octopus is actually ancient greek. but now we talk american so its 'octopuses' and pretending it has anything to do with latin is a mistake like you said. the riddle really only time will tell.... octopussies or octopoopoo? ill go with the former
i understand it as patent coverage of linker technology binding to albumin in the body, as opposed to a conjugate bonded outside the body in a beaker or whatnot. whats that moron say every evening?? BUY-BUY-BUY... I'm in
An excerpt from Patent 8,153,581 .. I interpret this as the patent protecting the protein binding agent in the body, they also list other chemo they can use i believe. ::: These known protein conjugates are prepared either by coupling the cytostatic agent to the serum protein ex vivo in a “one pot method” (DE 41 22 210 A 1), and isolating the resulting albumin-cytostatic agent conjugate, or by firstly derivatizing the cytostatic agent with a suitable spacer molecule, isolating the resulting product and, in a second step, coupling the cytostatic agent which has been derivatized in this way to the protein by way of a maleimide group (DE 196 36 889 A1 and PCT/DE 97/02000) and then isolating the resulting albumin-cytostatic agent conjugate. Both methods suffer from the disadvantage that they use plasma proteins, which may contain pathogens. Other disadvantages of the above-described protein-active compound conjugates are their unsatisfactory stability and shelf-life and the technical input required for preparing them.
The invention is based on the surprising observation that it is not necessary, as had previously been assumed, to link an active compound to a particular carrier under defined conditions and then to administer the product but that, on the contrary, it is possible to employ therapeutically and/or diagnostically effective substances, which consist of a pharmacological active compound and at least one protein-binding molecular moiety, which are linked to each other by way of a spacer, directly as injectable medicaments since these medic-aments, after having been brought into contact with the body, bind covalently, by way of the protein-binding molecule, to body fluid or tissue constituents, predominantly to serum proteins, such that a transport form of the active compound is created in vivo, which transport form reaches the cells or the tissue which is/are the target of the active compound.
Yea thats what everyone said when they did the offering last yr at 6$. I just shorted 50,000 shares at 3.23 tho im gona make so much money....
oxo sounds more ignorant than the writer of the SA article. referencing a article with pathetic questions and zero facts or answers. the GBM data wasn't mature enough to specify everything and they will be bringing the data to ASCO which will be under embargo. now go back under your rock. keep dreaming that a promotion team rumor will keep BP from scooping this company. richard pearson has balls in his mouth.