Wed, Jul 23, 2014, 12:55 AM EDT - U.S. Markets open in 8 hrs 35 mins

Recent

% | $
Click the to save as a favorite.

ACADIA Pharmaceuticals Inc. Message Board

jyardagg 47 posts  |  Last Activity: Jun 2, 2014 12:47 PM Member since: Aug 21, 2012
SortNewest  |  Oldest  |  Highest Rated Expand all messages
  • Reply to

    bashing not justified, wiseguys and punks,

    by jyardagg Jun 2, 2014 8:03 AM
    jyardagg jyardagg Jun 2, 2014 12:47 PM Flag

    feurestein is a prime example of a wiseguy punk.

  • bashing of nwbo is not justified when the early DC vax L results had survivals of GBM over 36 months.

    Adam's bash that the placebo group was from historical data is nor justified because the norm of GBM is about 14 months. Ted Kennedy kived 15 mo's after GBM diagnosis and had the best care possible but did not get DC Vax L. What if he did?

    The DC vax L treatment has been approved in Germany by the German FDA.

    In the direct case, even though a tumor increased in one case it was made up of largely dead cells upon examination. The treaments are on going in many patients who classify as hospice type conditions and are showing positive responses with just one tumor being injected directly.

    All the short wiseguys here including Adam should show some respect .

    how many trials do they allow the placebo group to crossover after progression? that says a lot right there for the hope behind the process. the event is progression or death. these are life and death decisions being made for each patient.

    people should show a little more respect for what's going on here and wait the data. It's not late the DMC assigned a continue and will be updated after the 88th event analysis.

    wiseguy bashers and gamblers should adjust their hats from backwards to forwards. Don't be a 50 cent wiseguy punk.

    the data will speak when it's ready to and the DMC is done analysis after the 88th event.

  • jyardagg jyardagg May 28, 2014 8:37 PM Flag

    are you stupid or what? I own some nwbo. just waitin on more facts, I hope the two both succeed but won't pump hope.

  • jyardagg jyardagg May 28, 2014 8:08 PM Flag

    I thought he said he knows it and likes the other better.

  • in the case where the tumor grew but was made up of dead cells when they looked.
    so what dies that say? somethings working.

    and these people =had not finished treatment so the story still has to play out.

    and only one tumor treated per patient.

    sheesh adam is a spin doctor of doom n gloom not truth,

  • Reply to

    my some shares

    by jyardagg May 27, 2014 3:11 PM
    jyardagg jyardagg May 27, 2014 3:29 PM Flag

    not on the fence, I'm in some, been in some and waiting on results.
    will never put expectations on it though, I know the bar is high at the finish line

  • jyardagg by jyardagg May 27, 2014 3:11 PM Flag

    hope the amazing is happening in people with inoperable cancer and they are beinig helped.

    if so the sky is the limit.

    people do well and this stock could see 100

    not pumping but not backing off on my hope,

    still not putting expectations on it.

    but some hope is there.

  • Reply to

    this stock should be trading in the teens

    by buyim200 May 27, 2014 9:19 AM
    jyardagg jyardagg May 27, 2014 9:37 AM Flag

    If this treatment by nwbo works significantly in cancer patients where nothing worked before the sky is the limit. the key word is significantly,

  • Reply to

    Adam really mislead the masses about something

    by jyardagg May 23, 2014 6:47 PM
    jyardagg jyardagg May 25, 2014 10:22 PM Flag

    benny, I know why people pay attention to the guy. Cause on the average he beats the averages in betting against small cap biotech and shorts love to target his short picks it doesn't matter why/ the stock is now tainted as a stock with shorts and only performance can beat them, they are confident nwbo will fail and are here to stay until the final count, it is what it is,

    I hope nwbo beats the averages , I'm in some, but don't expect much, still, I would like to be amazed and see pfs and os numbers beat the odds on dc vax L. just not counting on it,

  • Reply to

    Adam really mislead the masses about something

    by jyardagg May 23, 2014 6:47 PM
    jyardagg jyardagg May 24, 2014 9:40 AM Flag

    I say it's a coin toss because on one hand we have signs that people in the mean with GBM who got DC vax L live longer than 15 months standard that even Ted Kennedy experienced. On one hand we have signs that the broad antigen approach of DC vax L works to combine in not yet fully understood synergistic ways that more targeted approaches like imuc's have failed statistically,

    And on the other hand we have those, many, in Feurerstein camp that believe the broad DC Vax L response would be too weak to cause a drastic human immune response to help people fight off the effects and tumors of brain cancer.

    each hand has arguments and counter arguments. One hand fights the other. it will be that way all the way until the final count.

    can they meet 6 month pfs advantage or overall OS survival advantage in the numbers? even with the early data of 36 months we all know early data is subject to the proving in larger trial. I want to believe they can but being disappointed in issues of this nature i realize its a high bar to meet.

    hope the amazing happens but don't expect it.

    50/50. toss a coin.

  • Reply to

    Adam really mislead the masses about something

    by jyardagg May 23, 2014 6:47 PM
    jyardagg jyardagg May 24, 2014 1:42 AM Flag

    bottom line is he doesn't believe that it will meet the statistical bar so he derides every thing they say or do along the way, he will state things as fact that still have yet to play out in the scientific process.

    it is unknown as to the full human response yet Adam presents his guesses as facts and derides nwbo for stating anything positive.

    he thinks he is the anti pump but is the negative spin doctor himself over the top in trying to find negative things .

    but people seem to live longer on DC vax L with GBM. why? we have to wait to see the numbers and adam's guess as to why it will fail is as good as a guess that it will succeed. same as calling a coin toss in mid air as a fact.

    we have to wait to see,.

    I now discount the Gernan PEI because no follow thru as the whys but it adds to the plus side anyway,

  • Adam states that a DC vax L update is overdue. Incorrect.
    The DC vax L first look resulted an a continue at the 66th event to be looked at again on the 88th event,
    In a continue on the first look the efficacy result is always pending until the next look.'
    nothiing is "overdue" on DC vax L and the Phase 3 study goes on, the longer they take the better.
    Adam and other shorts deriding comments on DC vax L being overdue are just frustrated short sided thinking with no basis in fact.

    it will takthe 88th event and subsequent DMC anaysis to see.

    but nothing's overdue.

  • Reply to

    This is what you need to do till ASCO ..

    by steven511825 May 22, 2014 8:54 AM
    jyardagg jyardagg May 22, 2014 9:58 AM Flag

    likely whatever is reported on direct will be immediately derided by Feurerstein or some short hedge guy on SA. any pop will be shorted by hedgies and they will continue unless or until statistical efficacy is proven.

    this stock is now a classic short target and only real performance can free it from their grip.

  • Reply to

    For the life of me

    by saco1923 May 21, 2014 10:21 AM
    jyardagg jyardagg May 21, 2014 10:49 AM Flag

    the market knows that anything positive that comes out of asco will be immediately derided with negative short arguments by Feurestein or other short hedgemen betting against the issue..

    So that challenges nwbo to come out with meaningful results as can be for this stage of the game in the dev process.

    anything with a hint of uncertainty will be spun badly by short interests.

    longs know the game they play.

    need to see real performance.

  • jyardagg by jyardagg May 21, 2014 8:36 AM Flag

    waiting on the DC vax L 88th event after the continue and an update on direct.

    those are the results that matter.

    any spin either way is bs to me.

    long some nwbo.

    50/50 shot at something amazing or not.

  • I'm long some nwbo,

    don't give a flying uknow about the tit for tat going on here w Feurestein Vs Linda.

    waiting on the next update on DC vax L and what is going on w direct in more patients.

    I don't expect a DC vax L update until after the DMC assessment at the 88th event.

    They continued period.

    will let the performance of the two compounds do the talking one way or another. a success in either one or both will be astounding.

    I assign it a 50/50 proposition at either something amazing or failure to meet the numbers.

    my expectations are not real high about 50/50 but my hope is the amazing does happen.

    I expect more articles from Feurerstein or his short hedgeman skerelli will come out that diminish the odds in their short sided views. they do that, but they will probably wait for any run higher and then do their usual hit job on the hope.

    be ready, that's what they do.

    Only performance will speak to me.

  • when you read Adam#$%$ piece you get the impression that there is one patient.

    but then read the PR/
    "The Company plans to announce further case study information prior to the annual ASCO conference, while it continues collecting data from the trial. Although the trial is still at an early stage, with many of the patients only part way through the treatment regimen, the Company also plans to provide overall information about the data to date by the time of the ASCO conference"

    and When you read Adam's you think that the injection needle was responsible for the tumor reduction. But then if you read the PR you see that there was what appears to be other tumors responding that were not touched which would mean a t cell response in the immune system.

    and when you read Adam's critique of DC vax L you think they are late.
    but they already announced a continue and until the next look the efficacy is pending as it always is in a continue. and thus no further DMC updates until after the next look on the 88th event.

    yet Adam's negative spin has an agenda behind it. Now he wants to manipulate the FDA to taking action because he suspects funny business. I think the funny business is coming from Adam. Except he's not funny supporting shorts.

  • Reply to

    Saving the best for last......

    by redhotserver May 16, 2014 1:34 AM
    jyardagg jyardagg May 16, 2014 2:21 PM Flag

    IMHO the idea of a public news "weekly case" is appalling -- that would cross a line. I hope they stick to data.
    ____

    why is it appalling to you? these would be case studies with no personal info, names etc. This stock has been under a short attack for some time. it would be like nailing down the shorts coffin on nail at a time. If adam can tweet that we are bagholders then nwbo should do what they have to do to counter the short spin as long as it is ethical.. I see no problem with presenting case studies that way.

  • Reply to

    Saving the best for last......

    by redhotserver May 16, 2014 1:34 AM
    jyardagg jyardagg May 16, 2014 12:48 PM Flag

    you write Let me guess, your hopes are 50/50?

    My hopes are quelled by the reality that the statistics of DC vax L have to meet the bar of 6 months pfsi in GBM and direct has to show a positive response in a lot more than one patient.

    But yes.my hope is higher than what you guess but my expectations are about 50/ 50 maybe a little lower just cause I know how these things often go. hoping its better than IMUC was. an "expert" on these matters once told me he thought Imuc's was far superior and I suspected he may be off on that but still take his view into my assessment of the odds here.

    yet I hold some in enough hope to stay long some.

    you have to realize that we are hoping for the amazing to happen and that doesn't happen too often in these endeavors , statistically that is.

  • Reply to

    Saving the best for last......

    by redhotserver May 16, 2014 1:34 AM
    jyardagg jyardagg May 16, 2014 9:19 AM Flag

    I hope you are right, but that's a rather optimistic view. when you came up with that view were you wearing your pair of rosy glasses? It seems plausible that there are more responders and we would hear of them at asco because one patient's response won't cut the mustard. the naysays will be all over a response from just one patient like flies on sheeeeet.

    But regarding DC Vax L, we haven't heard follow up on the whys whens and wheres of the German decision to approve. I hope it was beyond compassion and hope.

    o well, based on everything it still looks like a 50/50 #$%$ shoot at something amazing coming in hope for the people suffering.

    But I am in some so better deduct a few chances towards the downside.

    still, 36 months in early data for dc vax L and the mark is 6 mo's pfs. German approval and some hope keeps me in some nwbo.

    even with adam's and his short thesis and how he's been right on many small caps that turned out as failures.

    he is not used to having Co's respond directly to his negative spin so he has a special interest in killing any enthusiasm in nwbo. Adam just wants them to die quietly and his short hedgies get rich.

    that's the way they roll.

    I hope he's wrong this time but my expectations are not real high on the amazing happening.

ACAD
20.16-0.15(-0.74%)Jul 22 4:00 PMEDT

Trending Tickers

i
Trending Tickers features significant U.S. stocks showing the most dramatic increase in user interest in Yahoo Finance in the previous hour over historic norms. The list is limited to those equities which trade at least 100,000 shares on an average day and have a market cap of more than $300 million.