Lil'Kim you need to get some tutoring so that you will be able to read. I've named the two that ISIS has. Tell me how much money vicl has brought in with regards to milestone payments over the last three years besides that $4 million that they brought about a week ago. ISIS has made over $175 million so far this year if you count the BIIB milestone payments, GSK, the deal with Bayer, and the selling of some of their RGLS. The longer you keep on posting the same thing with superficial information, nothing new, and no awaremenss in regards to new scientific advancements iat ISIS the more inconsequentail you will become. I'm trying to look out for you Chums. I've given you info on ISIS and reasons why you should selll vicl. You are all excellent sea captains and you will alll go down with the good ship vicl. Thank you again for all you do to channel the energy that allows the reverse VOO-DOO curse to take place. t
The Chums are relentless but here is a summary of the info you will get from them with a lot of denial and ignorance:
1)The article in Worth Magazine mentioned both ISIS and vicl in 1989. Since that time they keep hitting on no drug in 27 years. ISIS has two drugs out and both, even though not spectacular are better than anything vicl has out.
2)They refuse to recognize that vicl's share price is much lower now than what it was in 1898 and come up with convoluted ways to try and make vicl look like it's share price has beaten ISIS.
3)After 27 years vicl has a puny pipeline and it does not seem to be growing at all. Moreover other vaccine companines are pounding it with their newer and better technology.
4)The company has no real blockbuster potential drugs and their latest one which is wanting to decrease viral shedding by a lowly 30% seems to be able to be usurped by almost any antiviral that has effects on this virus. In ohter words they are going for very low hanging fruit and will have tremendous competition with better competitors in the very near future.
5)We all owe the Chums a big thanks for two reasons. They have shown people who have taken the time to llook at all of the issues how far off they are and how shallow their arguments are. And number two they have helped create a lot of wealth for shareholders with their reverse VOO-DOO curse on ISIS....if only they could patent that, kind of like an Indian rain dance. t
This maximum tolerated dosing is truly amazing. If the drugs are as effective as they seem now I'd rather own this kind of franchise and have to myself than to be like big pharma and be competing all for the same targets once someone comes up with a good idea like the PD-1's. MRK, BYM, and who knows who lese are all going to be piling into this area. Same thing with the CAR--T's as well. t
IMO the only real short temr advancement for this population would be with stem cells that get piggy-backed onto the heart and differentiate into myocytes. There has been mixed literature on this as well. I do think that MSTX is onto something in that they have a protective coating that goes around the disrupted cedlls that allows the cells to repair themselves. it isn't a cure but the data looks good and Beaumont Hosp in Detroit is conducting a lot of the studies. t
Pretty amazing bicp in regards to the MTD'ing. The other thing that gets my attention is the multiple orphan drug indications for Archexin:
Archexin is a potential best-in-class, potent inhibitor of the protein kinase phosphorylated Akt-1, which is over-expressed in cancer cells and which we believe plays a critical role in cancer cell proliferation, survival, angiogenesis, metastasis and drug resistance. Archexin has received "orphan drug" designation from the FDA, for RCC, glioblastoma, ovarian cancer, stomach cancer and pancreatic cancer. That designation provides tax incentives for clinical research and a waiver of user fees. In addition, a drug that is approved for its orphan-designated use receives seven years of exclusivity after approval, during which the FDA generally cannot approve another product with the same active moiety for the same indication.
Lil'Kim doesn't it seem suspicious to you that ISIS has SIX major pharmas in major deals with them and vicl got a pxx-pxx sandwich a7-eleven store with the anti fungal drug that they bought? t
fred, Once you chums get into commune you guys should call it the Flintsone Commune based on your antiquated keepsake vicl. Mr. T would say about you guys, "I pity the fool(s).". t
vicl will stay a baby and the baby suffers from failure to thrive. t
I've always said that OGXI was an extrmely risky stock in that they were woringing with older ISIS technology. They don't have access to the newer technology from ISIS the game-changer technology. As for vicl there has not been any advancement on regards to new generation technology and competitors have really surpassed them in technology. That will become more clear to you over the next two years and you'll have to change your name after you start singing that song "Achy-Brachy Heart" over and over again. That will be called complex echolalia.....maybe vicl can get vaccine for that. Denial, ignorance, and jealous is no way to go through life son. t
Lil'Kim you are still in denial about your vicl situation. They announced their earnings today. They lost a penny less than expected. They didn't even gross more than $5 million. The more you stay angry the more you will get more angry. A viscous cycle for you and the Chums. That will eventually be even better for ISIS investors as the VOO-DOO reverse curse will pick up more energy. Thank you for all you do too Lil'Kim.....I've always thought you were innocent of those crimes you were charged with too. Prepare for your spankings and they won't hurt as much and stay true to yourself.......as long as you can stay sane holding that bad luck charm vicl. t
I truly feel sorry for the Chums. They that one thing in common and that is that none of them ever learned the meaning or term of being in denial. t
littlekim, ISIS has two drugs on the market right now. Both have more potential than the drugs that vicl has. That isn't the issue, and what will make you sing a Rainy Night in Georgia will be the upcoming meds from them that will be blockbusters. No one can say they we weren't warned by the Chums, so Don't Get All Shook UP, and don't have things Always on My(your) Mind. You and the Chums need to be saying to each other Baby Let's Play House for when you get into the commune. It will be a Dark Moon over you Chums soon. You will be in Double Trouble over a Full Moon. You will call Johnny and Franky about your G. I. Blues from holding vicl and not listening about buying ISIS. You will keep on thinking about Getting Home Somehow, but with your low vicl share price you won't make it out of the commune. You will Have Hard Luck and Hard Knocks because you were a hard head. You will say Help Me because I'm Hot Dog. You will also say I Don't Want to Be Stung just because I was stupid and invested in vicl. I'm Indescribably Blue because I've been a vicl holder. It Hurts Me, I sure wish I would have listened to the ISIS holders.
That is OK LilKim, you've been channeling Elvis:
http://en.wikipedia.org/wiki/List_of_songs_recorded_by_Elvis_Presley Sell vicl and you'll be OK. t
flintstone, I know you probably don't have TV or the internet and you were over at your friend's house when you wrote me that nice note, but the situation remains the same ISIS up and the little v the same. You probably won't be able to see this for a couple of days until you get back over to your friends house or the library. I just hope that when you read this again that the little v is still standing. Thank you again for the nice note and help. t
It won't be with Mr. Beer at the helm for very long IMO. Also, based on earnings, if you give their drugs a value of three times sales then juxta is worth about $600 million and the new drug worth about $45 million. The company lost more money despite making more revenue and had a 46% drop out rate with juxta. t
flintstone, Last I looked it was the other way around, ISIS up 9 cents, the little v unchanged. So now it is by the year end and not this summer we will see this new vicl? We'll see, you seem a little bit angry too Chum. You best learn to like your fate, like Mental in Dumber and Dumber after he ate that hot pepper burger. "It'll be a lot easier if you just lay back" said Lloyd Christmas to Mental. How's Wilma, it is good to have a wife who knows how to live without elctricity for when you get the commune. t
littlerichard, I'm sorry to say I don't margin, but thanks for thinking of me anyway. You are going to be spanked all year long. If you continue to hold vicl you would be much better off learning to like the spankings than being so angry. Thank you also for your part in the reverse VOO-DOO curse. Did you get a bite of the pxx-pxx sandwich? t
Sell while you can before vicl hits the pink sheets. t
Genocea Biosciences reports Q1 EPS of ($0.64) vs ($0.56) estimate (9.81)
Cash, cash equivalents and marketable securities as of March 31, 2015 were $84.5 million, compared to $47.1 million as of December 31, 2014. The increase was as a result of public offering in March 2015 which raised net proceeds of $48.4 million. Genocea expects that these funds will be sufficient to fund its operating expenses and capital expenditure requirements through the third quarter of 2016.
GEN-003 -- Immunotherapy for genital herpes in Phase 2 dose optimization trial. $1 billion revenue opportunity in the US. Top-line results expected late in the second quarter of 2015. GEN-004 -- Vaccine for the prevention of infections by all serotypes of pneumococcus in ongoing Phase 2a human challenge study. Potentially disruptive to greater than $5 billion global market. Top-line results expected in the fourth quarter of 2015
New Chum, you need to look at what is going on with your vicl. 10 cents away from safety from the pink sheets. Even though you are a rookie Chum, and somewhat angry your reverse Voo-Doo curse is greatly appreciated. Any of your friends that bought a Mercedes on credit waiting for the old gray mare....vicl to help make the payments will see their Mercedes repossessed. Your right that your group did help make the ISIS shareholders rich and thank you again for that. t
The sooner the Chums get a place and move on the better their mental health. They don't realize it but they have given up over ten years of their lives doing this. One day they'll realize that they gave up valuable time, supllied no useful info, and they are out a bundle holding that dog vicl. They have been fabulous with their reverse Voo-Doo curse and again I thank them and their friends for helping my friends and my family get a lot better off. More torture coming for them this whole year. You have to admire their meddle though. t