Scientific Achievement Award. Chopp, who performed this research in his laboratory at Henry Ford Hospital, received the honor for his discovery of the role of thymosin beta4 in the treatment of brain injuries and neurodegenerative diseases.

    AFTER THAT ANNOUNCEMENT, THE patent application got shot down at USPTO....

    Go into USPTO AND READ HISTORY---VERY INTERESTING.

    02-21-2014 NOA Notice of Allowance and Fees Due (PTOL-85)

    THEN DISASTER STRUCK!!!!!

    06-09-2014 CTNF Non-Final Rejection

    HELLUVA AN UPSET FOR REGENERX AND PARTY POOPER AT "KNIGHTS OF THYMOSIN" 2014 MEETING IN ITALY LAST YEAR......

    READ UP ON:
    Michael Chopp and THYMOSIN BETA 4

    GOOD NEWS IN THE MAKING IT WOULD SEEM........

    BUT WHO KNOWS,,,,,,????

    THE DONKER

    Sentiment: Buy

  • at uspto pair.....

    And no fee has been paid to further the "dry eye" patent 13/219,394 in next step of appeal process it seems...

    THE DONK

    Sentiment: Hold

  • donker3 donker3 Jun 26, 2015 3:15 PM Flag

    Teach,

    I see what your saying.....

    It will be interesting to see how the USPTO examiner rules on this.

    DONK

    Sentiment: Hold

  • donker3 donker3 Jun 26, 2015 1:26 PM Flag

    Teach,

    Get into uspto pair and read up on this a bit.....

    See what they, REGENERX, are attempting to do here.

    If they get a patent on this particular application, might bode well for dry eye.

    Might be a different tactic for them to get some patent coverage.

    DONK

    Sentiment: Hold

  • AND CAN BE FOUND in USPTO PAIR UNDER:

    Application number 13/876,767

    MIGHT WANT TO READ UP ON IT'S PROGRESS, ARGUMENTS, AND SEE WHAT THE EXAMINER DECIDES before you "shoot from the hip" about such things as ""precedence""... or PRESIDENTS AS YOU SAY.... CHUCKLE

    That's why they have USPTO EXAMINERS..... LOL

    And if REGENERX and their PATENT ATTY'S have decided it's a good strategy,,,,,

    We should wait and see what the EXAMINER SAYS....

    REGENERX,,,,, LIKE ALL BIO's ,,,, needs/desires patent protection to make the BIG MONEY and have extended rights to IP....

    Might well be a "backhanded way" of getting patent coverage for their drug.

    But who knows,,,,

    THE DONK

    Sentiment: Hold

  • donker3 donker3 Jun 26, 2015 12:00 PM Flag

    They other thing of IMPORTANCE ON THIS PARTICULAR PATENT APPLICATION:

    NOTE THE PRIORITY DATE!!!!!!

    Publication number US20130203684 A1
    Publication type Application
    Application number US 13/876,767
    PCT number PCT/US2011/053907
    Publication date 8 Aug 2013
    Filing date 29 Sep 2011
    ***************Priority date 30 Sep 2010*************

    THIS IS A FAIRLY RECENT DATE in the world of patents and they, REGENERX, would have a LOT OF PATENT COVERAGE TIME.....

    So in summary, if REGENERX can't get a SPECIFIC PATENT for TB4 INDICATION OF DRY EYE,,,,
    neither can anyone else.....

    But they might have PATENT COVERAGE for TB4 DOSING of LIVE HUMAN PATENT....

    Might well be NOVEL way to APPROACH THIS SITUATION of patent protection.....

    DONK

    Sentiment: Hold

  • donker3 donker3 Jun 26, 2015 11:29 AM Flag

    It's an interesting concept because if you could PATENT A SPECIFIC thymosin beta 4 delivery system and get that specifically approved for your NDA with the help of ORA,,,,,,

    Who knows, they might have something there or that could be their underlying strategy FOR HAVING PATENT PROTECTION....

    DONK

    Sentiment: Hold

  • Reference:

    Method of achieving a thymosin beta 4 concentration in a human patient
    US 20130203684 A1

    KEEP IN MIND THIS ONE'S ON AN EXAMINERS DESK NOW FOR OVER 60 DAYS....

    """THE INTERESTING THING""" IN THIS APPLICATION, THEY ARE APPLYING FOR A PATENT under the CLAIMS portion only for A PATENTED FORMULA to deliver TB4 to a LIVE HUMAN and there is no INDICATIONS/DISEASES named what soever of what they plan to treat UNDER THE CLAIMS COLUMN which normally would contain or SPECIFY what they plan to treat....

    So really they want to Patent a TB4 DELIVERY SYSTEM and in the left column they list under DESCRIPTION:

    *****1. Technical Field*****

    The invention relates to the field of medicinal treatment and in particular to methods for providing a pharmaceutical dosage of thymosin beta 4 to a patient.

    AND UNDER the heading....

    *****DETAILED DESCRIPTION OF EMBODIMENTS OF THE INVENTION:*****

    5 PARAGRAPH you'll notice they include:

    The term “body portion” includes any tissue of the body, for example but not limited to: breast tissue, cardiovascular tissue, central nervous system tissue, colon tissue, connective tissue, endometrial tissue, gastrointestinal tissue, heart tissue, heart valve tissue, liver tissue, muscle tissue, nasal cavity, pancreatic tissue, placental tissue, rectal tissue, renal tissue, skin tissue, urogenital tissue; and any fluid or secretion of the body, for example but not limited to: amniotic fluid,**** aqueous humor of the eye*****, blister fluid, blood, cerebrospinal fluid, lacrimal secretions, plasma, saliva, serum, synovial fluid, tear fluid, urine, vaginal secretions, *****vitreous humor of the eye*******, and wound fluid; and includes the total or entire body, for example for systemic administration to the whole body.

    ASTERISKS ARE MINE....

    I'm pretty sure that in DRY EYE you'd administer TB4 to the AQUEOUS HUMOR....

    So maybe they are attempting to get a DRY EYE PATENT thru the back door so to speak....

    DONK

    Sentiment: Hold

  • donker3 donker3 Jun 24, 2015 10:44 AM Flag

    Teach,

    If you search the Chinese SIPO patent site, you'll see what happened to REGENERX'S china dry eye patent in 2012...... Expired for failure of Regenerx to pay patent fee's....

    Also, look at all the Chinese Company's getting tb4 patents and many "over" patenting Goldsteins work....

    With that in mind, you can see why JJ didn't pay the patent dues and allowed patent to expire...

    Then you take into consideration the PHILOSOPHY OF CHINA'S PATENT OFFICE giving total home field advantage to Chinese Company's and their expectations of now exporting their own IP derived products,,,,,

    China's already sold more TB4 than Regenerx and will continue to do so with their own patented process for HIGH GRADE AND INEXPENSIVE TB4 which came out of a military university it would seem.

    It doesn't bode well for Regenerx in that neck of the world.....

    Don't hold your breath on that one....

    DONK

    Sentiment: Hold

  • donker3 donker3 Jun 24, 2015 9:05 AM Flag

    Teach,

    If your going to just "wing it", at least get your facts lined up.....

    When did Lee's give Regenerx a million dollars???? lol

    When your STARE at China for Regenerx's "financial redemption",,,,,,

    more than likely you'll see your NOSE FALL OFF before your see any large amount of DRY EYE money leave CHINA for Regenerx...

    Why perpetuate a "FALSE MYTH"....???

    What's the purpose???

    The BS-ed just becomes the BS-er....

    DONK

    Sentiment: Hold

  • donker3 donker3 Jun 23, 2015 11:01 PM Flag

    Teach,

    The question should/would be:

    Was the trading here, including the Koreans, ever totally on "dry eye"?????

    REGENERX has no US DRY EYE patent and actual "dry eye specific patent application" is hopelessly bogged down in the patent appeal process which takes on average 26 months from the date the docket number is assigned (Regenerx doesn't even have a docket # assigned and it doesn't seem they have sent the additional funds to USPTO YET).....LOL

    AND in CHINA,,,, FINKELSTEIN let the seemingly only actual DRY EYE PATENT they had expire due to non payment of yearly dues..... Which should tell you that after all the thousands upon thousands of dollars that Regenerx pays for PATENT ATTY'S in order to get an actual DRY EYE PATENT and then in 2012 let it expire for NON PAYMENT of MEAGER MAINTENANCE FEE'S they didn't think the patent was WORTH THE PAPER IT WAS WRITTEN ON...... LOL

    The SMART MONEY here is trading on news behind the scenes on THE HEART.....

    THEY ACTUALLY HAVE PATENTS in hand....
    numerous ones including the latest one assigned to GOLDSTEIN which is about heart and related to SMART/RILEY RESEARCH IN ENGLAND....

    Not to mention,,, as announced previously by REGENERX a MATERIAL TRANSFER AGREEMENT with the UNIVERSITY OF MARYLAND giving them the "IP RIGHTS" to the FIBRIN TECHNOLOGY:::::

    Compositions and methods utilizing fibrin beta chain fragments
    US 8722623 B2

    which was patented last year but still not officially even acknowledged by UNIVERSITY OF MARYLAND (and they're damn proud of their patent portfolio----check their PATENT BRAG SHEET) most likely because of a CONFIDENTIALITY AGREEMENT that is involved in the MTA.....

    Leonid Medved's research on ISCHEMIA AND REPERFUSION which now includes a PATENT has been going on since 1998 which HUGE BACKING OF NIH and others and they, the university of maryland, hasn't even announced the patent or said boo on the research which is the HOLY GRAIL of heart.

    DO A SEARCH ON:

    Ischemia and reperfusion

    DONK

    Sentiment: Hold

  • ************# 13/876,767
    METHOD OF ACHIEVING A THYMOSIN BETA 4 CONCENTRATION IN A HUMAN PATIENT

    THIS ONE HAS BEEN SITTING ON EXAMINERS DESK EXACTLY 2 MONTHS....
    So it should be close to being looked at.

    This patent application is IMPORTANT IN THAT IT COVERS MANY APPLICATIONS including heart.
    Find it in google patents under:

    US20130203684 A1

    READ THE ABOVE APPLICATION AND ON THE LEFT SIDE UNDER:

    Healing and repair in:

    Breast tissue
    Cardiovascular tissue
    Central nervous system tissue
    Connective tissue
    bone
    cartilage
    joints
    Epithelium
    Eye
    cornea
    retina
    Gastrointestinal tissue
    Liver
    Mucosa
    Muscle
    Neural tissue

    ***************The next one to pay close attention to is:

    ************#13/258,687
    METHODS FOR IMPROVING NEUROLOGICAL OUTCOME AFTER NEURAL INJURY AND NEURODEGENERATIVE DISEASE

    This patent application is CHOPPS/HENRY FORD

    VERY IMPORTANT AS REGENERX HAS SAID THEY own the rights to it and have been paying the atty fees.

    Note that PATENT ATTY has attached a statement from HENRY FORD which is showing date priority over the BEVEC reference which was used as an OBJECTION OF PRIOR ART by BEVEC....

    BOTH OF THESE APPLICATIONS might very well STITCH Regenerx's patent portfolio together to add VALUE HERE.

    THE DONK

    Sentiment: Hold

  • Reply to

    The WILD CARD on RGN-259 would be.....

    by donker3 Jun 18, 2015 10:54 AM
    donker3 donker3 Jun 18, 2015 2:36 PM Flag

    Would the Army pay JOINT VENTURE or Regenerx.....

    Don't necessarily need patent rights for Defense Contracts it seems....

    Interesting concept which would give some IMMEDIATE VALUE to RGN-259...

    Helluva lot of research done on that by Sosne and Wayne State in collaboration with US Army...

    Wonder who'd rake the in the GATORS------Regenerx or JV?????

    DONK

    Sentiment: Hold

  • donker3 donker3 Jun 18, 2015 1:54 PM Flag

    Doc,

    As to your:

    " Got into this because of a trusted colleague that got over 1 million shares here in early 2000."

    Maybe label him/her as "good friend" vs "trusted colleague" unless his basis is really, really low....LOL

    Your seemingly penalized for too much foresight in Biotech....

    My hero would be someone who bought in Nov and Dec of 2013...

    This isn't a lottery ticket at this point, REGENERX has the GOODS NOW, just depends on how they PLAY THEM....

    DONK

    Sentiment: Hold

  • donker3 donker3 Jun 18, 2015 12:30 PM Flag

    Doc,

    As to your:

    I hope they find a partner for 352

    WHO'S TO SAY THEY DON'T HAVE ONE IN THE WINGS WAITING......

    Maybe that's what the Koreans are trading on and structuring companies...

    SMART MONEY never bets heavy on what they MIGHT GET......
    Only RETAIL DREAMERS....LOL

    But who knows,

    DONK

    Sentiment: Hold

  • donker3 donker3 Jun 18, 2015 12:12 PM Flag

    Hey Trotty,,,,

    Nice to see you back....

    I'm listening to SOME CLASSIC myself:

    Willy Nelson's "on the road again"...

    Not quite as 'high brow' but "it'll get 'er done"....lol

    DONK

    Sentiment: Hold

RGRX
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