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Endocyte, Inc. Message Board

fib1_1_2_3_5 110 posts  |  Last Activity: Aug 3, 2015 10:10 AM Member since: Dec 8, 2000
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  • Reply to

    Stock repurchase

    by bdj82 Jul 29, 2015 3:13 PM
    fib1_1_2_3_5 fib1_1_2_3_5 Aug 3, 2015 10:10 AM Flag

    As of June 30, DL completed the $2B share buyback started in 2014. This totaled about 44M shares.

    They have just recently authorized a new $5B buyback to complete in '17 (I think).

    The numbers only come out quarterly (go to the 10Q/K and search for "repurchase"). If you really did mean a real time number, I am not aware of any such data.

  • Reply to

    LOL over on IHUB.

    by fib1_1_2_3_5 Aug 2, 2015 8:16 PM
    fib1_1_2_3_5 fib1_1_2_3_5 Aug 2, 2015 8:30 PM Flag

    Well, finally one PPHM long, BioBS, weighed in against the venom. BDU also was anti, but he a vocal short so does not count.

    i would be certain that MD2512 also would be strongly against such, especially as the group attacked him for trying to be reasonable.

    Curious where the others on that board will stand on this disgusting behavour.

  • fib1_1_2_3_5 by fib1_1_2_3_5 Aug 2, 2015 8:16 PM Flag

    Three "respected" posters are having a love fest calling for PPHM non believers (or even partial doubters) to die of cancer.

    Started with volgoat:

    "i'm waiting for the day DEW gets cancer, will be a great day. :)
    and all others that bash cancer companies. Karma is a beotch.
    a slow painful death would be the best case scenario:"

    And supported by eb and couch..

    Curious is wookie will weigh in over here (I assume the IHub posts will soon be gone).

  • fib1_1_2_3_5 fib1_1_2_3_5 Jul 13, 2015 11:41 AM Flag

    I would think the primary endpoint (OR) is already well established and the secondaries are reasonably mature (17 months since last enrollee).

    The timing here slightly puzzles me. I would have thought they would have planned to release the primary OR data months ago, and update PFS/OS as time when by.

    Regardless, agree that we should have data soon.

  • Reply to

    Any update from Jeffries?

    by cjdbs Jun 3, 2015 4:37 PM
    fib1_1_2_3_5 fib1_1_2_3_5 Jun 4, 2015 10:38 AM Flag

    Still saying Q3 for the data from the 2nd P2 for TRV130, but clinical trials .gov says Jun so hopefully it will be within 1-2 months.

    I would suspect late Q3 or Q4 we would hear word on the P3 trial plans for 130 (still saying they hope to start on Q1 '16, but would be nice to hear some more details).

    The heart failure drug (027) is looking at Q1 '16 for data. This one has a go-nogo by their partner which could provide a milestone payment.

    And that is about it for anything that can actually move the stock.

  • Reply to

    V-Pack sale was $230 million

    by boja4 Apr 23, 2015 3:18 PM
    fib1_1_2_3_5 fib1_1_2_3_5 Apr 23, 2015 5:21 PM Flag

    Only about $10M ( and that is next Q).

    But that's a start. Should be at $40M/Q or so by EOY. Add that to cash in hand of about $200M and things are OK by me.

  • Reply to

    MNKD FILED A CT ORDER - 12/15/2014

    by jstokcton Feb 10, 2015 8:41 AM
    fib1_1_2_3_5 fib1_1_2_3_5 Feb 10, 2015 9:05 AM Flag

    CT orders are fairly common, and almost always just mundane details of confidential contracts and such.

  • fib1_1_2_3_5 fib1_1_2_3_5 Feb 6, 2015 10:53 AM Flag

    So, how is it possible for a type 1 to have no more needles?

  • Reply to

    EU royalties

    by iyonwin1 Feb 1, 2015 10:08 AM
    fib1_1_2_3_5 fib1_1_2_3_5 Feb 1, 2015 10:24 PM Flag

    The EU has both 2-DAA and 3-DAA approved. The 2-DAA is for genotype 4. But fir type 1, it will still be the 3-DAA product.

    The FDA label is only 3-DAA because genotype 4 is rare here.

  • Reply to

    A Battle

    by tartiaboy Jan 30, 2015 10:55 AM
    fib1_1_2_3_5 fib1_1_2_3_5 Jan 30, 2015 12:08 PM Flag

    Looks like the opossing force was French :-)

  • Reply to

    Abbv info from the call great.

    by iyonwin1 Jan 30, 2015 9:56 AM
    fib1_1_2_3_5 fib1_1_2_3_5 Jan 30, 2015 12:03 PM Flag

    It was "over $3B", but to be safe $3B seams reasonable. So $150M (to ENTA) there. That does not include Japan though, which is a decent market (with higher roalties). Perhaps another $30M.

    So $180M is very reasonable for '16. Not bad.

  • Reply to

    What FDA dates are we waiting for??

    by vinman2228 Jan 24, 2015 1:11 PM
    fib1_1_2_3_5 fib1_1_2_3_5 Jan 29, 2015 2:23 PM Flag

    That trial finished recruiting by Dec 22 (Dec 8 at the earliest). The trial runs 4 weeks. So give them 2 weeks of slop and a few weeks to scrub and unblind. Looks like March is a good bet, maybe late Feb at the best.

    Also have:

    Chirotic: Oct '15
    Chirotic with portal hypertension: Jul '15

  • Reply to

    25 states worth of Medicaid goes with Vpak

    by fib1_1_2_3_5 Jan 28, 2015 5:54 PM
    fib1_1_2_3_5 fib1_1_2_3_5 Jan 29, 2015 10:31 AM Flag

    Damit, why do you have to spoil my hopes :-)

    I am puzzled why a buying consortium would act individually, but it is the government so who knows.

  • Reply to

    Short interest

    by onemodolar Jan 17, 2015 12:53 PM
    fib1_1_2_3_5 fib1_1_2_3_5 Jan 29, 2015 9:24 AM Flag

    It would not at all suprise me to find out that a substantial portion of the short was now a hedge against to be tendered shares.

    E.G., own 1000s long at $47. Plan to tender for $50, but expect to only get 75% accepted. Therefor one could short 250s against the tendered box to lock in a profit of $3X750. Once the tendor is gone the 250 short is covered by the unaccepted long shares,

    Illegal, but I doubt the SEC would bother wth it.

  • Reply to

    25 states worth of Medicaid goes with Vpak

    by fib1_1_2_3_5 Jan 28, 2015 5:54 PM
    fib1_1_2_3_5 fib1_1_2_3_5 Jan 28, 2015 6:09 PM Flag

    And some quick napkin numbers would make this about a $300M/y deal. This is the 3rd large deal, with a hell of a lot of the pool still unclaimed.

  • dss.moDOTgov/press/150126-missouri-designates-new-hepatitis-c-drug-for-medicaid-patientsDOThtm

    Not too shabby.

    Missouri, as part of 25-state consortium, designates new Hepatitis C drug for Medicaid patients; reaches agreement that will save taxpayers millions of dollars in Fiscal Year 2016
    Viekira to replace Sovaldi as preferred treatment option; pharmaceutical maker to pay rebate to the state
    JEFFERSON CITY, MO – The State of Missouri, as part of a 25-state purchasing consortium that includes Texas, Michigan, and Wisconsin, entered into an agreement on Jan. 22, 2015 to begin using Viekira for Medicaid patients with Hepatitis C who meet certain medical criteria. Viekira was recently approved by the FDA on Dec. 19, 2014.
    Under the agreement reached late last week, the company that makes Viekira, AbbVie, has agreed to provide a rebate to states participating in the consortium. For Missouri, it is estimated that switching to Viekira will reduce overall costs of treating Hepatitis C patients by 30 to 40 percent and result in savings of $4.2 million in Fiscal Year 2016.
    Federal law requires states to make this treatment available to Hepatitis C patients who meet certain medical criteria. Effective immediately, Viekira replaces the drug Sovaldi as the preferred treatment option for Hepatitis C patients enrolled in Missouri’s Medicaid program who meet these criteria.
    Missouri Medicaid patients who have been approved for Sovaldi as of Jan. 1, but have not yet started treatment, will now be prescribed Viekira. Patients who have already begun treatment with Sovaldi will continue to use Sovaldi for the remainder of their treatment. Sovaldi will also continue to be approved for patients for whom Viekira is not an effective substitute, which is estimated to be about 15 to 20 percent of Hepatitis C patients.
    For an able bodied adult in a family of four to be eligible for Medicaid in Missouri, the family must earn less than 19 percent of the federal poverty level, or $4,532 a ye

  • fib1_1_2_3_5 fib1_1_2_3_5 Jan 26, 2015 10:01 AM Flag

    No dilution likely for over a year. They have a decent pile of cash thanks to NVS returning MEK-162. The P3s for Selumetnib are all on AZN, and the P3s for 162 and 818 are almost all on NVS.

    The biggest dilution fear had been that they would push the 2 blood cancer drugs to hard. But this seams unlikely now that they have several shots on goal w/o them.

    Of course the present PPS is a lot higher than 2 weeks ago. But that is another story.

  • Reply to

    Clv

    by bottomfeeder001 Jan 26, 2015 7:20 AM
    fib1_1_2_3_5 fib1_1_2_3_5 Jan 26, 2015 7:25 AM Flag

    Yes. Failure would to do would put it in default and they would owe the fulee $25 (more or less) face value.

  • Reply to

    Could not hold 7 not a good sign

    by worrywartzz Jan 23, 2015 1:17 PM
    fib1_1_2_3_5 fib1_1_2_3_5 Jan 23, 2015 3:16 PM Flag

    Given the huge pop, the ability to hold anywhere near $7 surprised me. I expected a drop back to the mid-low 6's.

    So I see a very strong chart.

  • Reply to

    1 indication not impressive

    by anton11267 Jan 23, 2015 2:37 PM
    fib1_1_2_3_5 fib1_1_2_3_5 Jan 23, 2015 3:03 PM Flag

    EDIT: I meant benimetinib as the other MEK).

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