It is all #$%$ Boxcar. Here is the info that I've discussed with my friends:
1)I wonder what the definition of an ISR is here. I do know that with Lovenox about 30-40% of the time people get a big bruise at the injection site. No, technically that is not an injection site reaction because the med is acting as it should as an anticoagulant and thus technically the med is just demonstrating its action. But from a disconcerting standpoint it is significant with patients, I see it every day. So a pharm rep who is trying to sell the drug will see it that way, a patient who said the shot hurt and left this "big bruise" will see it another.
2)The drug has not yet been promoted for going after this indication at all. It was a POC and as you noted Phase II. But if it were going after elective joint replacement surgery that would not be that big of a deal to use it compared to what that KOL said. Most orthopedic surgeons are so busy that they usually have to schedule your surgery for a joint replacement about a month out. In my state you can't get preop blood work, other testing, and medical clearance longer than one month from surgery, but I'm sure the drug could made to be given within that time frame.
3)As far as having a 70 day time frame or somewhat longer before you see values go back to normal with Factor XI after the use of ISIS drug, as long as there isn't permanent damage in your ability to restart up the manufacturing process of Factor XI itself I don't see the big deal for this as a problem. Latest literature has been devoted to the patient who leaves the hospital and develops a postop VTE within 20 to 35 days postop after a joint replacement surgery. In fact I tell people that if they get any mysterious swelling in either leg.....even the un-operated one, or they get mysterious shortness of breath for up to six weeks after their surgery they are to report to the Emergency Dept.
You've watched too much Dr. Ruth on TV with all of your analysis of everyone. The info is real, it is risky, the data coming out soon. People are all adults here and if it doesn't make it people are preparred for that. Keep trading and I hope you don't get a fat finger. t
I'd change my name before I called anyone a moron as a moron outranks a monkey any day. Better yet find a new board with a stock that you support. Know that won't happen so you will be continue to get spanked over here with ISIS hitting new highs probably at least monthly. I remember watching your relatives in the zoo in Tampa chewing gum....you might take that up to relieve your stress from the spankings. t
Again, you need to keep what happened to you at the McDonalds X-mas party to yourself. If someone took liberties on you don't suffer turn them into the authorities. t
Most ISIS people have gotten in well below $14. If you were honest you'd own up to insulting them for many years and knowing that ISIS wasn't that high until just this year. Of course it will surpass that high before the next six are over and I would be that vicl will be below a buck 38 in that same time frame. Time will tell. An honorable person would leave once vicl goes BK, but rather an honorable person who has no interest in ISIS wouldn't be here in the first place. t
Tanya Harding for CEO to fight back!!! t
I agree KG, Zack's knows nothing. My parakeet could out predict them. Hope you are doing well BTW and it is good to see you here. Take a look at SCMP and their prostones pipeline. Maybe catch up with you over the holidays. Tell your neighbor JP there on the lake I said hi. t
I've seen a lot of talking heads on SA that berate the stock and other biotechs and they don't know a thing about the science, technology, competition etc. It goes both ways. t
I would venture to say that anyone here who is positive on the stock also know the risks. If they didn't you have warned them about fifty times. Bottom line this is the real world and people know they are playing with real money. Your tilt is toward your aspect, so be it. but after 50 times why don't you actually show something negative or wait before you comment again and have real negative news before the same-thing over and over and over again. t
You need to listen to your own advice. I'd ask myself why the stock has been able to hold around the 70 cent level despite not having earth-shaking news for so long? I would also ask myself what are the real facts as to why, who the competition is, what are they trying to accomplish, and how does the data look? Despite your ranting to the negative the stock holds its own ground. Maybe shareholders are more objective than you are. Everyone knows that this is a lotto stock...kind of like that insurance commercial, but people here who are lucky enough could make a real million bucks, not have that many bucks(not deer) in their backyard. t
What if it doesn't come true....then will it be wait until March, then wait until July then wait until the CUBS when the pennant. Macro you should contact your step-brother Microsanuff from Germany and ask him what happened to COTT when he said to sell ISIS at about 5 and buy COTT at six. Check the price comparisons on your own without running them through your Putin screen as to what is real data. t
You'd be lucky buddy if you could get to be Boy Scout Troop leader of Troop 2319. I'd say wheresyourCV. t
You come over to someone else's house, drink their beer, lay on the couch, try and control their remote to the TV and you still insult the host......you need to go to finishing school. t
Buddy I'm not bitter. My average cost is about 11 bucks including the large purchase recently. I ask you to swallow your pride and think about your family. Companies like KITE, BLUE and others are going to eat vicl's lunch....but don't let them take away your grandchildren's lunch just to try and save face. t
Dr. Andy Dorr is a loser who had many things against him. Where is he now? I heard that he was going to run for president on the Clondike Party ticket. t
American Greed is a show about where tricks are played and people are left in the lurch. Like when a study is done, results are known, people on placebo actually did much better than the people that are supposed to be on "high tech" medication and you withhold results like the CEO of vicl. Write into CNBC and maybe you can get some cash to make up for your vicl losses. t
You shouldn't be telling everyone what you did at your last X-mas party at McDonalds. More info than we need to know. t
You have no facts, you live in the past. You and your friends quotes about share prices between the two companies over the last year are FALSE. Over one day trading, 5 days, two weeks, one month, 3 months, 6 months, one year, two years. Anyone go to the Yahoo graphs and plug in the data comparing the two companies and the Keystone Cops...I mean vicl, they lose every one of those time dates. Now there may be more employees at vicl that own more parakeets than employees at ISIS but that hardly qualifies beyond Petsmart liking them better as good for anything. I think the CEO of vicl should apply in Argentina for the job of finance manager. He could keep on telling the people things are getting better and use his expertise on delaying data to help out the governement. I know I'd hire him for that if I were them. t