You really are an idiot. Given multiple chances to show that you know what you are talking about, you have fallen on your face again. But please, enlighten me -- what is P2B?
My suggestion is that you should listen to those individuals who are knowledgeable about research trial design as well as the science of Alzheimers -- they are the ones who can provide answers on why the trial gave the results that it did. I don't see why people have to be "stand up guys" -- if Esoteric wants to say nothing, that is his right.
We know. Get help, Marat. Hire a nerd high school senior to help you out.
The fact that you can't seem to find any articles on metals and dyshomeostasis from relevant databases only testifies to your basic research incompetence.
And you idea that cognition is NOT a primary endpoint for a HD drug is stupid as well. It is an important endpoint, but improvements in cognition only address PART of the HD solution.
And your idea that the Tanzi lab has done no serious research is laughable. Where do you get your ideas?
This is a such a stupid claim. Do you really want us, lemming like, to rush around and act as your research assistant on this because you make these claims? Look yourself -- there's plenty out there to find. Hint -- start looking for articles on metals and dyshomeostasis.
I get tired of people, on biotech forums or elsewhere, accuse others of soft bashing. Look, the results are disappointing. Simple as that. But this is not the end of the world. Having been in since 2011, I sold a grand total of 1/3 of my shares on hearing of results. I am holding 2/3. So far I have over 200% in realized gains. Don't call this BS -- it is people, disappointed. As for me -- I'm not going to be morose about PRAN, I am looking forward to what they say is the path forward.
Correction to my point -- as an extension trial, there will be no placebo, duh . . . Anyhow, the other arm may show results that are interesting. . . we shall see.
Excellent point. In particular, the odd interim placebo results may resolve themselves by the final results.
No, they have a pipeline - -- PBT434 for Parkinsons is in early trials, for example -- but realizing the benefits of that pipeline will take years. The closest to market is possibly PBT2 for Huntington's.
Good advice. I will hold 1/2 at least -- HD, Parkinson's etc is still on the horizon . . . but the path there might be rocky.
Neshua10, congratulations -- you have just shown that you have the statistical brilliance of AF.
Hi inversor. I see our friend Eso hasn't shown his face . . . :) Hope that you are doing fine. I am -- don't like losing $100,000 in unrealized gains, but I will actually come out ahead on this on realized gains because I sold 1/3 on the way up.
He said to inverso and me that we'd be idiots to sell at $20 post results -- perhaps we can all sell to him at $20?
Look, if you make some bad trades but many good ones, she should be happy. But I never invest what I can't reasonably lose. I'm still ahead on PRAN -- I sold on the way up as well, paid no attention to Esoteric's idiotic rants not to do so --
Why is she letting you invest her money in something she does not believe in? She should not have done that, and you should not have played with her money.