We still have biospeculators inside view of oppenheimers 17PT , the fact that analysts hate to be wrong on their assesments, is a big plus and reassuring in my eyes.
In some of trial descriptions they refer to sage 547 as an allopregnanolone solution, the trial reports have not mentioned the chemical name of sage547 ( only refer to it as an allopregnanolone solution).
Not to be controversial , but allopregnanolone is closer in chemical composition to sage drug. Ganax is a derivative but if ganax was effective why not use this in an adult study. Google sage 547 and it comes up alloprenanolone.
Hello Eduardo, i enjoy reading your occassional posts , very calming and enjoyable, thank you. My horizon is 5 years and have been holding a good amount (slightly less than half of yours). Purchased some as u did 2 yrs ago!
You seriously feel feds will state no more rate hikes??? You obviously haven't been listening to their rhetoric. They will have a watch and see attitude on economy going forward.
I should have been more specific,"will it reach the receptor" will the drug have permanency and long lasting effectiveness because the body tends to break down drugs and become less effective with time.
a steroid, has shown benefit for children;after stopping barbiturate type drugs (used to treat satus elipticus) children will begin having seizures as the prior drugs leave the body. Sage drug helps to ease these seizures but long term use of Allopregnanalone has been shown to exacerbate alzheimers. So their drug in IV form seems to have a very specific and short term use. If our drug can be utilized by the body(absorbed and reach the gaba receptors) we will have a winner. We all know this, I was doing research on why sage has such a high SP and ours is 6. The theory behind galaxolone seems right on but will it reach the receptors is the big question!!
Aricept showed a mmse score improvement of .8 to 1.3 (after yr1 ) not significant at 3yrs and the latest avxl redult showed a 2 improvement ( 23-30 is normal range under is impaired). If avxl can show continued improvement after 1 yr this will be the new standard Tx and better. Some stated the bar is low I concur!
Thanks for your response. Yes a bit more time today than usual and my position is in the mid 7's also. Nice little rebound here (probably shouldn't have said that) lol
Interesting find. (300,00 shares point 72). Not that many , wonder how many they held for tha icpt run? I played icpt from 200- 300 8 months ago. Would love a run to 70!