mikesmilitaria, I have tried to get doctor.stockpicker's attention on the problems of his prescribing Metformin, but I have never gotten any replies from him. I share your concerns about Metformin, but doctors appear to prescribe it all the time to Type 2 diabetics. That practice should stop I hope with Afrezza's availability. I lifted your Metformin post below. Maybe you can get doctor stockpicker's attention.
"That one pill per day, like Metformin is poison.
The RX of which you speak forces the body to "circumvent excess sugar" and pass it thru the kindeys and out via urination. Now if sugar(diabetes) destroys your organs and now with that one pill a day, you put the kidneys thru handling excess sugar, day in, day out, what ultimate effect will that process have on your kidneys? That is one of the box warnings on the one pill per day.
Afrezza is natural human MONOMERIC insulin that has a therapy profile identical to that of the pancreus.
It has NO adverse side effects and "balances the body's sugar" the way nature intended.
Metformin takes the pancreus and forces/squezzes the organ to produce insulin so you in fact, take a weak, barely functioning organ and wear it out, pushing you to T1 diabetes from T2."
evlradr, brheavy posted such a study MNKD did some years ago in which they actually did part of the small trial study by inhaling Afrezza without eating anything before or after inhaling, and those patients did not experience hypoglycemia. I believe it was in one of those PubMed abstracts he posts from time to time. I read it within the past 30 days or less.
dmorgan2151, Indian oil company reported to have CHK as its target. Mentions Obama visit to India on January 25 to meet with Modi. FYI.
winwina88, Sanofi will drop the news on you like the Swiss Central Bank dropped the Swiss Franc news today.
centralcoastinvestor, Al let us know the $50 million milestone was to meet the Afrezza volume availability for product launch by January 23. He said MNKD met the milestone two weeks early. Al also said the yields of Afrezza were better than forecast.
Matt Pfeffer, a bone head, is a total goof at presenting, and Hakan Edstrom is a partial goof when he presents. Al Mann needs to be the only presenter at the conference for MNKD, because he can do the job and do it well. If Al is not doing the presenting, then MNKD should cancel.
I noticed uncharacteristic posts, and then I noticed redhaw_20000 (redhaw twenty thousand) is trying to impersonate redhaw_2000.
meifud, many, many analysts said tablet computers (tablets) would not sell. Especially after several examples in the market showed them. Then the market got a tablet that did what it wanted, and the analysts had to return to their sales forecasts and move them up a lot. They forgot the maxim that they mention all the time. That is past performance does not guarantee future results. You may be called upon to adjust your analyst horizons soon too, but you can cite the analysts for any misfortune.
funkyfreshfee, you may not be paying 22% to be short MNKD, but you are paying a stiff interest rate to your broker. Even if you shorted at $9+, your borrowing charge to remain short has risen a lot in the past few months. I see FIDO is charging 18.75% per annum, which is up about 2% more in the past 30 days. Oh and that is a yearly rate, but your broker is raking your account every month.
afrezzauser, I read the honeymoon article you referenced on twitter, the joslin dot org article, and I don't quite understand what doctors or patients are thinking about this period of time after a type 1 diabetic is diagnosed. The article indicates that for some period of time after diagnosis the diabetes appears to get a lot better. I am not sure how that could happen. What made you think your situation was going to be all right after your diagnosis? Anyway it is clear the doctors need to prescribe insulin upon diagnosis, and now there is a real human insulin in Afrezza that patients can have that will, during meal times, keep their blood glucose in normal range (between the lines).
afrezzauser, so were you diagnosed as type 2, then did not take any medication, and then became a type 1? If not what was the progression?
afrezzauser, my comments are to make the same suggestion to you that I made to a poster, doctor.stockpicker, who posted he is a doctor in Oklahoma who takes care of a lot of diabetics. I have never gotten a response from this doctor. My suggestion (and I do not think it is unique) is for type 2 diabetics who are not on any diabetes drug, or are on metformin to begin on Afrezza alone at meal times to dampen the blood glucose excursions and possibly (likely) bring the a1c into an acceptable lower range over time. Yes, I mean discontinue the metformin, which is primarily acting on the liver to reduce the steady state level of glucose. The Afrezza, acting as real insulin, will chemically message the liver to reduce the glucose output during meal time digestion periods.
At least start on this procedure to verify blood glucose level improvements before putting type 2 diabetics on a harsh side effect drug like metformin to bring down glucose output from the liver, or even an injected insulin analog like lantus. I am hopeful that a lot of these research labs and research hospitals will run some of these type of trials with Afrezza and report their results at the many diabetes conventions.
afrezzauser, I have some comments on this to add to your inputs, but I don't have time for a full reply right now. I will give you a complete reply in the next day or two to this particular thread you have started.
afrezzauser, I posted this last night, but it did not appear. During the trials did you always inhale the Afrezza just as you started your meal, or did you sometimes inhale some minutes after your meal started? I was listening to Al Mann some weeks ago either in a video or conference call say he thinks a better time to inhale Afrezza is a few minutes after a meal has started. I think he said up to 15 minutes after a meal has started is all right.
afrezzauser, during the trials did you always inhale the Afrezza just as you started your meal, or did you sometimes inhale some minutes after your meal started? I was listening to Al Mann some weeks ago either in a video or conference call say he thinks a better time to inhale is a few minutes after a meal has started. I think he said up to 15 minutes after a meal has started is all right.
It is in Maryland, and I would like to know if anyone on this board was there or communicated with someone who heard him speak. Besides Al Mann I know Afrezza will be discussed on some of the panels, because Dr. Klonoff, a leader on some of the panels, has written favorable information on Afrezza in the November issue of the Journal of Diabetes Science and Technology that is on the web.