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American Science & Engineering Inc. Message Board

iruleyoulose 11 posts  |  Last Activity: Dec 9, 2014 7:35 PM Member since: Dec 3, 2007
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  • Reply to

    Extension trial dosing should be completing

    by brewman228 Dec 8, 2014 9:15 PM
    iruleyoulose iruleyoulose Dec 9, 2014 7:35 PM Flag

    You cannot do a partial release of the data. Lawyers can have a field day and the SEC won't look so kindly if the safety data is released and then efficacy data is later that is not favorable.

    Sentiment: Buy

  • Reply to

    Extension trial dosing should be completing

    by brewman228 Dec 8, 2014 9:15 PM
    iruleyoulose iruleyoulose Dec 9, 2014 4:46 PM Flag

    However, will be at least 3-6 months until the results are released. Analysis and V&V take a long time for the drug trials and with Prana, seems to take 25-50% longer.

    Sentiment: Buy

  • iruleyoulose iruleyoulose Nov 19, 2014 8:42 AM Flag

    All those shares you bought at $10 have made you lots of money, right? Just like when you shorting PLUG at $6? You have never been right on a single stock. Don't forget to wear that little helmet to protect yourself when you go outside, moron.

    Sentiment: Hold

  • Reply to

    anual report 2014 ( facts)

    by gyoung28105 Oct 15, 2014 5:13 AM
    iruleyoulose iruleyoulose Oct 15, 2014 7:11 AM Flag

    You do know you can find the same or similar statements in the annual reports of Pfizer, Biogen and even Apple? Every company lists out their risks in their annual report and the potential consequences to protect them from potential liability.

    Sentiment: Buy

  • Reply to

    Just to make a point!

    by goldex3 Oct 14, 2014 1:36 PM
    iruleyoulose iruleyoulose Oct 15, 2014 7:08 AM Flag

    The only thing I don't like are the morons who constantly change their names on this MB. Of course you won't post here for awhile, you are just going to get a new ID and post under it. You go through ID's as quick as you go through the guys at the truck rest stop.

    Sentiment: Buy

  • Reply to

    Thank you! Pickup 4k in shares @ 2.03

    by gyoung28105 Oct 2, 2014 11:26 AM
    iruleyoulose iruleyoulose Oct 2, 2014 12:13 PM Flag

    Have to remember that Prana gets substantial funding in the form of grants from the various Dementia organizations. Plus, they are elgible to submit for federal grants with ODA designation. They should be doing that, high approval rates for promising therapies. That would be a boost for share price as well and alleviate dilution.

    Sentiment: Buy

  • iruleyoulose iruleyoulose Oct 2, 2014 11:00 AM Flag

    Dementia has been a priority with the FDA for a while. Prana has to show substantial improvement over available therapies as indicated above. If Prana had not f'ed up the last trial, they would be on fast track status and probably submitting for approval this year, with compassionate use approved by now.

    Hopefully, the follow on studies will show the improvement. Prana still has to prove the effectiveness to the FDA's satisfaction, does not matter what we post or say. Once they do that, then the share price will be like JAZZ.

    Sentiment: Buy

  • Reply to

    Purchased 2,000 shares today

    by hjcnyc Sep 10, 2014 3:55 PM
    iruleyoulose iruleyoulose Oct 1, 2014 2:09 PM Flag

    Have any other clairvoyant stock forecasts - will option opposite.

    Sentiment: Buy

  • Reply to

    Pran 3.31.14 Failed AD drug.

    by gyoung28105 Sep 27, 2014 6:49 PM
    iruleyoulose iruleyoulose Sep 29, 2014 7:22 AM Flag

    GY, the test was reported as you state, but there were anomalies that render the testing suspect. My guess is that if Prana had done their DD and conducted peer reviews and updated the basis for the trial before conducting it, then the results would have been different. They allowed variables into the test program that in all honesty should not have been allowed for a true test.

    HD has more potential than you indicate, I think off label use would surpass the use for HD itself.

    A true and balanced analysis would indicate that the drug did not meet its efficacy goals, met its safety goals and the test was flawed. Hence, I think this helped drive Prana to bring someone like Shoulson on board.

    Another potential boost to the share price is the release of the PBT434 results at the beginning of 2015.

    Buying Prana is a high risk investment - no respectable investment advisor would say otherwise, there is potential upside and I will take the 100%+ increase over the next year. I think good progress with Phase III and positive results of PBT434 will propel the share price into the $5 - $10 range though. Good Phase III results will propel the stock price into the $20 - $40 range, just have to be patient. My mutual funds over the last month or two have taken a beating after posting a 24% yearly increase on average over the last 4 years. Market is due for a correction, so if Prana can go positive the next year, then that is fine for me.

    I have been lucky with shares like SRPT and CYTR, bought at a low price and sold higher for example several times. I a little over 2000 shares of LVS that I bought back in 2009 out of the 12000 I had bought. Lost money as well on other stocks. Invest as you see fit.

    If it fails all the trials, then the company has nothing. Investors should only invest what they can afford to lose.

    I would like to see Prana try for humanitarian use approved in the next couple of months. That would be a huge share price booster

    Sentiment: Buy

  • iruleyoulose iruleyoulose Sep 25, 2014 7:26 AM Flag

    Why do you have these feelings of inadequacy that compel you to post such idiocy? Are you trying to over compensate for some sort of inadequacy elsewhere?

    Sentiment: Buy

  • Reply to


    by jjrenaldo Sep 24, 2014 9:37 AM
    iruleyoulose iruleyoulose Sep 24, 2014 9:47 AM Flag

    Why do you feel the need to create and expend the time and effort to constantly create new ID's day after day to post on a MB?

    I think you should get a life, but, then again, the old folks doesn't leave much to do, other than waiting for your daily enema and Depends change.

    Sentiment: Buy

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