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Neuralstem, Inc. Message Board

errico51 16 posts  |  Last Activity: Jul 4, 2014 12:49 PM Member since: Sep 16, 2004
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  • Google, read and hold. Time will tell.

    Sentiment: Strong Buy

  • Reply to

    Ted Harada right to try on Atlanta Journal

    by errico51 May 10, 2014 10:43 AM
    errico51 errico51 May 10, 2014 11:05 AM Flag

    In 2010, after experiencing weakness in my legs and hands, I found myself at Emory University Hospital sitting across from one of the foremost neurologists in the world. My wife and I sat in disbelief as our world was turned upside down. The doctor explained to us that I had ALS, or Lou Gehrig’s disease. The chilling words — “There is no known cause, and no known cure” — continue to reverberate through my head.
    I was 38. I was facing a future without hope, until I had a chance to exercise my “right to try,” thanks to Emory University and their partnership with Neuralstem Inc.

    A groundbreaking safety study was taking place at Emory involving the injection of neural stem cells directly into the grey matter of ALS patients’ spinal cords. I was told it was only to prove it was safe, that it was very risky, and that it most likely wouldn’t help me. I gave my informed consent to participate.

    Then the most unexpected thing happened. It helped.

    Weeks after invasive surgery, I put down my cane and regained strength throughout my body. Empirical data showed that while I was not cured, they could document me regaining strength. You can only imagine the depth of my family’s joy and happiness, all because we had the “right to try.”

    The Goldwater Institute has crafted “Right to Try” legislation that four states are in the midst of passing and eight others are considering. “Right to Try” allows a patient access to investigational medications that have passed basic safety tests without interference by the government when certain conditions are met:

    1.) Patient has been diagnosed with a terminal disease;

    2.) Patient has considered all available treatment options;

    3.) Patient’s doctor has recommended the investigational drug, device or biological product represents the patient’s best chance at survival;

    4.) Patients or their guardians have provided informed consent;

    5.) The sponsoring company chooses to make the investigational drug available to patients outside the clinical trial.

    I am making it my personal mission to introduce “Right to Try” to the Georgia General Assembly as part of next year’s legislative session. Everyone deserves hope and the opportunity to “try.” Can anything be more inhumane than forcing people to endure a fatal plane crash because the onboard parachutes weren’t approved by a federal agency?

    This scenario plays out in medicine daily. I appreciate that the FDA is the gold standard in drug safety; however, if you or a loved one were facing mortality, would you be willing to settle for a silver standard?

    The research and results of the safety and potential efficacy of this research has gone global. A small glimmer of hope, a commodity previously nonexistent in the ALS community, has been ignited. I regularly receive emails requesting help from people throughout the world.

    The desperation is not unique. According to the Goldwater Institute, “More than 500,000 Americans died last year of cancer alone, and thousands more of other terminal illness. Promising treatments exist that could save their lives, but it takes a decade and a billion dollars for a drug to reach full FDA approval. Only 3 percent of the sickest Americans qualify for clinical trials, and the FDA protocol for approving drugs has not changed in 50 years.”

    Through my advocacy efforts, I have learned that only an average of 27 new drugs are approved by the FDA on an annual basis. They could be for acne, arthritis or anemia. Typically, very few of them are for diseases that have no cure, such as ALS or virulent forms of cancer. This leads sufferers to risky and potentially fraudulent “treatments” that may cost tens to hundreds of thousands of dollars..

    If you believe as I do, that patients in Georgia deserve the right to try, then please reach out to state legislators and tell them to introduce and pass “Right to Try” legislation next session. Trying will not be enough. That right should be reserved for people dying without hope.

    Sentiment: Strong Buy

  • Reply to

    Right to Try

    by teo_099 May 17, 2014 4:42 PM
    errico51 errico51 May 17, 2014 4:45 PM Flag

    Bill passed in Colorado

    Sentiment: Strong Buy

  • Reply to

    Thomson Reuters Bioworld Story on Neuralstem

    by rjwinger May 23, 2014 1:13 PM
    errico51 errico51 May 23, 2014 1:32 PM Flag

    Great News

    Sentiment: Strong Buy

  • errico51 errico51 May 28, 2014 12:30 PM Flag

    I own both and a massive confidence in Robert Lanza ACTC in very long term, while Cur is very close to explode

    Sentiment: Strong Buy

  • Lab receives matching gifts for Alzheimer’s research
    Groundbreaking research on a devastating neurological disorder – Alzheimer’s disease – will reach the fast track in the Program for Neurology Research & Development this year, thanks to matching $250,000 gifts from the Sinai Medical Staff Foundation and the Richard & Jane Manoogian Foundation.

    “I cannot overstate the importance of generous gifts like these in advancing the cause of medical science,” said PNR&D Director Eva L. Feldman, M.D., Ph.D. “Often times the NIH shies away from funding high-risk research despite its potential to yield high rewards. It is crucial that private philanthropy get the ball rolling on this important work, and that is exactly what these two forward-looking foundations have accomplished.”

    The gifts, which will be distributed over five years, will support stem-cell work under way in the Program for Neurology Research & Development. Dr. Feldman is well into Phase 2 of a clinical trial that is testing the effectiveness of stem cells in ALS patients. Phase 1 results were published in March and showed that humans tolerated the stem cell injections well. The PNR&D has already begun adapting its ALS stem cell work to learning more about Alzheimer’s.

    Alzheimer’s disease affects more than 5 million Americans, two-thirds of whom are women, and the emotional toll it exacts on family members and loved ones is immeasurable. The direct cost of caring for sufferers of Alzheimer’s will total $214 billion in 2014, and the Alzheimer’s Association estimates that 15.5 million family members and friends provided 17.7 billion hours of unpaid care to dementia patients – care valued at an additional $220 billion.

    “We have made tremendous progress in stem-cell research, particularly in the area of ALS, or Lou Gehrig’s disease,” Dr. Feldman said. “Because of what we’ve learned from our human clinical trial for ALS, we are now able to translate those techniques and direct our attention to another devastating neurological disorder: Alzheimer’s. I cannot overstate the importance of generous gifts like these in advancing the cause of medical science.”

    Share this:

    Clinical Trials

    Lab receives matching gifts for Alzheimer’s research
    Success of ALS clinical trial builds promise for neural stem cell therapies
    11 Taubman Scholars named among America’s best doctors
    Dr. Feldman paired with artist in ‘Art and Science’ fundraiser
    Taubman, Feldman receive ALSA Michigan Legacy of Hope Award

    University of Michigan Stem Cell Research
    Center for Stem Cell Biology
    Michigan Center for Human Embryonic Stem Cell Research
    International Society for Stem Cell Research

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    Sentiment: Strong Buy

  • Reply to

    From Taubman Institute

    by errico51 May 31, 2014 12:20 PM
    errico51 errico51 May 31, 2014 1:59 PM Flag

    Really amazing from Dr. Eva Feldman:
    “We have made tremendous progress in stem-cell research, particularly in the area of ALS, or Lou Gehrig’s disease,” Dr. Feldman said. “Because of what we’ve learned from our human clinical trial for ALS, we are now able to translate those techniques and direct our attention to another devastating neurological disorder: Alzheimer’s."

    Sentiment: Strong Buy

  • So much to catch up on! So much has been happening from graduations to lemonade stands to 4 hour row-a-thons. Kyle recently graduated from the Air Force Academy and we had a terrific weekend with friends and family who all came to celebrate and fry 7,000 feet closer to the sun. Unfortunately my dad was unable to fly out as he’s very busy at Spaulding rehab hospital. I haven’t seen him since the first surgery, so I was thrilled to finally be with him again. He’s got a nice room overlooking the Boston harbor, and his bulletin board is covered in notes, pictures, medals, trout bandanas, and pug drawings. image. The facility is extremely beautiful and brand new, equipped with state of the art technology and equipment. During the day he uses a motorized wheelchair to get around. He steers it by tilting and pressing his head on the neck rest. Sometimes this results in bumping into walls, running over toes, and tipping off the edges of sidewalks. When he’s done with the wheelchair for the day, he is literally air lifted out of it and into bed using a ceiling crane and a body sling. Like those videos of whales getting picked up off the ground and into truck beds.
    In bed he watches The Colbert Report and The Daily Show nightly. We feed him his dinner and he swallows a plethora of meds. Sometimes he sits and uses his Tobii- a tablet that uses eye tracking technology to allow him to surf the web, watch YouTube, or send a text. Then the lights turn out and he tries to sleep but it’s very difficult and uncomfortable because he can’t move or position his body how he wants. So he either wakes up whoever is sleeping in the room or calls the nurse to have her push his body on his side, lay his arms out, and reposition his legs and feet. When morning comes the first item on the agenda is iced coffee. One morning a nurse came to clear dad’s breakfast tray and she almost took his cup, and he told her he would bite her arm off if she did so.

    Sentiment: Strong Buy

  • Reply to


    by errico51 Jun 6, 2014 2:39 AM
    errico51 errico51 Jun 6, 2014 2:43 AM Flag

    Working diligently at his side is my mother, who runs the whole show. I spent two days in her shoes; waking up early to get coffee, brushing his teeth, getting him dressed, walking him to his workouts, aiding in those workouts, feeding him his meals, changing the channels, trying not to cringe as he zig zags with his wheelchair, waking up hourly to reposition him and give him water, and it was EXHAUSTING. She does this all while trying to get our house renovated and a wheelchair van in the driveway, keeping track of two kids and two dogs, driving between states daily, and responding to infinite texts and emails. I honestly don’t know how she’s still alive, let alone pulling this off with a smile on her face.That being said, she can really only do this because of the huge support system behind us. Dawn our dog sitter has been graciously keeping Nelly and Olive at her house this whole time, even sometimes bringing the dogs to Boston for visits. Good friends and their good kids hold lemonade stands to raise money for dad and to spread awareness about ALS. My mom’s good friend and dad’s old swimming partner Jill hosted a 4 hour row-a-thon and donated money to the ALS association and our family. Ken set up an account and link on this page to allow people to donate to our family to help offset that tremendous costs of ALS. Dad’s friends flew out for Kyle’s graduation to be there to support him and us. The neighborhood and surf club guys are regular visitors at Spaulding and bring dad good food (and the occasional beer) and ensure the party life still exists in dad’s routine. Friends and strangers drop off meals, flowers, packages, and cards on our doorstep to let us know we’re on their minds. If I were to list the good things everyone has done for us, this post would never end.All of those good people and good things are coming together next Friday at An Evening of Hope, a gala in conjunction with the ALS Association of Rhode Island.

  • Reply to


    by errico51 Jun 6, 2014 2:39 AM
    errico51 errico51 Jun 6, 2014 2:47 AM Flag

    Our friends and their staff have planned an exquisite and what sounds to be a wildly successful event. Dad will be there and is extremely excited, though he does have to be back at Spaulding that night (so don’t give him too much wine!). He and I sat down and wrote a speech, him talking and myself typing, that he’ll deliver that night. I’m warning you now, ladies wear waterproof mascara and guys have plenty of tissues on hand. He’s finally got the chance to tell everyone how this disease has affected him, and what he’s got to say is truly moving.

    Sentiment: Strong Buy

  • Reply to

    News Story About Kreg Palko with video

    by velopismo Jun 13, 2014 3:23 PM
    errico51 errico51 Jun 13, 2014 4:15 PM Flag

    Link twitter with Ted Harada and you will find

    Sentiment: Strong Buy

  • errico51 by errico51 Jun 17, 2014 10:12 AM Flag

    Good sign IMO to reach the moon.

    Sentiment: Strong Buy

  • Reply to

    what is the reason

    by adel7 Jun 26, 2014 7:56 AM
    errico51 errico51 Jun 26, 2014 8:40 AM Flag

    You forget the real winner in the space: CUR. ACTC with this new management will be in the long term another gem.

    Sentiment: Strong Buy

  • errico51 by errico51 Jun 27, 2014 1:47 AM Flag

    "The latter will utilize cutting-edge stem cell research and treatment practices that are much faster and hopefully more successful than today's standard approaches. The Individualized ALS Treatment Initiative will bring together stem cell experts, doctors, research specialists and experienced pharmaceutical reps to coordinate and facilitate rapid individualized discovery, while completely sharing all data.
    "We believe that through a massive assault on this disease, we can have solutions in the foreseeable future," said Paul Varisco, Gleason's father-in-law, and the executive director of Team Gleason.
    The campaign hopes to raise $500 million through private donations during the next five years to help fund the initiative.

    Sentiment: Strong Buy

  • 26 Jun 2014:
    Amanda and I returned from Baltimore yesterday. I had an appointment at the Hopkins ALS clinic on Tuesday.
    If you visit here frequently or have dealt with ALS in your life, you'll know that body weight and FVC are the two biggest indicators of disease progression.
    My weight has remained steady, since my diagnosis, at approximately 205lbs.
    My breathing has declined. In November 2013 my lung capacity was 53%. In February of this year it had dropped to 48%.
    My FVC on Tuesday was still 48%. I don't know how it has remained the same, but I'm not complaining.

    Sentiment: Strong Buy

  • errico51 errico51 Jul 4, 2014 12:49 PM Flag

    It seems possible when I see the slide of the surgery on his blog but I am not so sure. Goggle Tony Conway blog

    Sentiment: Strong Buy

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