The BBC is reporting that tests show a protein called RBM3, involved in hibernation, may hold the key to regenerating synapses. In the early stages of Alzheimer's, and other neurodegenerative disorders, synapses are lost. This inevitably progresses to whole brain cells dying. But during hibernation, 20-30% of the connections in the brain — synapses — are culled as the body preserves resources over winter, and are reformed in the spring, with no loss of memory. Memories can be restored after hibernation as only the receiving end of the synapse shuts down. In a further set of tests, the team showed the brain cell deaths from prion disease and Alzheimer's could be prevented by artificially boosting RBM3 levels. Prof Mallucci was asked if memories could be restored in people if their synapses could be restored: "Absolutely, because a lot of memory decline is correlated with synapse loss, which is the early stage of dementia, so you might get back some of the synapse you've lost."
Thanks rkf302 -- Anyone that's invested in and believes Prana is onto real cures for AD, HD, etc. should be very interested in how we will be able to take advantage of those cures on a TIMELY basis .... NOT after it's already too late. I see the parallel with statins drawn all the time and I think that's a good analogy to PBT2.
This sounds like the kind of diagnostic tool that would let doctors "cut off AD at the pass......"
...... an interdisciplinary team of Northwestern University scientists and engineers has developed a noninvasive MRI approach that can detect the disease in a living animal. And it can do so at the earliest stages of the disease, well before typical Alzheimer’s symptoms appear. [article in Nature Nanotechnology]