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Celsion Corp. Message Board

hjsdmi 12 posts  |  Last Activity: 1 hour 53 minutes ago Member since: Oct 16, 2000
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  • hjsdmi by hjsdmi 1 hour 53 minutes ago Flag

    The FDA's new "breakthrough" product designation allows new drugs to win approval after just a single round of testing, instead of the usual three. -----"A breakthrough drug is one that may offer important new benefits for patients with serious or life-threatening disease who are especially in need of new safe and effective treatments," said Janet Woodcock, director of FDA's Center for Drug Evaluation and Research.
    And,, if the agency is seeing promise in trial results,, they can ask the trial sponsor to apply for BTD..

    jat,,,

    Sentiment: Buy

  • If the agency likes trial results "they" can suggest the drug company submit for BTD,, even phase 1 results..
    DO YOUR OWN SEARCH...

    jat,,,

    Sentiment: Buy

  • hjsdmi hjsdmi Jun 23, 2014 12:34 AM Flag

    Story is based on materials provided by University of Southern California.

    In the first evidence of a natural intervention triggering stem cell-based regeneration of an organ or system, a study at USC shows that cycles of prolonged fasting not only protect against immune system damage -- a major side effect of chemotherapy -- but also induce immune system regeneration, shifting stem cells from a dormant state to a state of self-renewal.

    In both mice and a Phase 1 human clinical trial, long periods of not eating significantly lowered white blood cell counts. In mice, fasting cycles then "flipped a regenerative switch": changing the signaling pathways for hematopoietic stem cells, which are responsible for the generation of blood and immune systems, the research showed.

    The study has major implications for healthier aging, in which immune system decline contributes to increased susceptibility to disease as we age. By outlining how prolonged fasting cycles -- periods of no food for two to four days at a time over the course of six months -- kill older and damaged immune cells and generate new ones, the research also has implications for chemotherapy tolerance and for those with a wide range of immune system deficiencies, including autoimmunity disorders.

    "We could not predict that prolonged fasting would have such a remarkable effect in promoting stem cell-based regeneration of the hematopoietic system," said corresponding author Valter Longo, the Edna M. Jones Professor of Gerontology and the Biological Sciences at the USC Davis School of Gerontology, and director of the USC Longevity Institute.

    Sentiment: Buy

  • Reply to

    The importance of MRI data for NSI-189

    by nate_m98 Jun 21, 2014 11:29 AM
    hjsdmi hjsdmi Jun 21, 2014 8:59 PM Flag

    no2,, a ? ,,, is it not just as important to know that the hippocampus stopped growing when nsi189 was stopped.. Don't need any more fatheads to care for...

    jat,,,

    Sentiment: Buy

  • Reply to

    HIFU, RCW, and Optima

    by dogledon Jun 17, 2014 8:29 AM
    hjsdmi hjsdmi Jun 19, 2014 8:21 PM Flag

    SEARCH FDA + BTD !!!

    Sentiment: Buy

  • Reply to

    HIFU, RCW, and Optima

    by dogledon Jun 17, 2014 8:29 AM
    hjsdmi hjsdmi Jun 18, 2014 11:10 PM Flag

    Also consider;; RCW treatment should be eligible for BTD ,, especially if P2 improves efficacy over P1...

    just-a-thought,,,

    Sentiment: Buy

  • Reply to

    Fibbonacci1170 on twitter

    by velopismo Jun 7, 2014 7:05 PM
    hjsdmi hjsdmi Jun 8, 2014 1:40 PM Flag

    Very doubtful Fib-er knows anything about 189-1b results..
    Trial information:
    Title: A Phase Ib Randomized, Double-Blind, Placebo-Controlled, Multiple-Dose Escalation Study Evaluating the Effects of NSI-189 Phosphate, A Neurogenic Compound, in Patients with Major Depressive Disorder (MDD) -------------- meaning the caregiver & patient don't even know who is getting what !!!

    Must be the front half of FIBBER-MAGIEE & MOLLY...

    jat,,,

    Sentiment: Buy

  • Reply to

    "This is extremely robust Phase 1b data."

    by jepasto1 May 27, 2014 8:24 AM
    hjsdmi hjsdmi May 27, 2014 9:10 AM Flag

    ************* REPEATS ========
    Definition of ROBUST,,, strong and healthy. : strongly formed or built. : successful or impressive and not likely to fail or weaken.
    AND;;
    Fava is the first author of the abstract, and he is as highly credentialed and respected in his specialty as you can get !!!

    Hmmmmmm,,, jat,,,

    Sentiment: Buy

  • Reply to

    SOUNDS FAMILIAR ;

    by hjsdmi May 19, 2014 2:35 PM
    hjsdmi hjsdmi May 20, 2014 3:39 PM Flag

    lady143 ,,, I tried to post that story also but yahoo would not allow it.. And with a suggestion--question.. Will CUR start storage facilities so people can freeze their own cells for their own future treatments,, using CUR's technology to expand the cells when needed ..

    O-well ,,,,,, jst,,,

    Sentiment: Buy

  • Reply to

    SOUNDS FAMILIAR ;

    by hjsdmi May 19, 2014 2:35 PM
    hjsdmi hjsdmi May 20, 2014 11:58 AM Flag

    ranter -- the post was for FYI only,, sorry!!

    And,, you sound female,, in the middle of your monthly..

    Hmmmm,,,

    Sentiment: Buy

  • SALT LAKE CITY – Researchers at the University of Utah are working to help people who suffer from multiple sclerosis, and so far their work has promising results among mice.

    Researchers are using stem cells to treat mice with a condition similar to MS, and some mice were able to walk just days after treated.

    Dr. Peter Jensen, a professor at the University of Utah, chairman of the Department of Pathology, spoke about the findings.

    “Remarkably, animals that were paralyzed, could walk,” he said.“Which was a complete surprise to us.

    Dr. Tom Lane, another professor of pathology involved in the project, said the results weren’t what they expected. Lane made the discovery after injecting human stem cells into the spinal cords of the mice. He said he was hoping to discover why the immune systems of mice often reject human stem cells, but what he found was that the stem cells were repairing the damaged nerves in the disabled mice.

    “In essence, you’re regenerating the function of damaged nerves and gives hope for a potential therapy down the road.

    “What we hope to do is to find out what these cells are secreting that actually change the environment within the diseased tissue, and if we can identify what factor or factors are being secreted, then we could potentially make this drugable so that it could be injected into people that have MS, or the long term goal would be to make it into a pill form so they could take it orally,” Lane said.

    Jensen said the research could have applications in treating a variety of issues. forms of dementia, as well as Parkinson’s and diseases that have traumatic injury to the brain or spinal cord,” he said.

    Hmmmmm,,,

    Sentiment: Buy

  • Google NYT + Young Blood May Hold Key to Reversing Aging

    jat,,,

    Sentiment: Hold

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