maybe because your not backing up your PPS estimate with any reasoning ?? Long term bull so hope your right
159 Institutional Holders
66,014,871 Total Shares Held
Value (in 1,000s)
PAULSON & CO. INC. 09/30/2015 9,000,000 3,218,500 55.67 31,140
VANGUARD GROUP INC 12/31/2015 6,587,273 116,566 1.80 22,792
BLACKROCK FUND ADVISORS 12/31/2015 5,310,885 (219,031) (3.96) 18,376
STATE STREET CORP 09/30/2015 5,105,071 3,337,407 188.80 17,664
CITADEL ADVISORS LLC 09/30/2015 3,914,655 3,327,408 566.61 13,545
MILLENNIUM MANAGEMENT LLC 09/30/2015 2,689,859 377,257 16.31 9,307
BLACKROCK INSTITUTIONAL TRUST COMPANY, N.A. 12/31/2015 2,584,484 90,408 3.63 8,942
ORBIMED ADVISORS LLC 09/30/2015 2,276,648 (844,500) (27.06) 7,877
INVESCO LTD. 09/30/2015 2,113,843 (328,021) (13.43) 7,314
FRANKLIN RESOURCES INC 09/30/2015 2,036,467 67,767 3.44 7,046
JPMORGAN CHASE & CO 09/30/2015 1,155,320 830,625 255.82 3,997
There is no way they would mention anything about a partnership or buyout, but they do have very capable people in place with vast experience from major pharma co's , but unless I missed it, nothing was mentioned about how to pay for such an expensive launch of Possibly two drugs later this year ? estimated cost of 250-400m. I do hope dilution of shares is NOT on the table !!
Hope something they say moves the stock up to where it should be trading at, ? like $7-8 . Long SGYP
I'm happy to hold my 11,500 shares knowing that I will make some decent profit on a partnership with a larger company or A LOT of profit with a BO ? but 1 of the 2 options will happen late this year. Don't give up longs or listen to any of the mindless postings here & if you are buying or selling stock based on Yahoo posts your as big of idiots as they are & you should probably be out picking up aluminum cans to make extra money instead!!
Pray for the Fox network to cancel Lucifer before it even airs. And for those people who would make a show celebrating Satan. It is very easy to say “it’s just a television show!” but when it comes to someone’s eternal destiny, it certainly is not. If you are a Christian, reject shows that want to change the image and “brand” of Satan himself while casting God in a negative light. And if you are not a Christian understand that there truly is a battle being waged for your heart, mind and ultimately your soul. Take the time to know God from the Holy Bible, not a TV show or movie – and understand that God does truly love you and wants you to be reconciled to him. And rather than lead you to sin and Hell – He wants to free you from it for eternity.
Sentiment: Strong Sell
The only thing that stinks is you, so hit the shower!! This stock cant go down much farther because too many hedge funds own SGYP & smart investors like myself that understands the fundamentals of the company is holding their shares & only @ a paper loss.
Sentiment: Strong Buy
Because IRWD has had a 5 year head start with Linzess on the market, once the GI doctors start writing prescriptions for Plecanatide sales will increase dramatically, over time sales will outpace IRWD 2to1 . Whoever buys SGYP will have a worldwide sales force in place dedicated to making this happen. Plecanatide is clearly the better drug, its a proven fact & you will hear more about this on the 10th @ the conference in NY!!
Many shareholders know that the success of Linzess has already paved the way for Plecanatide, hence the numerous articles on a highly de-risked investment since no patients has had any major issues with taking any indication of Linzess, but the key difference will be that SGYP will be sold to I'm betting Shire so they will certainly reap the rewards with a much better drug & with higher sales!!! while investors will reap the rewards of a BO premium !! Long SGYP
Its the stock market that's out of whack !! SGYP is doing everything right , they don't control price of oil, fed rates,inflation, jobs, layoffs,market crashes, HFT, violence in other countries, Politician (H C) with 3 brain cells that tweet about price controls for drugs, a smug scientist on trial for BS, or anything else that would cause negative investor reactions regarding their shares of SGYP. Yeah I pay attention jerkyhawk00.
Does anyone think the PPS will finally move higher given the fact that the CIC indications probably will turn out better than expected , any peep of a BO would rocket stock to $15, but doubtful anything will be said so maybe we could see $ 5-6 by close of market. Long SGYP
serial killers have all of those attributes lol My prediction is a $30 BO from Shire then I would make $250k in profit so $45 would be ridiculous profit @ $415k After investing in Bio's for 6 years, it would certainly be a Home Run stock for me as well as many other investors !!! Hope your right ? All the best to Longs
I can see VR being a huge revenue stream because you have these crazy people doing all of these stunts & the normal people would probably pay to see what its like without getting hurt or killed. I can see people with drones shooting footage all over the world & uploading their video for others to watch. Drones will be useful to many ,many people & industries like for security , police , real estate owners & potential buyers, also the media for covering car crashes, or locating lost people & tracking criminals & terrorist . Monetizing all of the data will be key of course but Nick needs to quickly hire some smart visionary people to make GoPro a success instead of buying a yacht & watching lots of crotch. Long GPRO
Yes, you are correct Ronsmithsom54, & I'm on your side lol The clinical trials website showed a CIC study that was estimated to be completed in April 2016, now that has changed, so the only indications that are left is the IBS-C3 12wk study due for completion in July 2016 & the last IBS-C3 12wk study to be completed in Aug 2016. I just looked @ website . So things are moving along good, maybe a late summer BO will finally happen ? Long SGYP
Money to be made on both sides, but I would lean toward AAP with having the most upside potential with a BO price of $210 & ORLY heading to $300 when not if the deal is announced...
Sentiment: Strong Buy
They are 4 years behind, but they will clearly have the better drugs on the market, so sales of Linzess will decline dramatically !! IRWD will not be bankrupt, but their income will decline starting in 2017.
A Shire Buyout Is More Than A Possibility
In a nutshell, there are 4 reasons why Shire would be interested in acquiring Synergy.
•Plecanatide is a complementary asset to Shire's growing portfolio of digestive disorder products.
•Shire's reputation for pricey specialty therapeutics with extensive market exclusivity would put plecanatide in the hands of high prescribing gastroenterologists right off.
•Shire's product revenues, which were flat this past quarter due only to the erosion of Intuniv revenue from generic competition, would receive a big boost.
•And Shire would place a promising late-stage compound into its already long list of pipeline candidates - dolcanatide (formerly SP-333) which could command a huge stake of the Opioid Induced Constipation market valued at $2B annually by AstraZeneca (NYSE:AZN)
Any company willing to buy Synergy Pharmaceuticals will need to have a worldwide sales force already in place and a commercial portfolio that lends itself to easily distributing plecanatide.
Plecanatide is a 16-amino acid peptide that is structurally identical to uroguanylin with the exception of a single amino acid change. This key amino acid substitution provides improved stability and an 8-fold higher binding constant to the GC-C receptor. Taken as a tablet once-a-day, plecanatide, like uroguanylin, operates in a pH-dependent manner, exerting its activity primarily in the upper GI tract to facilitate fluid movement required for regular bowel function. GADZ is long SGYP