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pSivida Corp. Message Board

jdliberty02 209 posts  |  Last Activity: Nov 26, 2014 9:25 PM Member since: Jun 18, 2013
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  • Reply to

    Nice Recovery Week

    by mickmack50 Nov 26, 2014 4:55 PM
    jdliberty02 jdliberty02 Nov 26, 2014 9:25 PM Flag

    Hi Mick, Thanks. I was wondering the same thing, but then I realized sometimes the correctness of ones thoughts is the opposition they receive. Happy Thanksgiving to All, including the turkey shorts!

    Sentiment: Strong Buy

  • Reply to

    Nice Recovery Week

    by mickmack50 Nov 26, 2014 4:55 PM
    jdliberty02 jdliberty02 Nov 26, 2014 5:25 PM Flag

    Hi Mick, Here here! I share Kools observation that the current correction is substantially an adjustment to the oversold state of PSDV and ALIM. As we quickly are turning into the 1st quarter of 2015, I will be excited to see ALIM's penetration of the DME market and the revenue pipeline begin to flow for the benefit of both companies bottom line and sp. I also share Kool's observation that the upcoming conference could be the time PSDV announces some of the catalysts that the company has indicated would be forthcoming in the last of half of 2014, first part of 2015. Thanks for your morale boosting posts that have helped a lot of us small investors stay long, strong and in the black.

    Sentiment: Strong Buy

  • Reply to

    Thoughts?

    by prxl Nov 22, 2014 11:27 PM
    jdliberty02 jdliberty02 Nov 23, 2014 3:14 PM Flag

    Overlap on Psi patents?

    Sentiment: Strong Buy

  • Reply to

    Pfizer Latanoprost glaucoma

    by billygbillyg Nov 20, 2014 8:33 PM
    jdliberty02 jdliberty02 Nov 22, 2014 6:30 PM Flag

    tblew, the phase 1 tests were initiated in 2011 when PSDV renegotiated its agreement with PFE. Can you cite where Dr. Ashton advised of problems with psdv's technology and summarize what he said? Thanks

    Sentiment: Strong Buy

  • Reply to

    Glaucoma and sustained implant years away

    by terry290737 Nov 21, 2014 4:53 PM
    jdliberty02 jdliberty02 Nov 21, 2014 5:56 PM Flag

    Great post Terry! I am curious what types of glaucoma Xalatan is used to treat?

    Sentiment: Strong Buy

  • Reply to

    Pfizer Latanoprost glaucoma

    by billygbillyg Nov 20, 2014 8:33 PM
    jdliberty02 jdliberty02 Nov 21, 2014 2:35 PM Flag

    Should PFE pickup the Latanoprost program after PSDV completion of a Phase 2 and make the milestone payment for $20 million, PFE would then be responsible for conducting the Phase 3 trials and to obtain FDA approval. PSDV would then be entitled to a double digit royalties after approval. The agreement may or may not include other post Phase 2 milestones beyond the $20 million. As reflected in the PFE 2013, sales of Xalatan have declined due to loss of product exclusivity in the US in 2011 and in the EU in 2012. PFE has enjoyed a significant portion of the $1.5 Billion worldwide market for Latanoprost. An August 11, 2014 article available online by Norton Rose Fulbright discusses the patent history of Latanoprost and the 2012 Italian abuse of dominant position legal actions and fines levied against PFE. If PSDV's delivery systems can improve the efficiacy and reduce the side effects of latanoprost and at the same time reestablish PFE proprietary dominance, it would be difficult to understand why they would not be proceeding post haste with the partnership with PSDV.

    Sentiment: Strong Buy

  • Reply to

    Pfizer Latanoprost glaucoma

    by billygbillyg Nov 20, 2014 8:33 PM
    jdliberty02 jdliberty02 Nov 21, 2014 12:10 PM Flag

    The Generic Latanoprost patent expired in 2011. PSDV is responsible for its Latanoprost program through Phase 2 under an agreement with PFE. After completion of the Phase 2, PFE has the option to pick up and fund the program for a $20 million milestone payment. Mick's assessment of Dr. Ashton's CC comments seems correct. With Dr. Ashton's past history of successful and constructive negotiation, who knows what type of re-negotiation or partnership may be in play.

    Sentiment: Strong Buy

  • Reply to

    Pfizer Latanoprost glaucoma

    by billygbillyg Nov 20, 2014 8:33 PM
    jdliberty02 jdliberty02 Nov 20, 2014 8:56 PM Flag

    It is my understanding that Latanoprost is on the back burner at this time.

    Sentiment: Strong Buy

  • Reply to

    Similarities of Silicon & Carbon

    by jdliberty02 Nov 19, 2014 12:11 AM
    jdliberty02 jdliberty02 Nov 19, 2014 3:30 PM Flag

    Do the PSDV patents include and employ the use of silica "PSiO2" nanoparticles as well as silcon "PSi"?

    Sentiment: Strong Buy

  • Reply to

    Similarities of Silicon & Carbon

    by jdliberty02 Nov 19, 2014 12:11 AM
    jdliberty02 jdliberty02 Nov 19, 2014 2:59 PM Flag

    Thanks Alyn, distinction well taken. From wisegeek, "Although it may appear that the words silicon and silicone can be used interchangeably, there are some significant differences between them. Silicon is a natural chemical element found in great abundance on Earth, primarily as a major component of common sand. Silicon is generally found in a crystalline form. Silicone is a man-made substance derived from silicon and other chemicals, and it may be a liquid or a rubber-like plastic polymer."

    Sentiment: Strong Buy

  • Reply to

    Similarities of Silicon & Carbon

    by jdliberty02 Nov 19, 2014 12:11 AM
    jdliberty02 jdliberty02 Nov 19, 2014 12:44 PM Flag

    Medical grade silicone is also tested for biocompatibility, which means that it is compatible with the human body and not reactive with body fluids and tissue. The FDA regulates medical silicone that is implantable in the body. There are three categories of medical silicone, non-implantable, short-term implantable and long term implantable. When you consider the wide range of medical silicone products it provides better insight into the quality of production for medical silicone when it is implanted into the body. Medical silicone is used for medical tubing, which is part of air, fluid and medicine delivery into the body. It is also used for fluid transfer out of the body, including dialysis and catheters. Medical silicone devices are also used for pain pumps, blood pumps, insulin pumps, anesthesia breathing materials and devices, oxygen supply systems, IV systems, blood separation systems, ultrasound equipment and more. Implantable medical devices include pacemakers, artificial joints and urological implants for vascular repair in the urinary tract. Silicone is also used for surgical sutures and scar reducing bandages and creams. Recent advances in neurostimulation and neuromodulation are being developed to treat Parkinson’s, epilepsy, migraine and spinal cord injury.

    Sentiment: Strong Buy

  • On 10-31-14 the short data showed short interest of 876,789 shares on average volume of 155,216 shares and 5.64 days to cover. Todays volume 37,915. I am learning here. If volume is relatively low won't that drive up the number of days to cover and create substantial risk to short players?

    Sentiment: Strong Buy

  • Terry and others have talked about the futuristic applications of biosilicon delivery systems that also integrated silicon for data and wireless processing. Below is a short article discussing silicon and carbon (human beings are 18% carbon)

    From Ehow article by Chuck Robert: Silicon and carbon are among the most similar elements on the periodic table. They have some major differences, such as silicon being an inorganic compound, but many of the compounds created using carbon or silicon are almost twins. Carbon is the element of life forms, playing a major role in metabolic processes, while silicon is an element of the machines, serving as a major component for parts, such as semiconductors.

    A large portion of the Earth is comprised of silicon and carbon, making them among the most significant nonmetallic substances. Both silicon and carbon are abundant throughout the universe and on the planet Earth.

    Both carbon and silicon commonly form compounds, easily sharing electrons with other elements. Carbon will make multiple bonds with other carbon molecules by forming single, double and triple covalent bonds. Carbon forms compounds such as methane, propane, butane, benzene and carbon dioxide. Silicon forms compounds such as silane, disilicon hexahydride, silicon tetrafluoride and silicon tetrachloride. Carbon and silicon are often combined, with carbon serving as silicon's backbone. However, silicon can also form silicon polymers, which are silicon and oxygen structures.

    From a wikipedia article, "some elements that are clearly used in lower organisms and plants [silicon] are probably needed by mammals also, but in far smaller doses.

  • Reply to

    My Hopes

    by flexed1962 Nov 13, 2014 3:59 PM
    jdliberty02 jdliberty02 Nov 18, 2014 6:58 PM Flag

    Looks like it may be a bigger Yahoo issue. I had some important emails sent through yahoo never show up....What the #$@#@%%

    Sentiment: Strong Buy

  • Reply to

    My Hopes

    by flexed1962 Nov 13, 2014 3:59 PM
    jdliberty02 jdliberty02 Nov 18, 2014 4:30 PM Flag

    I think PSDV management has been extremely cautious in not overstating its circumstances. I honestly believe that time will show PSDV management to have kept its eye on the ball in bringing a home run to its investors. The information that has been released thus far supports biosilicon, Durasert and Tethadur delivery systems as having great promise. I donu0027t get the doom and gloom. Good things take time. Have patience. Delivery systems such as Tethadur are one of the 21st century medical frontiers and Tethadur may be one of the most successful.

    Sentiment: Strong Buy

  • jdliberty02 jdliberty02 Nov 16, 2014 11:41 PM Flag

    Perhaps are related company to the BlackRock PSDV institutional investors paid the next largest sanction.
    "BlackRock Institutional Trust Company – The California-based firm agreed to pay disgorgement of $1,122,400, prejudgment interest of $22,471.13, and a penalty of $530,479."

    Sentiment: Strong Buy

  • jdliberty02 jdliberty02 Nov 16, 2014 9:57 PM Flag

    Stock price dropped from the March 2014, 4.11 RA acquisition cost to a low of 3.40 on May 13th. Can't say I understand how or if this shows any manipulation with regard to PSDV. The fact that the funds were used to promote the development of Tethadur and Medidur suggests they saw the potential.

    Sentiment: Strong Buy

  • WATERTOWN, Mass.--(BUSINESS WIRE)-- pSivida Corp. (NASDAQ:PSDV) (ASX:PVA), a leader in developing sustained release, drug delivery products for treatment of back-of-the-eye diseases, announced today that RA Capital has entered into a securities purchase agreement with the Company to invest approximately $7.0 million in a registered direct offering through the sale of a total of 1.7 million shares of the Company's common stock at a per share price of $4.11.

    The offering is expected to close on or about March 18, 2014 subject to the satisfaction of customary closing conditions. The Company intends to use the proceeds from this offering to accelerate its Tethadur program, fund its clinical trials for posterior uveitis and for general corporate purposes.

    Sentiment: Strong Buy

  • jdliberty02 jdliberty02 Nov 16, 2014 9:22 PM Flag

    Review of the SEC press release identifies that RA Capital suffered the greatest sanction of $3.5 million compared to an average sanction substantially below $100,000.

    Sentiment: Strong Buy

  • jdliberty02 jdliberty02 Nov 16, 2014 8:35 PM Flag

    So, was the sell off part of a settlment in some way compelled by the SEC, just a way to raise cash to pay the disgorgement and penalties of ~$3.5 million or ????, I understand that over the years RA Capital has bought in and sold out of PSDV

    Sentiment: Strong Buy

PSDV
4.39+0.13(+3.05%)Nov 26 4:00 PMEST

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