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Amarin Corporation plc Message Board

jesse.livermore 1 post  |  Last Activity: Dec 5, 2014 11:38 AM Member since: Aug 21, 2009
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  • jesse.livermore jesse.livermore Dec 5, 2014 11:38 AM Flag

    Chen...Can I speculate on the fact you are probably not a math major. FYI, its not 62 out 18,000 (18,645) patients . Half of these guys were not taking EPA. So lets say 62 out of 9,000. So what does this mean. To begin with in the whole 18,000 plus patients there were only 586 'events" . That puts a cap on the number of cases EPA can save in this study. 62 saves out of 600 events in a group divided in two means 20% reduction , or roughly one out of five...That's pretty impressive. extrapolatedf to 90 million at risk patients in the USA this comes out to 620, 000 saves.

    Now about the agina vs death argument. First of all for all you non MD medical experts, chest pain does not mean it's angina. When as one of you mentioned a patient goes to the ER for chest pain this could range from costo chondritis, to heart burn, disecting aneurism, angina or MI and several other diagnosis. Angina is accompanied with EKG changes. Angina means you have coronary disease and documented angina is a valid criteria for assigning a patient to the secondary intervention group. Wait till one of you boo birds gets your first angina attack and see how you like it.

    The reality in JELIS was that EPA lowered risk categories major and minor a similar amount on a percentage bases. That was roughy 20% accross the board., from sudden death on down. Angina just happens to be the most frequent event. Also JELIS's critics were looking to disparage JELIS and made a series of statements that were questionable.

    ": ) JL

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