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Amarin Corporation plc Message Board

intrinsic5000 1380 posts  |  Last Activity: Nov 17, 2013 8:33 PM Member since: Apr 22, 2008
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  • intrinsic5000 by intrinsic5000 Nov 17, 2013 8:33 PM Flag

    why this tanked in Oct? Was it the AF piece or something else?
    And what makes you think that the other drug in their pipeline -CPP-115 will yield positive results?

    Thanks

  • intrinsic5000 intrinsic5000 Sep 14, 2013 9:21 PM Flag

    Mine too!!!!!!

  • Reply to

    Seemingly, AH Has Been Settled

    by frankposting Jul 8, 2013 5:58 PM
    intrinsic5000 intrinsic5000 Jul 8, 2013 6:13 PM Flag

    swalche--what are your thoughts on the timing of the secondary.

  • intrinsic5000 by intrinsic5000 Jul 8, 2013 6:05 PM Flag

    Totally ridiculous! Forst he should have shut his mouth about the buyout scenario and clearly if he was considering funding this GIA, he should have diluted the shares last yr. What is worrisome is that doing a secondary at this moment in time means that there is no buyout or partnership that is taking place--Am I wrong? Give me your viewpoint something more than #$%$ off that comes from Todhale!

  • Reply to

    Lets put some educated guesses out there

    by intrinsic5000 Jul 5, 2013 4:10 PM
    intrinsic5000 intrinsic5000 Jul 5, 2013 5:47 PM Flag

    The one good thing though is that I have reached Log term status--but of couse there is NO capital gain!

  • Reply to

    Lets put some educated guesses out there

    by intrinsic5000 Jul 5, 2013 4:10 PM
    intrinsic5000 intrinsic5000 Jul 5, 2013 5:21 PM Flag

    Thanks cj. Todhale--I have another word for you--would you like to know what that is?

  • Reply to

    Will we go to $15 by Dec!!!!

    by intrinsic5000 Jul 5, 2013 3:39 PM
    intrinsic5000 intrinsic5000 Jul 5, 2013 4:13 PM Flag

    NOPE!!!!!!

  • Will I EVER be able to breakeven on this investment by Jan 2014. Cost basis is in the $14s. And No I can't avg. down!

  • Reply to

    Will we go to $15 by Dec!!!!

    by intrinsic5000 Jul 5, 2013 3:39 PM
    intrinsic5000 intrinsic5000 Jul 5, 2013 4:02 PM Flag

    Its actually $14.4

  • Reply to

    Will we go to $15 by Dec!!!!

    by intrinsic5000 Jul 5, 2013 3:39 PM
    intrinsic5000 intrinsic5000 Jul 5, 2013 3:53 PM Flag

    I just want to breakeven!

  • intrinsic5000 by intrinsic5000 Jul 5, 2013 3:51 PM Flag

    far away from $15

  • intrinsic5000 by intrinsic5000 Jul 5, 2013 3:39 PM Flag

    I'm getting so exhausted!

  • intrinsic5000 by intrinsic5000 Jun 17, 2013 2:01 PM Flag

    Saw a post on ihub that said that Lerrink had a note out today--anyone care to paste it here?

  • intrinsic5000 intrinsic5000 Mar 4, 2013 3:18 PM Flag

    Hi zoo (and croesus)--

    So you really think that Anchor market will not achieve a high penetration unless the REDUCE-IT study comes out positive? If so, do you think Marine indication alone is enough to command a high premium to the stock price?

  • AMRN bulls should ask VVUS how their go it alone launch has gone so far. They're in a similar battle of discounting and coupons. There's going to be a lot of myths out there to debunk that Vascepa is not just your standard fish oil.

    To all the bulls that taught the LDL raising ability of Lovaza.... keep in mind that current guidelines suggest statin therapy to bring patients to LDL goals before being concerned about triglycerides. Once a patient is maximized to their LDL goal and the statin has had a chance to also lower the triglycerides, a triglyceride lowering agent can be considered. Fibrates remain a standard of care due to their effectiveness and now their costs. Tricor is one of the best selling fibrates to date and has now become available generically. Vascepa will have to compete with this and soon generic Lovaza.

    In a trial of Lovaza with simvastatin, patients with high triglycerides were first treated with simvastatin and optimized to their LDL targets before initiating Lovaza. After initiation of Lovaza triglycerides were decreased by ~ 30%, Apo-B ~6% and LDL DECREASED by 0.7% or 3 points from 91 to 88. This scenario follows much of the real world. Statins are the mainstay of therapy and the trial involving simvastatin shows apo-b was reduced and LDL really wasn't moved. Most studies suggest that LDL 100 may start the build of plaques within arteries. Lovaza did not move the LDL to dangerous levels at all which is the general theme I feel AMRN bulls try to suggest.

  • intrinsic5000 by intrinsic5000 Mar 1, 2013 8:55 PM Flag

    Wow...

    Did the FDA change its mind about the NDA?..Did'nt the company just file for the ANCHOR 35 million patient indication..

    The drop to pre ANCHOR levels is ridiculous..I simply had to buy when the PPS hit $7.52...

    The prinicipal argument hoisted against AMRN is skepticism that doctors are going prescribe (actually suggest) patients take fish oil instead of putting up money for the good stuff..Included in this are weak arguments that patients can receive the same benefits from fish oil as they do from Vascepa..Weak arguments because this is simply not true. The fact the company is not featuring a full court press on the sales results in the first couple of weeks is being used as a proof the drug will be a long term failure..None of these arguments will hold water..

    A problem AMRN faces, and one that is seldom stated, is that Vascepa, because it is a fish oil derivative, is not very sexy in the biotech world filled with miracle cancer cures DNDN and fancy diagnostic electronic devices like NEOP (or whatever they call it now)...Well sexy or not Vascepa will make money and plenty of it..The share price at present allows for plenty of skepticism and then some..

    AMRN's valuation is not difficult if you know how many patients they will service. The drug is administered daily in known quanity and its profits are determined in the same way you would the profits of a beverage company..Figure costs of goods and services including financing, subtract these from revenues and you have profits..At the present PPS an estimate based on drug industry averages...indicates AMRN would only have to be treating 400K patients out of a total cohort of 40 million potential patients..To reach its current valuation. This would be a conversion of 1%..This is way beyond skepticism..

    Vascepa simply put addresses a potential market that is so vast that the market has trouble getting around it. The pathophys is complex and well understood by very few investors..IMHO the rationale is very good and very important...but as an investment it does have to be that good, because the indication is so enormous...

    ": ) JL

  • Reply to

    Sales

    by golongin2008 Mar 1, 2013 3:06 PM
    intrinsic5000 intrinsic5000 Mar 1, 2013 8:02 PM Flag

    golong-

    You're getting as annoying as Alex!

    How can you extrapolate weak sales for Vascepa based on sales numbers from ONE month. If you're so pessimistic about this triglyceride therapy then just move on! You seem to doubt that Vascepa has anything to offer to patients.

    Glad the akanz bozo is off the Boards--maybe you could join him!

  • intrinsic5000 by intrinsic5000 Feb 19, 2013 3:31 PM Flag

    OMG

  • Reply to

    GSK

    by intrinsic5000 Feb 16, 2013 5:41 PM
    intrinsic5000 intrinsic5000 Feb 18, 2013 4:09 PM Flag

    One more thing. Do you think that given the lack of correlation of clinical outcome with other triglyceride lowering drugs, BP has become a bit less enthusiastci of triglyceride lowering drugs, ie Vascepa. Also--who knows if the REDUCE IT study will come up positive.

    Lovasa did close to a billion in sales, but maybe BP doesn't expect that to continue?

  • intrinsic5000 by intrinsic5000 Feb 16, 2013 5:41 PM Flag

    In my view, GSK is definitely interested, but the disagreement is the price. They probably don't anticipate a large percentage of patients with triglycerides in the 200-500 range opting for medication ie Vascepa. And moreover, as williams has repeatedly pointed out Lovaza sales already include 50% off label use, eventhough Lovaza is not approved for the Anchor indication.

AMRN
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