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Acusphere, Inc. Message Board

grampoptemp 27 posts  |  Last Activity: Apr 21, 2014 6:03 PM Member since: Apr 6, 1999
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  • Reply to

    EMA CHMP upcoming meeting - Next week

    by grampoptemp Apr 16, 2014 10:11 PM
    grampoptemp grampoptemp Apr 21, 2014 6:03 PM Flag

    OK, you win that prize.

    Considering the hazards and risk of radioactive dyes used in the present xray test that Imagify would replace, I have a feeling that the CHMP meeting may be a bit more objective about the benefits of Imagify as a diagnostic, as compared to the potential adverse reactions, which, as I recall, were not life threatening.

    Also, I am wondering as to how the dosage used in the trials was actually determined, or calculated, which might be a way to reduce the seriousness of any side effects, and still get reliable readings.

    Perhaps technology in ultrasonic sound diagnosis has improved in the intervening years, making it more sensitive, and thereby perhaps permitting smaller dosage of Imagify to obtain a reliable diagnosis with less risk.

  • Reply to

    EMA CHMP upcoming meeting - Next week

    by grampoptemp Apr 16, 2014 10:11 PM
    grampoptemp grampoptemp Apr 20, 2014 10:48 PM Flag

    Thanks for the info on the agenda date. As to patience, ACUS is one of the longest tests of my patience, as it is now over 7 years since I made my first buy. So why do I feel so miserable?

  • Reply to

    EMA CHMP upcoming meeting - Next week

    by grampoptemp Apr 16, 2014 10:11 PM
    grampoptemp grampoptemp Apr 17, 2014 7:58 PM Flag


    You make a good point. Most of my holdings are with large caps, with at least hundreds of millions of shares, if not billions outstanding, where one could easily pick up an occasional block of say 10,000 shares, without moving the SP more than a percent or so, if that much.

    With an 80 cent stock, a 1% move would amount to 0.08 cents, severely limiting the size of a buy to not attract attention.

    However, I was not able to find any agenda for next week's meeting, so it is entirely possible that it may be scheduled for the May or June meeting, as all we have to go by is that it will be in the 2nd quarter.

    So, there may be still time for accumulating small lots, if you happen to know at which of the 3 meetings Imagify is going to be ruled on.

  • Reply to

    EMA CHMP upcoming meeting - Next week

    by grampoptemp Apr 16, 2014 10:11 PM
    grampoptemp grampoptemp Apr 16, 2014 10:22 PM Flag


    Last chance to stock up on ACUS before the meeting next week. With virtually no interest in ACUS shares thus far, it looks like I was wrong in forecasting increased interest in ACUS shares, either pure speculation, or some sort of advance tipoff that someone knows something positive about the chance for approval of Imagify.

    Having waited this long, I am prepared to write this speculation off next week, or join in the celebration if it is approved for the intended use.

    Good luck to all.

  • 22/04/2014 - 25/04/2014 : CHMP

    Committee for Medicinal Products for Human Use (CHMP): 22-25 April 2014

    The Committee for Medicinal Products for Human Use (CHMP) is the committee that is responsible for preparing the Agency's opinions on all questions concerning human medicines.

  • Reply to

    Radiologists and Cataracts

    by agonzob Apr 2, 2014 7:12 PM
    grampoptemp grampoptemp Apr 4, 2014 8:12 PM Flag

    Hi, Agonzob;
    You make an interesting point concerning what factors should be taken into consideration in determining approval of Imagify, as well as for any other drug that may have coincident risk to the patient or the doctor.

    For one thing, obviously, the radiologist, as well as the patient benefit by avoiding the exposure, making it a no-brainer approval.

    But if it is a benefit to radiologists while it carries with it the risks of undesirable side affects for the patients, it may not be approved, depending on the potential risk, as the patient's risk vs benefit equation takes precedence.
    Therefore, impact on radiologists is an incidental benefit that should not be put before the health of the paying public.

    Sentiment: Strong Buy

  • Reply to

    Radiologists and Cataracts

    by agonzob Apr 2, 2014 7:12 PM
    grampoptemp grampoptemp Apr 4, 2014 3:25 PM Flag


    While I agree with your laudable sentiments concerning the health and eyesight of radiologists, this is hardly a reason for either approval of Imagify, or for investing in it.

    Importantly, In view of the shortness of time between now and the imminent decision, there is likely to be a flurry of speculative interest developing shortly.

    If you have waited this long, and there seems to be an excellent chance of approval, my recommendation is not to sell a single share just to maybe break even, but to wait until we have a ruling on Imagify.

    Either we strike it big, or we have a write-off.

    I'm holding out for striking it big, rather than getting even.

    Sentiment: Strong Buy

  • grampoptemp grampoptemp Mar 24, 2014 9:01 PM Flag

    going long calls on HLF is a perfect vehicle to take advantage of the tremendous leverage, should this short squeeze run the price up a multiple or two.

  • That is actually a very descriptive term that fully describes him.

  • grampoptemp grampoptemp Mar 24, 2014 8:48 PM Flag

    WARNING! While I am still highly bullish on HLF's prospects, I have resisted the temptation to buy more shares due to the possibility that the FTC rules against HLF.

    A wiser strategy would be to buy out of the money calls, January 2015 expiration. Buy one for each 100 shares you were thinking of buying. This should provide enough time for the FTC to complete their investigation. This will limit your potential loss should the FTC find HLF to be a pyramid scheme, to the cost of the premiums on the options, and not for the cost of the underlying shares.

    The higher the calls are out of the money, the lower the cost and potential loss.

    Even if the stock doesn't hit the strike price, your options can be sold at a profit if the stock moves up as speculation increases as the investigation nears completion.

    Sentiment: Strong Buy

  • Aside from whether or not the FTC will rule for or against HLF, let us all be aware that the Supreme Court's "Citizen's United" decision permitting virtually unlimited Campaign financing, is responsible for legalizing the "investing" in election campaigns by special interests.

    Consequently, elected officials who largely owe their election to massive inflows of campaign contributions become susceptible to lobbying efforts in the behalf of these "investors".

    The result is these special interests can "persuade" the elected officials they supported to use their power, access to influence and public office, to support certain interests not in the public's interest.

    This is just another unforeseen outcome of allowing special interests to influence the election of their hand-picked candidate.

    Until "Citizen's United" is repealed, the situation will likely be repeated again and again, to aid investment titans to have their way with government agencies.

    Sentiment: Strong Buy

  • grampoptemp grampoptemp Mar 14, 2014 8:12 AM Flag


    Regarding your speculation that Icahn and Ackman may have a deal is really taking the absurd to the lilmit. From what I know, these two Titans of finance hate each other's guts. It suggests that Icahn is willing to offer a lowball price for the company, just to bail out Ackman, when he's already got him in a short squeeze from which their is no exit except to take a billion dollar loss. When this is all over, Icahn may very well own HLF, and Ackman will have gone bust covering his shorts.

    With this latest FTC investigation of HLF, most investors will not touch HLF at almost any price. The shorts will have a field day, running the short position to 50% or so of outstanding shares, Then the buyback begins, driving prices up, increasing per share earnings, lowering the P/E and forcing shorts to cover well before the FTC completes their investigation.

    My recommendation is to do nothing until the next short position comes out, showing a significant increase in shares shorted, at which time it is probably best to buy out of the money calls, limiting lyour potential loss should the FTC actually find good reason to shut HLF down, and sit back and watch the fireworks and rollercoaster ride as Icahn bankf\rupts Ackman.

    Sentiment: Strong Buy

  • grampoptemp grampoptemp Mar 13, 2014 4:28 PM Flag


    Great observations.

    Consider these thoughts:

    1) With the FTC investigation, there's a 99.9% certainty that they will clear HLF of any wrongdoing.

    2) during this time, shorts will be emboldened to add to their positions, increasing the number of shares probably back to the 30 million range.

    3) This will permit HLF to buy back a much larger number of shares at greatly depressed prices, greatly increasing the per share earnings by next quarter, and thereby lowering the P/E ratio, while permitting further dividend increases than otherwise.

    4) When the FTC finally completes their investigation, they will undoubtedly clear HLF of wrongdoing, thereby touching off a major short squeeze, which should easily drive this stock to over $100 per share before the squeeze is over.

    I have some 40 years of experience in this marketplace, and have made some great picks, as well as some really bad ones. But my greatest killing was with Andrea Electronics (ANDR), from about 1992 to 2000 or so, which went from a split adjusted value of about $2.00 to about $30.00 before the squeeze ended. For me, that was around a 15-bagger.

    HLF is shaping up to be at least as profitable by the time this squeeze ends.

    Sentiment: Strong Buy

  • Its about time the FTC did what the taxpayers are paying them for.

    We all know perfectly well that the FTC will find little if any wrongdoing to justify Ackman's assault on a highly successful business that is marketing beneficial products.

    We've been there before with a number of other multi-level marketing businesses, and not one has ever been found to be operating illegally.

    I discusse3d this with my advisor, and he advises to hold on, not to buy more or sell out, as there is still risk in this stock, and Ackman may not be out of ammunition yet.

    As to the short position, it has gone up another 2 million shares compared to the previous number, so the shorts are apparently expecting more moves from Ackman.

    Sentiment: Strong Buy

  • Reply to

    Website now says Q2 2014

    by thebrames Feb 11, 2014 12:06 AM
    grampoptemp grampoptemp Feb 16, 2014 3:29 PM Flag

    ag, Yes, you are 100% correct. Not too long ago it was updated to show Q1 2014 in 2 entries on the website, which corrected an inconsistency where one location showed Q4 2013 and the other showed Q1 2014

  • grampoptemp grampoptemp Feb 10, 2014 7:54 PM Flag


    Thanks for the update. Sounds actually encouraging, as a request for additional information means they are making sure they get a clear picture of the advantages and risks of the Imagify process, versus the existing usage of radioactive material and x-ray process. Both of these are well known and pose serious long-term risks, and if it can be avoided, it is a far less dangerous way to look at cardiac arteries.

    As I mentioned, in the past I have had two angiograms performed, thankfully with negative results, and I know the risks of this doubly invasive procedure, involving extensive X-Ray exposure, radioactive contrast agent and insertion of a catheter into the arterial system. The only benefit is that should a stent be required, it can be done at the same time.

    I am optimistic that, when finally decided, it will be in favor of Imagify, possibly with certain specified contraindications in certain patients.

    I maintain my "Strong Buy" outlook, but with caution on getting in too deep.

    Sentiment: Strong Buy

  • grampoptemp grampoptemp Feb 3, 2014 10:39 PM Flag

    Sorry, I mistakenly wrote Ackman, rather than Icahn to bet the farm on.

  • grampoptemp grampoptemp Feb 3, 2014 10:37 PM Flag

    Bill, don't underestimate the value of having an Icahn on the team. This deal has been undoubtedly concocted by Carl, specifically to bury Mr. Ackman. Be prepared for more financial prestidigitation, all designed to bring him to his financial knees and beg for mercy. No matter what he says, he is locked into a losing position, holding all the wrong cards. Nobody likes a short-seller, especially one who has failed to pull his short attack off, and instead, gets caught with his shorts in a twist. Thus, there will be no mercy. This will go down in the history books as one of the greatest short squeezes to ever have been made possible by the short seller's own greed and mistakes.

    At this point, my long-term sentiment is "Bet the Farm" on HLF and Ackman. IMHO, You can't go wrong.

    Sentiment: Strong Buy

  • Reply to

    Shout out to steve.higgins16

    by agonzob Jan 30, 2014 5:07 PM
    grampoptemp grampoptemp Jan 30, 2014 6:26 PM Flag

    Charts and Technical Analysis is really beginning to paint a rosy picture, but, as I have warned, the dollars being used to paint this picture are chicken feed, as almost any small group could be setting us up for a dump. The only thing missing is the hype, which you would think would accompany the increase in trading activity and share price. This is an encouraging thought. It is rare that a pump and dump relies only on price increases to attract suckers.

    So, it is still more likely that what's driving this is the gambling mentality, not any insider involvement or pump and dump scheme.

    As such, I maintain my strong buy sentiment, with the proviso that this could quite possibly all end in a negative finding, and then we can wallpaper our walls with the stock certificates.

    Sentiment: Strong Buy

  • grampoptemp grampoptemp Jan 28, 2014 6:17 PM Flag

    Mr. Icahn's uncharacteristic silence? Smart man. He knows when he holds a winning hand. My bet, he is adding more shares at these prices, and will be selling to Post at around $100.00.

    Due to my somewhat excessive position in HLF, I am refraining from adding any more shares at this point, because Mr. Ackman may have a few more "aceholes" up his sleeve yet to play, and the shorts may be successful in dislodging some weak hands holding this stock. THAT will be the time to load up.

    Sentiment: Strong Buy

0.7501-0.1199(-13.78%)Apr 23 12:44 PMEDT

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