It means CERU will not know any results/data until the trial is unblinded. Blinded means just that...they do not know who is getting the CERU's drug and the other drug so they are blinded to the knowing this. The patients don't even know if they are getting the trial drug.
They will communicate results after unblinded.
Yes, as far as reading everything I agree and the studies I have read are not 100% conclusive on cardio issues plus they were with much higher doses.
I'm going against my pessimistic style and focusing on the positives.
Those little brave Critters hopefully will translate well.
I sure in the he ll am not going to bet you a dime. You've been dead on too many times to even think of that.
Leo isn't bad at all.
I was invested in BLRX and ORMP and they seem to try and hide info even when it really is good. Two companies from Israel and they act the same way when data is released.
In the USA, the prevalence of psoriasis was estimated to be around 4.6% while in Canada it was 4.7%. Data from Europe show little variation in countries with a range from 1.4% (Norway), 1.55% (Croatia) and 1.6% (UK). In East Africa, the figure was 0.7% and in the Henan district of China only 0.7% were found affected.
Which brings in Billions for Psoriasis focuses on IL-17.
This would be some huge news is CTIX can lead the way with this oral pill that.
One thing that I have not mentioned about the history of Abacavir is that it may actually Cause inflammation as some studies have indicated as they associate the inflammation with the greater rate of cardiovascular events, but I do believe this is at much higher levels in HIV patients.
Will Prurisol decrease PRINS and IL-20 in humans and if so will this decrease help Psoriasis?
I still believe that Dr. Menon has found something that others have overlooked in Abacavir. Because the Cardio-risks that scientist say "could be" correlated with inflammatory affects from abacavir are well documented and I'm sure he has studied this.
I just can't wait for results ... let's just get it over with!
Yeah, Charley, Just thanked you on another post. That did help ease my slight worries about dose.
Will Tomorrow be News day?
Thanks Charlie ... I always have had trouble computing this stuff, that site helps some of the articles I looked up were confusing to me (as hard as it is to admit) I must be losing my cognition.
One of my concerns was with Dosing and if the dose was going to be efficient as it was 10mg x 2 for mice. I hope the dose is high enough.
Right on Wimusky --- certain groups can make a fortune by hiring him. I wouldn't be surprised if it was Cramer himself stealing money because he sure cannot make much off of The Street.
By the way, there is a Reason why Cramer hired a "Political Science" person as he will already have some "spinning" skills.
Cramer has admitted that he used to "Fabricate" articles and release them to the mass of investors and they would sell based on taking his information for Truth. He is just admitting to being a #$%$ Bag Greedy Person.
I do agree.
AF HAS to be paid illegally for writing bashing articles - obviously I cannot prove this, but have been following him for years. It's just that no one in a position of power has never looked into it or they simply don't care as he attacks smaller cap stocks in which he can Really have an effect on stock price. He is very effective as I have seen him take stocks down 35 -40% in a week and if he doubles down with another article it's not good.
America has become a very corrupt country and most of us do not see it, but our entire political system is based off of corruption. It appears both sides are in it together playing the 'role' of dissension creating the appearance that there is a great difference, but I strongly believe both sides are paid for by the elite and are groomed from a young age. It's all about Greed. Greed is NOT Good if you have to be a criminal to obtain wealth.
Multiple Myeloma and Asthma are two potential candidates.
The real question is how much does reducing PRINS have to solely do with Psoriasis. There is not much DEFINITE information on IL-20 and psoriasis but maybe Dr. Menon has found some quality literature on that.
This could be a base hit, double, triple, home run, or even a grand slam.
In the mouse studies I would have to say it's as close to a grand slam as possible but not seeing any data at all on humans is always a risk.
I wouldn't even take a chance of allowing the word to get out - even on a weekend --- I believe a partnership has Already been talked about and they know exactly what data will bring that to fruition.
That is correct: The average dose of Doxorubicin for STS is 60 to 75 mg/m2 IV once every 21 days and the absolute top of 100mg to 150mg, but average is 60 to 75mg. For this trial it is 75mg every 21 days until tumor progression OR until toxicity. I don't believe we have to worry about Toxicity in Aldox.
So the question is this: Will 260mg of Aldoxorubicn that releases primarily around the tumor be better than 75 mg of Doxorubicin that is circulated all throughout the body?
There are also the other 4 comparative arms: (5 including Doxorubicin)
Dacarbazine administered at 1000 mg/m2 by intravenous infusion (IVI), over 90±15 minutes on Day 1 every 21 days until tumor progression or unacceptable toxicity occurs.
Pazopanib, 800 mg orally each day until tumor progression or unacceptable toxicity occurs.
Gemcitabine, 900 mg/m2 by IVI over 90 minutes on Days 1 and 8, plus docetaxel, 100 mg/m2 by IVI over 1 hour on Day 8 of a 28 day cycle until tumor progression or unacceptable toxicity occurs;
Ifosfamide 2.0 g/m2 administered over 2 to 4 hours on Days 1-4 of a 21 day cycle + mesna per standard site administration regimen until tumor progression or unacceptable toxicity occurs.
LOL, I can't imagine anyone liking her let alone voting for her. She is one Evil lesbo.
Yeah, America could use some I-candy.
On MSNBC Matthews was caught on tape saying "Man I could watch her walk like that all day" referring to Trumps wife... he didn't know his mic was on and was on live tv. Funny.