A lot of pain coming for the chums in the short and intermediate term. IMO at any time the SMA trials could be halted and the drug approved on a provisional basis. ISIS will have a poster at the First European Conference on Hereditary TTR-amyloidosis on Nov 3rd. Three non-aligned experts on TTR-amyloidosis recently gave ISIS drug for this treatment an excellent review noting that it was as potent as the competitor, with distinct advantages, and it had lead time of about twelve months over the competitor. With the distinct advantages that the Factor XI inhibitor has for no risk of bleeding and yet full anti-coagulation it is very possible that this drug could be approved for use by 2018. Thus you have a possible approval for the SMA drug in 2016 or earlier, a possible approval for the TTR-amyloidosis drug by 2017, and the Factor XI inhibitor being approved in or around 2018. The other interesting thing to note is that Bayer's Xarelto goes generic in about five years. For Bayer to remain active in the anti-coagulant space they need to really position the Factor XI inhibitor for use ASAP. t
If part III didn't go through the most important slide in that CC was slide #8 of the 33 slides for long-term potential.
The negatives are as I noted before, some people want that deal with big pharma signed and delivered like right now. The value of these drugs....any one or possibly all will go up five fold if they do wait and have positive results. Again, a risk, but a risk probably worth taking. t
But if we look at the situation as it is now, they continue on as noted before. There time tables have been set, their monies should hold out if their projections for spending remains on tract. The other nice positive is the fact that they are still seeking the toxic dosage and they haven't gotten there year..
I have listened to the CC twice. The bad issues are that there is basically the same presentation as before BUT with the exception that we are farther along in regards to time and things are progressing from what I can see as planned. This is a lotto stock to be sure.
Testing....can't even get a message through with this Yugo equivalent. t
I heard that you chums were told that any money spent on vicl was going toward owing the real estate of vicl. It is located in Belize and known as the Blue Hole. t
Is it like August like you said before vaccinechum? Or is it Oct like you said recently? Or is it two years from now like you are saying now? Good luck with all of your uninformed information which translates to uninformed advice. t
Please tudywad quote how much ISIS was down today and how much vicl was up. Also further projections in price comparisons over the next three months would be helpful. TIA you always have extremely important information and you have been right on the money......just like you said that vicl would move up in Oct. t
Hey bozochumnypayingtoomcuhtaxes, please tell us if you have the confidence, how much you have in vicl, and how much more you have to potentially left to invest vicl? If you don't have anything to hide that should be an easy answer. TIA, t
Please Nydummychum tell us how much money that you have committed to the blue hole and how much money more you have available for further commitment to the blue hole before you have to move to Belize because you are bankrupt? TIA, t
I don't get any friendly encouragement or recognition but that is the truth, please take a look at old postings. I feel confident that the shorts are going to get fried. They have neither the knowledge, background, or patience to understand what is transpiring. I only hope that Dark and whatever octopus roots that he has protects himself against what is going to transpire in both the short and intermediate term. Whatever the chum group is espousing doesn't mean anything when people are looking at the SMA drug. This drug is being used in new borns. It has been used without ANY, I repeat ANY side-effects in going on three years. I would post a video showing a patient with and one without treatment but Yahoo will not allow it. The differences are staggering. ISIS will go up at least 15 points once the drug is approved with a provisional approval and that will be all that is necessary. t
chumdog, You've been warned, at any time the SMA drug could get a provisional approval. You chums also don't realize or fail to want to recognize that Mipo has been out for almost three years. There has been no news with ANY liver toxicity and I'm willing to bet that there won't be. In any case, you chums will all be looking like xxxx for brains soon. I promise to not rub it in and be regle once the news breaks. t
Nothing could be farther from the truth. If I liked vicl I'd buy it. It it had up-to-date technology and a pipeline I'd buy it. Keep crying your crocodile tears. Jealous, snoopy, sexist, and stupid is no way to go through life son. t
You are being a sexist and jealous by calling people girls. Many girls could kick your tails and many people would know enough not to buy vicl the soon to be a pink sheeter.....hey they could be raising breast CA awareness. t
Mipo is still on the market and still growing in regards to use. So what BS you want but you don't know too much. t
Anyone have a copy of the transcrpt? I'd be happy to review it. I'll check around myself too. Bcpiii, any info. TIA, t
They aren't tough to get. They fall in place for purchase two cents under you bidding price. t
Because you are a carpet muncher doesn't mean everyone goes your way. t
The chums will be having.....I hate to say, dead sparrows fot Thanksgiving. They will then move the game chains back again in claiming when vicl is going to make it big. The chums are little people with little money. When one chums states that he is going all on AGAIN on vicl it really means turning in a few coupons at albertson'd for about 39#$%$ and buying A share of stock. They have done that move hundreds of times and thus surely they shoould have at least a couple hundred shares. t
You are lining yourself for future criticizing if you are going to try and point out arrogantly a little mistake here on spelling, the big mistake is to be a do-do bird and to love vicl which is maybe the biggest loser in the biotech investment world. t