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Isis Pharmaceuticals, Inc. Message Board

jetmanbash 261 posts  |  Last Activity: 1 hour 22 minutes ago Member since: Dec 29, 2004
  • Reply to

    The drug works

    by jwsull Oct 31, 2014 1:05 PM
    jetmanbash jetmanbash Oct 31, 2014 1:25 PM Flag

    Wait and see if the drug isn't in question. t

  • jetmanbash jetmanbash Oct 31, 2014 12:47 PM Flag

    It was an artificial prop by Mr. Beer to increase interest. Also, I'd bet that the money he lost with that ploy didn't approach the money he made before when the stock was going for over a hundred. t

  • jetmanbash by jetmanbash Oct 31, 2014 12:42 PM Flag

    They don't charge as much for their product, they have potentially more patients, and they have some other drugs in their pipeline....not AEGR though. t

  • trouble it is in the same family as juxta, and as part of the craftiness of Mr. Beer it was bought solely to make sure that they controlled the potential competition. That sage kelly is off on work leave and it was heavily hinted upon by a co-worker that this is the tip of the iceberg with him. I listened to the CC last night and I've never heard as long of a preamble as I heard in regard to theirs about warning about forward looking statements(a preparation to anticipated huge new lawsuits IMO). And I have never heard so many big words used to try and explain away the diarrhea. They noted how they misjudged its effect....really?? On a 23 patient study with everyone under total control, your control, and no fudge factor in there for human nature as your basis to make that judgment? They had their so-called compliance ratio where there would be less people dropping out than if you had prescribed a statin drug!! t

  • jetmanbash jetmanbash Oct 31, 2014 12:08 PM Flag

    You should send him a bottle of wine, it's legal and he did do you a big favor:)) t

  • jetmanbash jetmanbash Oct 31, 2014 12:05 PM Flag

    I'd bet that his coronary arteries like a 70 year old, thing is he doesn't know it. Maybe he should be on juxtapid....nah, his liver couldn't take it. t

  • Reply to

    here's my take on the CEO

    by tnorman61 Oct 31, 2014 11:58 AM
    jetmanbash jetmanbash Oct 31, 2014 12:04 PM Flag

    Sure the share price. But if you are on cocaine that could affect your mind during regular business hours. There also is a problem that is called organic brain syndrome. If you are an alcoholic and you do go on the wagon it takes about six weeks before you really can think into the abstract again. So in order for your advice to ring true Mr. Beer should go, otherwise you have a captain driving the ship who could smash it into the rocks. Kind of like that Italian captain who was supposed to go down with the ship and he jumped into a net to safety and said that the ship rocked him into it and he really wanted to be back on the ship helping the people going down with the big boat. t

  • Reply to

    AEGR's worth:

    by jetmanbash Oct 30, 2014 10:57 PM
    jetmanbash jetmanbash Oct 31, 2014 1:02 AM Flag

    A pretty good technician friend of mine is saying short it down to 8. t

  • Reply to

    read aegr eps report from aegr webpage

    by loser2014may Oct 30, 2014 10:50 PM
    jetmanbash jetmanbash Oct 30, 2014 11:38 PM Flag

    The window is closing for these guys in regards to time. They said that no PCSK9 inhibitor will work on patients with HoF. They won't always work, but with the price differential in regards to probably something like $30 K per year vs. $350K per year I would bet that many insurance companies will make patients try the PCSK9 inhibitors first. Mipo is moving up fast too. A better drug than AEGR, Mr. Beer, and cronies like JS, Ms. Yang, and sage kelly wanted the market to see. With their new dosing schedule they like they are doing in the FOCUS trial for HeF there are much less ISR's. The data despite what Chesarus says was excellent post hoc for the small population that they had to work with. And the liver enzymes issue is much less with Mipo than the cronies had the public to believe. So so many unethical things here. Mr. Beer celebrating at the Waldorf-Astoria with maybe the most expensive room in the place. Someone putting in the press that the FDA was going to review the "cancer risks of Mipo" on the actual FDA prelim committee meeting......doesn't the FDA review the cancer risks for all drugs going up for evaluation as well as ALL OTHER variables? Mr. Beer has to raise the price due to demand. Mr. Beer won't give out new start data anymore. The CFO states that Mipo has almost no one on that drug. The raising the price of juxta due to DEMAND?? JS an analyst also an investor in juxta, Ms. Yang persistently putting a target price on ISIS of 9 dollars a share....I believe she still has that. JS hosting alot of the CC and throwing softballs to Mr. Beer, but also hosting the ISIS CC's and showing almost no interest, but really there for spy purposes. A survey FUNDED by AEGR and released like a scientific survey in regards to how many more lipidologists were going to use juxta over Mipo. The truth is that juxta is oral, but it is not safer on the liver. It is not safer or has a lower CA risk. The emperor has no clothes..two ways. t

  • Weekly Overview: A Perfect Storm Ahead for Avian Flu?
    30 October 2014

    GLOBAL - With the start of November just ahead, those of us in the northern hemisphere are preparing for winter and it could be that we should also be making arrangements for a powerful flu season.

    The Chinese veterinary authority this week reported finding no less than five different subtypes of the highly pathogenic avian influenza virus during September, apparently during a programme of national surveillance on one day. The types were H5N1, H5N3, H5N8, H5N6 and H5N2.

    The great majority of the 51 'outbreaks' reported to the World Organisation for Animal Health (OIE) were virus-positive samples taken from birds and the environment at markets. However, at least two poultry flocks were affected; all the birds there were destroyed.

    That there were so many positive samples over such a wide geographical area and of so many types is cause for concern. The next pandemic affecting humans or livestock or both is likely to emerge under circumstances just like these. Flu viruses are more active in cool weather and, were one highly pathogenic type to cross with one that is easily transmitted, we could be facing a perfect storm for the development of a pandemic.

    In the meantime, cases of H7N9 flu in people continue to rumble on in China. Two cases were reported in August and a further two last month, bringing the total number of cases to 440 in mainland China. According to a case series kept by FluTrackers, the overall total now stands at 456 cases.

    A spokesman from Centre for Health Protection in Hong Kong has warned that more sporadic H7N9 infections are expected in affected and possibly neighbouring areas and that heightened vigilance is needed.

    This company is selling for five times vicl, but it is more than five times better, and has more than five times chance to be still five times more valuable still. t

  • jetmanbash by jetmanbash Oct 30, 2014 10:57 PM Flag

    The stock is worth the same as when it went public. They will have all kinds of turmoil in getting rid of Mr. Beer(bad penny), handling the old lawsuits, handling the new lawsuits, laying off pharm reps, and COMPASS employees, maybe doing another stock offering. SNY should buy them and then control the HoF space. However the French fired their CEO yesterday. t

  • Reply to

    Sex Drugs and Biotech

    by ryan_dts70 Oct 28, 2014 4:13 PM
    jetmanbash jetmanbash Oct 28, 2014 10:10 PM Flag

    Ryan he's a real sociopath. Just like when he had to raise the price of juxta due to increased demand?! And then the almost crying in one of those interviews about people having a lethal level of lipids going through their arteries every day. True, but way overacting and really for self-gain. When you use cocaine by the way, in that first hour after using it you have about a 2400 times risk of having an MI all other things being he really should be crying for himself as he is making his coronary arteries go into dog year time span in regards to his own survival. t

  • jetmanbash jetmanbash Oct 27, 2014 10:21 PM Flag

    If a company has a really desirable product in these times of the patent cliff that company doesn't have to panic. Having enough cash on hand to last about three years at present spending rates affords you that luxury. Partnering too early, especially if you know that you have the products that are of value will see you short-change yourself. ISIS has an ApoCIII inhibitor that they are holding for a longer period of time due to its huge value and potential for multiple uses. t

  • jetmanbash jetmanbash Oct 27, 2014 9:19 PM Flag

    vicl is 17 cents off from the low of the year. VNN is wondering if it will hit the low for the year first, or ISIS hit $60 first. Only their hairdresser knows for sure none of them ever will. VNN newscasters are predicting once vicl goes BK many of them will be found on the streets muttering "Rosebud." t

  • jetmanbash jetmanbash Oct 26, 2014 5:08 PM Flag

    You might want to take a look at Roche's purchase of Santaris, a Dutch ANS company that uses LNA's(Locked nucleic acids) before you get too dogmatic. The pipeline with LNA's is certainly unproven, and up until this point they have always been considered potent but toxic. Mab's have had a slowing in their progress to a certain point and the RNA companies will be able to do things that small molecules and Mab's won't. There is tremendous potential here and it is high risk. So investors have to weigh those variables. But to try and dissuade everyone with the same message over and over again doesn't do any good. We will know within about 4 to 6 months if the progress is there. Sometimes the little guy does make it big and I think that this is one of those times, ADXS certainly was able to over come those odds, and I think this company has it all over on them. t

  • jetmanbash jetmanbash Oct 26, 2014 10:39 AM Flag

    As the BeeGee's would say vicl is "barely alive." t

  • jetmanbash jetmanbash Oct 26, 2014 10:37 AM Flag

    Did you ever think about moving to Cuba and get a job in their propaganda department? Sending quotes this board with CV would certainly get you the job. You could be the head of the fuzzy math division. t

  • Reply to

    Any Word on This Quarter's Sales?

    by aniustudent Sep 16, 2014 9:24 AM
    jetmanbash jetmanbash Oct 26, 2014 10:13 AM Flag

    If those things are true it puts everything in regards to his judgment in question. Feel bad for his kids as well. t

  • Reply to

    Any Word on This Quarter's Sales?

    by aniustudent Sep 16, 2014 9:24 AM
    jetmanbash jetmanbash Oct 24, 2014 10:19 PM Flag

    Yes really appreciated?! t

  • Reply to

    No conviction

    by tonytiger706 Sep 19, 2014 10:55 PM
    jetmanbash jetmanbash Oct 24, 2014 10:19 PM Flag

    You mean the breakdown?! t

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