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Amarin Corporation plc Message Board

kavbrian 2 posts  |  Last Activity: Jul 20, 2015 11:24 AM Member since: Aug 17, 2008
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    Bodes well for Celestial

    by erniewerner Jul 20, 2015 9:27 AM
    kavbrian kavbrian Jul 20, 2015 11:24 AM Flag

    I listened to the CC but I cannot recall if they noted when CELESTIAL is due to read out. Anyone know?

  • Reply to

    1512

    by erniewerner May 31, 2015 10:50 AM
    kavbrian kavbrian May 31, 2015 12:41 PM Flag

    Correct me if I am wrong but doesn't Nivo work well when the tumors express PDL-1? Maybe Cabo will extend PFS and OS in PDL-1 positive and negative patients. There's a decent chance it will improve PFS and OS in the PDL-1 neg patients. I think that is the opportunity for EXEL.

    It will be interesting to see the data from the Cobimetinib/PDL-1 combination. If Cobi really does increase MHC Class I expression the Cobi/PDL-1 combo might allow Roche to steal the entire lung cancer market from BMY (while also saving EXEL from oblivion if METEOR should fail).

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