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OncoSec Medical Incorporated Message Board

kgrichard5 276 posts  |  Last Activity: 22 hours ago Member since: Feb 9, 2009
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  • That a number of kids will experience clinical efficacy in a variety of ways over the next several months. I pray for minimal side effects and a significant improvement in their (and their families) quality of life (QOL) and activities of daily living (ADL's) parameters. I hope Serapta and the FDA can expeditiously bring the NDA submission to the table by May/June. I also hope, though do not think it is absolutely critical, especially if the above is compelling, that dystrophin is validated with Etep. This will only make the data submission more convincing and persuasive. Yes, I do believe this will all eventually come to fruition. Even the most ruthless and insensitive bashers and shorts cannot wish AGAINST a revolutionary paradigm shift in children afflicted with DMD.

  • Reply to

    Is this a viable product?

    by dark_horse_player Feb 27, 2015 9:30 PM
    kgrichard5 kgrichard5 22 hours ago Flag

    The way I am looking at this, is LLBO is worth something again. Two years ago, I basically wrote it off as a total loss= Zero value. It may become that again...who knows. The fact that it has moved from .0001 to as high as .0017 is enough for me to at least grin. I will try calling Circadia Health Systems again and inquire about the strategy and viability of this product under their auspices.

  • Reply to

    Reuters mention

    by silverjeff862 Feb 27, 2015 1:11 PM
    kgrichard5 kgrichard5 Feb 27, 2015 2:04 PM Flag

    Absolutely. Can you imagine if we get the green light on DMD. Then a green light for additional Exons. Then an update on the 100 Ebola (hopefully very positive) patients in the same year. That will open doors to Marburg and Influenza funding and market exposure. Everything adds to the validation, breadth and depth on the SRPT enterprise. We finally be considered a multifaceted company, not a one shot wonder.

  • kgrichard5 kgrichard5 Feb 26, 2015 6:01 PM Flag

    Sorry on the percentage breakdowns. I meant 22.5 % not 23.3....you get my drift.

  • My old model of efficacy....20% by 5 categories (obviously major rounding)
    20%.....responders...clinical improvement
    20% stabilizer's...no regression vs. NH
    20% slowing of progression vs. NH
    20% equal to NH counterparts
    20% less efficacy then NH counter parts...not a negative, just the dynamics of the disease.

    Following the 168 data I am hoping for 10%, and 23.3 X4 ( sorry, I know that is maybe far too intricate of a break down)

    Safety upheld
    Dystrophin Upheld
    10% clinically improved (musculoskeletal/cardiopulmonary metrics)....Which is huge, even though 10% does not mean much...unmet disease state. ( Huge clinical efficacy)
    23.3....stabilization (efficacy)
    23.3....slowing of progression (efficacy)
    23.3..... equal to NH m(no effect)
    23.3....below NH (no effect.
    This is all speculation, but this why I am here.
    I do believe once on the market we can be more aggressive with dosing and frequency. Also, introducing Etep at an earlier age. More usage will help refine these approaches. GLTA...KGR

  • Reply to

    Recent activity.

    by impaidbyu Feb 26, 2015 7:50 AM
    kgrichard5 kgrichard5 Feb 26, 2015 2:07 PM Flag

    For 1 thousand dollars you get roughly 1 million shares. If the stock goes from .0010 to .0017....you make 70%. There is no news. Just a mega penny play that is tradable again as of a few months ago.

  • Reply to

    Questions and answers from CC

    by manferfish Feb 25, 2015 11:41 AM
    kgrichard5 kgrichard5 Feb 25, 2015 1:37 PM Flag

    Just for fun. Could you elaborate on some of the good reasons. It will give us some conjecturing while we all wait. TIA

  • Reply to

    What I liked the best

    by thigrlsrk Feb 24, 2015 7:24 PM
    kgrichard5 kgrichard5 Feb 24, 2015 7:32 PM Flag

    Mutual communication between the FDA and SRPT....that is what I want to hear. No more snags.

  • Reply to

    I am curious of folks thoughts,,,,

    by bcpiii Feb 24, 2015 4:27 PM
    kgrichard5 kgrichard5 Feb 24, 2015 5:00 PM Flag

    Bcpiii. So are you saying you have found a pre PR'd gem or pearl? If so, and it is positive, keep it to yourself just long enough to load up while the pps is stable. Then, of course, please share it with all of your wonderful message board friends. Ok. Did you buy your shares. Great! Now please share. KGR

  • Reply to

    Today is a huge buying opportunity

    by kgrichard5 Feb 24, 2015 11:55 AM
    kgrichard5 kgrichard5 Feb 24, 2015 12:25 PM Flag

    Winter. Precisely my point. We know the true value lies in DMD There is a small fraction of interest thinking SRPT could have been contracted for Ebola. The low volume demonstrates this is an artificial, "true value" sell off. That is why I believe today is a buying opportunity, due to ignorance from a small group of investors on a low volume day.

  • The sell off is due to competitive news regarding Ebola. Certainly a nice DMD discount today.

  • Bad news is usually delivered AH's on a Friday. That is behind us. Good news is often delivered on an early Monday morning. That is now in front of us. Just hoping decision has been made.

  • Reply to

    from the advocates

    by thigrlsrk Feb 20, 2015 8:01 PM
    kgrichard5 kgrichard5 Feb 21, 2015 11:16 AM Flag

    Thig, spot on post. The FDA should be leaning on their toes rather than back on their heels with PROACTIVE measures, to make sure the next submission has no holes in it. What bothers me most, is the FDA looking at the trial and changing course, leaving SRPT in a guessing game. There should be absolutely NO guessing at this point. I strongly encourage the FDA and SRPT to get together and make sure this submission is expedited ( May/June) and bullet proof. Enough is enough. Both parties are accountable for getting it right and should not be playing ego games with each other while families wait. Simply put....communicate and often!

  • Reply to

    Its a buyout

    by kimberlyjaie Feb 20, 2015 3:53 PM
    kgrichard5 kgrichard5 Feb 21, 2015 10:25 AM Flag

    Either way, we have about 12 months of market games ahead of us. I do believe that one positive finding supports the other. If PAD and stroke are compelling, SCD looks like a much safer bet, and if in 2016 Q1 SCD, is clinically impacted (positive).... vice versa. PAD and stoke comprise a multibillion dollar market...that is where the real long term value is. However, one step at a time. SCD clinical flare ups are much faster to ascertain, stroke and PAD require much harder endpoints and duration of trials...i.e. morbidity/mortality.

  • Reply to

    Getting ahead of it's self again..

    by ctsosavealife Feb 19, 2015 6:20 PM
    kgrichard5 kgrichard5 Feb 19, 2015 7:44 PM Flag

    True. However, in sepsis you usually can't travel for treatment. Currently, in the US, if you are hospitalized and become septic....no CTSO. Hopefully, that will change in time. I know that there is enough demand in the EU to take this to 50 pps over the next few years, however, as arrogant as it sounds, getting an FDA endorsement would be a huge catalyst. GLTA..

  • kgrichard5 kgrichard5 Feb 19, 2015 7:39 PM Flag

    Hofno...Thanks for the post. 2015 will be huge!

  • Reply to

    Short Squeeze

    by bbgun64 Feb 19, 2015 12:41 PM
    kgrichard5 kgrichard5 Feb 19, 2015 7:23 PM Flag

    LOL..ki2002, if I were totally selfish, I would have kept that close to my chest. Not that most longs don't already know the dynamics of what is to come, especially sitting at .84 cents and low volume. I am fully loaded and I'm sure you are as well, but if the opportunity knocks I have a little dry powder to add. Bashers galore, I love it! GLTY

  • Reply to

    Short Squeeze

    by bbgun64 Feb 19, 2015 12:41 PM
    kgrichard5 kgrichard5 Feb 19, 2015 7:09 PM Flag

    I have a feeling we will go over a dollar tomorrow as many shorts will cover before the weekend. I predict 1.04 to 1.08. The protest resolution is very very close, and being on the wrong side of the trade could be devastating. A Monday a.m. gap up is the shorts biggest fear. I know I will have a great relaxing weekend as the bottom is in for the longs. One caveat. One last bear raid push before covering. Any dips early in the day tomorrow, scoop em up.

  • Reply to

    I am considering

    by pearsby09 Feb 18, 2015 6:05 PM
    kgrichard5 kgrichard5 Feb 18, 2015 10:34 PM Flag

    Pearsby. I think you are harmless and certainly don't impact this investment. In fact, I think you would be a hoot to party with. I didn't vote for Clinton, but of all the Presidents he would be my partying favorite...imagine the stories. However, as the old saying goes...don't let the door hit you in the a-s. With congeniality for dissention...KGR p.s. glty sport. Time to shake up the psycho meds.

  • kgrichard5 by kgrichard5 Feb 18, 2015 6:36 PM Flag

    When you consider the value of this technology is .0011. However, amazing it has climbed from .0003 without news. Simply put, people like buying a million shares of anything...sounds fun. I own 5 million shares of XYZ. Better than a pock in the eye with a sharp stick....but will it keep going, stabilize or suddenly collapse once the accumulator's cost basis allows for a substantial dump...or, is there something to this. Inquiring minds want to know.

ONCS
0.3749+0.0009(+0.24%)Feb 27 3:53 PMEST

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