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ImmunoGen, Inc. Message Board

dr.vinmantoo 75 posts  |  Last Activity: Apr 28, 2016 11:21 AM Member since: May 18, 2010
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  • dr.vinmantoo dr.vinmantoo Mar 14, 2016 6:37 PM Flag

    Some PPHM longs have taken to repeating the line that the Docetaxel arm in Sunrise trial showed the best MOS in the history of clinical trials in NSCLC. Presumably they do this so they can keep their laughable sabotage claims going. My sin was to chastise those posting that comment and challenge them either to provide a link to that data, or stop repeating that claim as if it were a fact. That was my sin and why my post just had to be deleted ASAP. It really is sad.

    By the way, Chris (md1225) was given the cold hard truth on the BioValues board by DewDiligence. Do you suppose he will go to IHub and spread that opinion?

  • dr.vinmantoo dr.vinmantoo Apr 7, 2016 1:33 AM Flag

    Yes I have an agenda, I hate pumping liars just as much as I have lying shorts. Coolhandlucy seems incapable of facing reality. The comments by the so called bashers have been accurate. The comments by longs (lying pumpers) have been complete nonsense. I haven't posted a single lie or anything that isn't consistent with FDA policy.

    This is the reality. Sunrise is dead. It was stopped at the first futility analysis. The lying pumpers are saying the control arm had better survival than any control arm in history, which is absolute nonsense and a lie since they haven't see the data. Moreover, it is completely irrelevant even if it were true. Sunrise was a controlled trial and the control arm is the the reference point for assessing whether Bavi was effective. The FDA will not drop the control arm, as some lying pumpers post, to enable Bavi to get FDA approval fro Sunrise. That comment is possibly one of the stupidest comments I have ever run across. I like to read the IHub board for laughs and I wasn't disappointed today. laughs. Another lying pumper actually said the data from pre-clinical trials, phase I, the corrupted phase II and the failed phase III will be pooled to get FDA approval for Bavi in NSCLC. You just can't make up stupid like that.

  • dr.vinmantoo dr.vinmantoo Apr 7, 2016 1:45 AM Flag

    poor lucy can't handle the truth.

    {{They do have an agenda for being here, other then the fact they are not allowed to post their lies on IH.}}

    My agenda is to counter lies, whether by pumpers or bashers. I haven't posted a single lie here or on IHub. The pumpers posts in their panic invent even more absurd lies each day.

    {{I say we expose them for who they are, right learningcurve a la stoneroad. And Johnson (sick) you better get yourself some high complex carbs in you kid. I'll volunteer to send you some rice and Idaho potato, you know goat food. Anyway, while we wait for the legal work to settle they, (the bullies) know we, (the real sh holders) will remain range bound. An ongoing investigation is going to do that to the sp every time, again they know this.}}

    Lucy, you have only succeeded in exposing yourself as a hysterical fool.

    {{The company can not and will not comment or divulge anything that concerns the investigation. That would literally jeopardize it.}}

    What investigation? The Sunrise trial is dead. Are you talking about the laughable delusion that big pharma has conspired to sabotage the Bavi phase II and phase III trails?? PPHM could be bought for a rounding error in their budgets but the pumpers want everyone to believe they would risk sabotaging a drug that has repeatadly failed in trials.

    {{Regardless Dr. Garnett WILL speak when his time comes and will silence the naysayers forever!
    So be our guest, post your insults and your LOL's but remember, the last laugh will be on you.}}

    Garnick can talk all he wants but Sunrise is dead, dead, DEAD. The most likely thing that will happen is that Garnick will leave PPHM, and soon. I will continue to post the truth and continue to insult pumpers who lie, or critics who lie. There is a lot of laughing going on, and all of it at your expense.

  • dr.vinmantoo dr.vinmantoo Mar 14, 2016 12:59 PM Flag

    PPHM is back to square zero with pre-clinical models and cell lines, yet PPHM longs are excited.

  • dr.vinmantoo dr.vinmantoo Apr 2, 2016 1:04 PM Flag

    Below is what I posted on the Ihub PPHM but it was quickly deleted. Can the moderators can be sued for fraud or for being a boiler room type operation? They allow or post delusions and outright lies as long as they tout PPHM's prospects. In contrast, any facts which counter that scenario are deleted.

    {{If the Bavi arm has an MOS of 14 months or better from the body of the fully blinded data that was available in February 2016, Garnick just might be able to get Bavi plus Doce FDA approved. }}

    You have to be kidding. This isn't a debating club where you can make brilliant or emotionally moving points to come away a winner. The NSCLC phase III trial of Bavi+DOC vs DOC has been stopped for futility and it is dead. I will repeat because it seems some people can't handle reality. Bavi + Doc failed in the phase III trial. The drug combination failed and the trial failed. PPHM has nothing to bring to the FDA for approval, and will never have anything to go to the FDA for approval based on Sunrise.

    Sure PPHM can look over the data and desperately look for any sub-group that might have seemed to benefit. They can think about starting a NEW trial to test whether such a correlation, if it exists, is more than a correlation. They will have to convince the FDA to allow it, which depends on there not being safety issues arising in Sunrise. Of course they will need to scrape up the money for a new trial but PPHM doesn't have the money for anything more than maybe a small phase II trial. Even if they do all that, it might take a year to start it.

    PPHM management is horrid. I stated on this board after it was revealed that the small NSCLC trials was corrupted and had significant numbers of dropouts/lost patients, that the prudent move would have been to rerun the phase II using a larger number of patients. Instead PPHM was reckless and moved into a large phase III trial without either solid data to base in on or a partner to help finance it.

  • dr.vinmantoo dr.vinmantoo Mar 11, 2016 12:21 PM Flag

    The child-like faith of PPHM longs is amazing. Bavi keeps failing in trials as a single agent or in a combo regimen. The PPHM longs look at that record of failure and say they are the victims of a broad based conspiracy by big pharma to keep their wonder drug off the market, or they were just unlucky.

    As far as this jeff4iam4, you better wake up son.

    {{Do you understand that the Bavi plus Doce group did very well?...that they performed as expected which was showing much greater improvement over historical norms of decades old data of treatments using Doce. However, the trial arm using Doce alone in the Sunrise trial outperformed the historical norms...by a lot. }}

    You know NOTHING of the sort. PPHM and their weasel management put out some BS to that effect in the immediate aftermath of the Sunrise trial stoppage for futility (i.e. FAILURE). You have never seen that data and the CC didn't mention it either. How naive are you? PT Barnum was right, there IS a sucker born every minute. Lincoln was right too. You CAN fool SOME of the people ALL of the time.

  • Reply to

    Hilarious to see

    by brad_pitts_betterlooking_brother Mar 31, 2016 12:00 PM
    dr.vinmantoo dr.vinmantoo Mar 31, 2016 12:50 PM Flag

    Exactly. Someone on Ihub posted this comment, which is being spewed by several longs.

    {{If the Bavi arm has an MOS of 14 months or better from the body of the fully blinded data that was available in February 2016, Garnick just might be able to get Bavi plus Doce FDA approved. }}

    I responded with the follwoing, but it was dleted very quickly.

    You have to be kidding. This isn't a debating club where you can make brilliant or emotionally moving points to come away a winner. The NSCLC phase III trial of Bavi+DOC vs DOC has been stopped for futility and it is dead. I will repeat because it seems some people can't handle reality. Bavi + Doc failed in the phase III trial. The drug combination failed and the trial failed. PPHM has nothing to bring to the FDA for approval, and will never have anything to go to the FDA for approval based on Sunrise.

    Sure PPHM can look over the data and desperately look for any sub-group that might have seemed to benefit. They can think about starting a NEW trial to test whether such a correlation, if it exists, is more than a correlation. They will have to convince the FDA to allow it, which depends on there not being safety issues arising in Sunrise. Of course they will need to scrape up the money for a new trial but PPHM doesn't have the money for anything more than maybe a small phase II trial. Even if they do all that, it might take a year to start it.

    PPHM management is horrid. I stated on this board after it was revealed that the small NSCLC trials was corrupted and had significant numbers of dropouts/lost patients, that the prudent move would have been to rerun the phase II using a larger number of patients. Instead PPHM was reckless and moved into a large phase III trial without either solid data to base in on or a partner to help finance it. That is how you get to $0.40 and facing disaster in a 1:10 reverse split and delisting from the Russell Index.

  • dr.vinmantoo dr.vinmantoo Mar 14, 2016 1:06 PM Flag

    I have posted several times on the PPHM ihub board but my post always get deleted very quickly. That is how the faithful maintain their cults, suppressing any opinions that disagree with their premise. What a sad group of people they are there.

  • Reply to

    IHub

    by jnj1223 Apr 16, 2016 1:49 PM
    dr.vinmantoo dr.vinmantoo Apr 16, 2016 2:46 PM Flag

    Ha, ha. I do post on IHub but the shameless pumpers immediately delete my posts. I sometimes post here so that my comments don't get deleted merely because they counter the fictions being promulgated on IHub.

    North40000 wrote this in his attempt to paint PPHM in a rosy light.

    {{{I'd say the meat on the bone began with Stanford and UCSF and a coincidence that Memorial Sloan Kettering picks up $250 Million from Sean Parker ? I doubt it... and you guess correctly, PS Targeting at play within UCSF, Stanford and MSK...etc..etc}}}

    I responded with;

    Parker is NOT giving the money to Memorial Sloan Kettering alone, and the money is certainly not focused on PS or Bavi. Having someone outside the scientific research community donating significant sums of money is great and welcome news, as it the so-called moonshot by the US government. It will slightly help ease the burden that researcher have on raising grant funds.

    However, I think it says more about how naive these donors are when they talk about how they will revolutionize research and dramatically improve collaboration among scientists. It think it was Paul Allen, the INTEL big shot who waded into the prostate cancer field with donations. He was critical of the research methodology, saying his donation would revolutionize treatments along the lines of what they did at INTEL to continually improve integrated chips. It was truly naive statement as with chips, you are dealing with well defined laws of physics. With cancer, we are dealing with our best guesses at the time, but we are fully aware there is so much we don't know. MicroRNA regulation was unheard of about 10 years ago but is now considered as part of a major cellular regulatory mechanism, not just in cancer and cell division, but in development and cellular homeostasis. It is also clear that cancer cells have multiple mechanisms to bypass and adapt to disruptive strategies.

  • dr.vinmantoo dr.vinmantoo Apr 16, 2016 2:22 PM Flag

    This is what passes for offensive and immediately deleted on IHub. The pumper king North40000 posted this nonsense.

    [quote]"a failed phase III"? Study is continuing or ongoing, not recruiting more participants. Ethics requires following those who have not evented or otherwise disappeared.[/quote]

    I wrote the truth, "The Sunrise trial is as dead as can be. PPHM can continue to monitor those who were treated in the trial, and people who were treated with Bavi were given the option to continue being treated. That is it. The trial is, dead, dead, dead. This is basic biotech investing 101 so any failure to accept that reality is very telling. Whether or not you feel than Bavi has some life left in it as part of some immune modulation combination is a completely separate issue. "

  • Reply to

    just took a pretty big position here

    by lerm14 Mar 11, 2016 1:28 PM
    dr.vinmantoo dr.vinmantoo Mar 11, 2016 6:33 PM Flag

    rabies, are you just pretending, or are you really a fool?

    {{If the bashers have it their way, a reverse split is what they are banking on}}

    The sunrise trial was shut down because it failed the first futility analysis. Bavi is now on hold across the board. The stock cratered and PPHM will need a reverse split or say 1:10 to get to over $1 and keep it there for a while.

    {{I think there will be more information pertaining to the Sunrise trial and other chemo combo trials before the first 180 day delisting deadline. They have already told us the Bavituximab/Docetaxel combo performed as expected (which means it followed suite of the phase II study and doubled MOS rates over the before seen results of the control arm Docetaxel only.}}

    What sheer nonsense! Nobody has a reliable estimate for what to expect for Bavi + Doc because the phase II trial in NSCLC was small, corrupted and had a high frequency of dropouts.

    {{The problem with the Sunrise trial is the control group, Docetaxel/Placebo also doubled MOS rates. They didn't officially say that it doubled MOS rates, but they did say the control arm was "way off the charts" and "never before seen data". If the chemo/combination trials resume after their internal investigation, or if the FDA were to approve anything, delisting won't be in the cards}}

    Management has been full of #$%$ for a long time. Stop with the doubling of MOS fantasy. You haven't seen any data because PPHM hasn't presented any data in their press releases, in their recent CC nor have they hinted they will report the data at an upcoming meeting.

    What internal investigation?

    Why in the world are mentioning FDA approval when the Sunrise trial was just halted at the earliest possible point in the trial for futility?

  • dr.vinmantoo dr.vinmantoo Mar 28, 2016 8:20 PM Flag

    {{No you are wrong! This price is the PERFECT price to ADD not sell! }}

    Right, the bankruptcy courts of filled with people who thought as you do.

    {{What part of the "I'm in at 0.48" did you not get. With my resent add of 20,000 @ 0.40 I have hedged by position down to 0.45 average per share. }}

    I understand perfectly well the blunder you have made. You never heard of PPHM until recently but decided it is a great place to invest so you are only down 13% in a few days. This was an investment in a company whose phase III trial they were banking on failed miserably. Moreover, the data was so troubling that PPHM stopped every trial in progress.

    {{Selling and then buying back at a lower price is a losers game. Accumulation is the name of the game}}

    Right, the bankruptcy courts of filled with people who thought as you do. The time to have gotten some or all out was when Opdivo was approved for NSCLC. Even now a prudent move would be to exit most if not all so that you can preserve what is left of your capital. Now if you were some kind of day trader looking for a dead-cat bounce you might have a point. The idea that someone who calls themselves an investor would load up now is ludicrous.

  • dr.vinmantoo dr.vinmantoo Mar 17, 2016 9:20 PM Flag

    The worst moron on earth may be this biopharm clown on IHub. Even now he is frantically and repeatedly posting how great Bavi is and how great an investment PPHM is. It is bad enough that he is too stupid to face reality, but he is attempting to draw in or keep in gullible people into losing even more money on PPHM. He is one of those repeating the bs that Sunrise was sabotaged and the control arm performed better that in any trial in history. Do he doesn't state the latter directly, he makes it possible for others to spread that bs by keeping their posts up, while deleting posts challenging both of those absurd ideas.

  • dr.vinmantoo dr.vinmantoo Mar 18, 2016 12:26 PM Flag

    I took a look at the IHub PPHM board last night and the delusional spins being weaved there are just too stunning for words to accurately describe. Thankfully, lemmy and carboat are taking the time to try and beat some sense into people there. I like when someone links to the PPHMM CC from two years ago, when management was promoting multiple partners were imminent. Why don't their posts get deleted like all other challenging the delusion?

  • Reply to

    Trial Data

    by rabies_00 Apr 20, 2016 3:35 PM
    dr.vinmantoo dr.vinmantoo Apr 23, 2016 1:46 PM Flag

    Brad,

    {{Vinny since you can post on the Hump could you ask the favored few over there who actually get replies from IR to ask them where the he11 Garnick is and why has he not updated on Sunrise himself? Is he still associated with PPHM in the same manner as before and during the trial or has something changed since?}}

    it looks like Carboat and corporalagarn (love than screen alias) are already doing that repeatedly. They are both quite amusing. It will be funny to watch the pumper longs who have been spewing the "In Garnick we trust" mantra quickly trash him once PPHM acknowledges he is gone. Based on PPHM's modus operandi, I expect that his name will be quietly removed for the web site without any PR.

  • dr.vinmantoo dr.vinmantoo Apr 16, 2016 1:35 PM Flag

    Lucy, there is a very basic test that will show whether you are an ignorant and shameless pumper, or merely a long who is hurting because they suffered financial loss by the latest PPHM price drop.

    Is the Sunrise trial dead?

    Yes or no?

  • dr.vinmantoo dr.vinmantoo Apr 16, 2016 2:33 PM Flag

    Lucy, see there is your problem in a nutsthell. You deny reality on several issues.

    {{vinmantoo, I do not see only black and white as your question directs me to! }}

    What you see or what to see is irrelevant. It IS a black and white picture. Sunrise is dead as the trial has been stopped at the first futility analysis. PPHM will continue to monitor those who were treated as is tsanrd for stopped trials, but that won't change the reality of the trial being dead.

    {{Firstly, what retail sh holder would want to be called "ignorant and shameless pumper" I would say none to answer that question.}}

    Whether one likes it or not, that is what one is if they continue to spew the fiction that Sunrise is not dead. I don't call you an ignorant and shameless pumper, I asked if you would join their ranks by spewing the fiction that the Sunrise trial is not dead.

    {{Secondly, I will admit to being a long, but certainly NOT hurting and not even on paper.}}

    Losing money hurts everyone, but to varying degrees depending on how much money you can afford to lose vs how much you have already lost on PPHM.

    {{ Average down, you've heard of that and that is my choice.}}

    Do whatever you like. It is your money.

    {{And as far as "suffering loss" I will never be in this category! WHY, because I see more then black or white. It's your choice to NOT open your eyes to the prismatic panoramic view. Choose to be drab and jaded and you will never see what you truly possess.}}

    More power to you if you have so much money that you can lose as much as you like on PPHM and not blink an eye. Are you related to Warren Buffett? The rest of your comment is truly laughable, and smacks of delusion. I look at trial results with a calm, rational and realistic eye. You think your wishes and hopes are what matter. Get real.

  • dr.vinmantoo dr.vinmantoo Apr 16, 2016 3:23 PM Flag

    {{Your trying too hard vin man...You will not get me or other longs to relinquish our sh.}}

    First of all , it is "you're" not "your". Second, I don;t care what you do in terms of buying or selling PPHM or any other stock. I do care about the truth and that is why I have posted on PPHM yahoo and IHub boards. I despise those who shamelessly pump and lie. It am only posting the truth, which people like you can't handle. I didn't mention whether PPHM has a shot because of a role as an immune-modulator. I focused on Sunrise and the undeniable reality that it is dead. You want to make it into something else.

    {{Now I have a life to live, if you will excuse me.}}

    Have a great day, a great weekend and a great rest of your life. I will do the same. One word of advice, try not to avoid reality because it is unpleasant and because you hoped for a different outcome. You are not Dorothy in the Wizard of Oz wishing for something while wearing Ruby Slippers.

  • Reply to

    Trial Data

    by rabies_00 Apr 20, 2016 3:35 PM
    dr.vinmantoo dr.vinmantoo Apr 23, 2016 1:40 PM Flag

    Jeff, you also wrote {{What I am banking on is that PPHM eventually makes a partnering deal to push forward with I/O combo trials that I believe will be successful. I am hopeful that a partnership deal will be finalized prior to the ASM or soon thereafter. Without that, it would appear that we current shareholders will likely have to suffer through another R/S and thus be further diluted to the point that the most we can hope for will be a meager profit and that will not be seen for at least several more years. And yes, I will likely wait for it and not sell any of my shares}}

    Do whatever you like with your shares and base it on whatever hopes you have for Bavi in immune modulator trials. I will repeat what I wrote before. As far as combinations with immune modulators, that is field and growing more and more crowded each day. Companies with big money are using combinations of drugs they own, and where each drug on its own has shown efficacy on its own so they are looking for synergism. There is ZERO clinical data for Bavi having good efficacy as a single agent and ZERO clinical data for Bavi in an combination with an immune modulator. Yet for some reason you are confident it will shine. No FUD for you like there is none for other pumpers. Good luck to you. You will need it!

    You actually think PPHM will be able to get a partnership deal soon. Let's be clear about what a normal investor considers a partnership. It is not where PPHM pays someone else to include Bavi in any pre-clinicial studies or clinical trials. It is where another company agrees to pay PPHM significant up front money, say over at least $20 million, provides for significant milestones far in excess of upfront money, and takes over much if not all the developmental costs and grants PPHM a percentage of future sales. I predict that PPHM won't be involved in such a deal this year. What say you?

  • Reply to

    Trial Data

    by rabies_00 Apr 20, 2016 3:35 PM
    dr.vinmantoo dr.vinmantoo Apr 21, 2016 12:20 PM Flag

    {{Dr Pepper and others seem to be hung up on some childishly perceived notion that complete trial data should be released prior to the conclusion of a trial. WRONG! It would be highly unethical to release full figured results during a first look in PR. }}

    You have got to be joking. Releasing an analysis of the data at first look-in is certainly NOT unethical as the trial is over. What IS unethical is longs fawning over the PR then claiming it that they have no doubts or worries because it proves Bavi works, and that the Sunrise data will be the basis for FDA approval when the FDA throws out the control arm. What kind of morons ridicule FUD (fear, uncertainty and doubt) after a flameout as spectacular as Bavi just experienced? No, the pumpers need to stop fawning over a PR which carries zero weight and stop denying that Sunrise is not only merely dead, but most sincerely dead. If they want to point to the PR as proof of how wonderful Bavi is, then they need the data to back it up or #$%$.

    {{The press release was done flawlessly and Peregrine continues to flaunt the link to it on their home page. }}

    Of course PPHM has that PR on their web site. They have nothing else to say. The press release is a piece of fluff with no data, but is designed to try make appear to uninformed investors that the failed Sunrise trial it isn't an utter and complete failure. Apparently that tactic has worked on you, and a few others. By the way, the PR is vague and has lots of wiggle room in it since it contains NO data.

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