Will hold for a longer timefrme now.
Burn injury has been reported to be an important cause of morbidity and mortality in many countries. It leads to a loss of integrity of the skin, which protects us from water loss, temperature change, radiation, trauma and infection. The burn wound is defined in terms of the evolving injury that occurs. In adults, the normal repair of massive full-thickness burns is fibrosis and scarring without any appendages, including hair follicles, sweat and sebaceous glands. Autologous skin grafting followed by application of an elastic bandage has been considered to be a better treatment for excised burn wounds. However, donor sites for autografts are limited in those patients with very large burns. Recently, great progress has been achieved in the research of artificial skin substitutes, however, creating a viable skin substitute by assembling individual components in vitro has not been successful. Furthermore, during the healing process of deep partial or full-thickness burns treated by the known skin substitutes, wound contraction and scar formation are still unavoidable. At present, the substitutes containing stem cells do not only temporarily prevent the loss of body fluids and bacterial infection, but also achieve satisfactory repairing effects. Optimum healing of a burn wound requires a well-orchestrated integration of the complex biological and molecular events of cell migration and proliferation, and of extracellular matrix deposition and remodeling. Stem cell therapy can improve the quality of burn wound healing, reduce the formation of scars and re-establish the normal function of the skin and its appendages.
what don't you understand?
However, it appears as though one is on the way.