Significant Clinical Findings on ALS Patient Treated with BrainStorm's NurOwn Featured in “Muscle and Nerve”
BrainStorm Cell Therapeutics Inc. 38 minutes ago
NEW YORK & PETACH TIKVAH, Israel--(BUSINESS WIRE)--
BrainStorm Cell Therapeutics Inc. (BCLI), a leading developer of adult stem cell technologies for neurodegenerative diseases, today announced the upcoming publication of a case report on an individual patient treated with the company’s NurOwn™ cell therapy in "Muscle & Nerve" (John Wiley & Sons). The report, which looked at one patient diagnosed with both Myasthenia Gravis (MG) and Amyotrophic Lateral Sclerosis (ALS) showed significant improvements in both cognitive and motor function following initial and repeat treatments with NurOwn.
The paper, entitled "Rare Combination of Myasthenia and ALS, Responsive to MSC-NTF Stem Cell Therapy" by Professors D. Karussis, Z. Argov, O. Abramsky and their colleagues at Hadassah University Medical Center in Jerusalem, as well as Professor V. A. Lennon from Mayo Clinic in Rochester MN, describes the rare case of a 75-year old man diagnosed with MG and ALS who was treated with NurOwn cells on a compassionate basis. One month after receiving both intrathecal and intramuscular injections of the cells, the patient demonstrated significant improvement in cognition, speech, and muscle power. Initial therapy led to improvement in the ALS Functional Rating Scale (ALSFRS-R), respiratory forced vital capacity (FVC) and cognitive function. Following therapy, the patient’s ability to speak improved from dysarthria to being able to deliver a speech clearly to an audience.
At 6 months post-transplantation, due to progression of weakness and deterioration in cognition, a repeat injection of Brainstorm's NurOwn, was performed. Again, improvements in ALSFRS-R and respiratory forced vital capacity (FVC) were observed following second treatment. Treatment with Nu
The trial is now over. So there is no more blind as that was a conditional of the trial protocol. they can continue to follow those that remain to obtain more information, but there is no more "trial" and therefore no further blind.