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Fortuna Silver Mines Inc. Message Board

king_tuts_jewels 180 posts  |  Last Activity: 22 hours ago Member since: Sep 11, 2003
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  • king_tuts_jewels king_tuts_jewels 22 hours ago Flag

    Hey UGT, I'm flattered you put me in the same company as these people. You've touched on about every aspect of GALE's success. I don't think these shorts can read! One thing that intrigues me is the hiring of Margaret Kivinski. Read her bio and ask yourself why Galena acquired her. Something is in the works and probably be mentioned at the earnings CC!

    Sentiment: Strong Buy

  • Reply to

    Weak Longs - taking the bate again

    by whiskey8860 Jul 28, 2014 10:45 AM
    king_tuts_jewels king_tuts_jewels Jul 28, 2014 10:53 AM Flag

    Earnings is 8/11 after market close.

    Sentiment: Strong Buy

  • king_tuts_jewels by king_tuts_jewels Jul 27, 2014 4:57 PM Flag

    Of the women diagnosed each year with breast cancer, only about 25% are high over-expressors of HER2, or IHC 3+. This Phase 2b trial targets the approximately 50%-60% of these women who are HER2 low to intermediate (IHC 1+/2+ or FISH

    Sentiment: Strong Buy

  • king_tuts_jewels by king_tuts_jewels Jul 27, 2014 4:52 PM Flag

    Abstral® treats breakthrough cancer pain in patients already being treated with opioids. The product contains the pain-relieving substance fentanyl. Abstral allows doses to be customized according to individual requirements, which is essential for achieving optimal pain relief.
    Abstral is a rapidly disintegrating tablet that is placed under the tongue. The advantage is that the active ingredient is absorbed into the body through the mucous membrane. The effect is thereby fast and predictable. The tablet is easy to dose, store and handle.

    Sentiment: Strong Buy

  • king_tuts_jewels by king_tuts_jewels Jul 27, 2014 4:48 PM Flag

    GALE-401 is a controlled release formulation of anagrelide with product attributes that differentiate it from the currently marketed immediate release formulation. Anagrelide is a drug that has been shown to slow down how fast platelets are made in the bone marrow, and has been approved in the U.S. and Europe for treating high platelets counts in patients with bone marrow disorders.

    Anagrelide is currently approved and indicated for the treatment of patients with thrombocythemia, secondary to myeloproliferative disorders, to reduce the elevated platelet count and the risk of thrombosis and to ameliorate associated symptoms including thrombo-hemorrhagic events. Patients with these disorders have extremely high platelet counts, which can cause strokes and heart attacks. Whereas the normal platelet count is 150 to 400,000 per microliter, these patients may have platelet counts greater than1 million. Common side effects of anagrelide, such as palpitations, tachycardia, and headaches, are believed to be associated with maximum or peak plasma concentrations following administration (Cmax). These side effects often limit dose escalation and may result in inadequate control of disease or discontinuation of therapy in over 20% of patients.

    Sentiment: Strong Buy

  • king_tuts_jewels by king_tuts_jewels Jul 27, 2014 4:46 PM Flag

    GALE-301 is a folate receptor alpha-derived, peptide-based cancer immunotherapy administered to HLA-A2 positive patients in combination with granulocyte macrophage-colony stimulating factor (GM-CSF) as an adjuvant treatment to prevent recurrences in high-risk ovarian cancer patients rendered disease-free after completing standard of care therapy.

  • king_tuts_jewels by king_tuts_jewels Jul 27, 2014 4:43 PM Flag

    NeuVaxTM (nelipepimut-S) is the immunodominant nonapeptide derived from the extracellular domain of the HER2 protein, a well-established target for therapeutic intervention in breast carcinoma. In this case, approximately 25% of resectable node-positive breast cancer patients, despite having no evidence of disease following surgery and chemo/radiation therapy, will still relapse within three years. Increased presence of circulating tumor cells (CTCs) indicate decreased Disease Free Survival (DFS) and Overall Survival (OS) – suggesting a dormancy of isolated micrometastases, which over time, lead to recurrence. The nelipepimut sequence stimulates specific cytotoxic T lymphocyte (CTLs) following binding to HLA-A2 or A3 molecules on antigen presenting cells (APC) to elicit a robust, specific and durable killer CD8+ CTL response. These activated specific CTLs recognize, neutralize and destroy, through cell lysis, HER2 expressing cancer cells, including occult cancer cells and micrometastatic foci. The nelipepimut immune response can also generate CTLs to other immunogenic peptides through inter- and intra-antigenic epitope spreading.

  • Reply to

    GALE vs. PBYI

    by pmknauf Jul 22, 2014 9:05 PM
    king_tuts_jewels king_tuts_jewels Jul 22, 2014 9:24 PM Flag

    Forget PBYI, if NeuVax ia approved then your estimates are very low. NeuVax is a vaccine with virtually no side effects just about like getting a flu shot. With an SPA from the FDA and the DOD on board, the the sky is the limit.

    Sentiment: Strong Buy

  • king_tuts_jewels king_tuts_jewels Jul 22, 2014 10:02 AM Flag

    So, so, true

    Sentiment: Strong Buy

  • king_tuts_jewels king_tuts_jewels Jul 22, 2014 10:01 AM Flag

    GO GALE!!!

    Sentiment: Strong Buy

  • Nobody believes one word he says now!

    Sentiment: Strong Buy

  • Reply to

    Q2 Earnings Date

    by gene4346 Jul 17, 2014 10:02 AM
    king_tuts_jewels king_tuts_jewels Jul 22, 2014 8:02 AM Flag

    I just emailed Remy and she responded very quickly. You are correct, GALE's earnings are to be reported on August 11 after market close. Good luck to all longs. It looks like a good day for Galena!

    Sentiment: Strong Buy

  • king_tuts_jewels king_tuts_jewels Jul 18, 2014 3:07 PM Flag

    Would you mind telling us the file number or case number of that "probe"? The only probe is sticking up your *#@%?/^&

    Sentiment: Strong Buy

  • Lowest it's been in two months. ABSTRAL may be getting strong market share!

    Sentiment: Strong Buy

  • The shorts will be scratching their heads this long 3 1/2 day weekend. GO GALE!

    Sentiment: Strong Buy

  • Reply to

    PUMP , PUMP , PUMP Is all I hear on this board

    by harryz61 Jul 3, 2014 9:26 AM
    king_tuts_jewels king_tuts_jewels Jul 3, 2014 9:49 AM Flag

    A real fact !!!!!!!!
    New NeuVax grant from Defense Department.....
    Galena Biopharma Announces Department of Defense Grant for NeuVax(TM) (nelipepimut-S) Clinical Trial
    Phase 2 study in neoadjuvant, HER2 3+ Breast Cancer Patients to commence in 2014
    New study supports ongoing Phase 3 PRESENT study and Phase 2b in HER2 1+ and 2+ patients
    PORTLAND, Ore., April 28, 2014 (GLOBE NEWSWIRE) -- Galena Biopharma (Nasdaq:GALE), a biopharmaceutical company developing and commercializing innovative, targeted oncology treatments that address major unmet medical needs to advance cancer care, today announced the Department of Defense (DoD) will provide funding towards a new clinical trial with NeuVax to prevent breast cancer recurrence in high-risk HER2 3+ patients. The grant, a Breast Cancer Research Program (BCRP) Breakthrough Award, was obtained by Elizabeth A. Mittendorf, M.D., Associate Professor, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center who will oversee the investigator-sponsored trial. Galena will support the trial with study drug and funding and will have access to the research to support ongoing registrational studies.

    Sentiment: Strong Buy

  • Reply to

    PUMP , PUMP , PUMP Is all I hear on this board

    by harryz61 Jul 3, 2014 9:26 AM
    king_tuts_jewels king_tuts_jewels Jul 3, 2014 9:44 AM Flag

    This is a real fact!!!!!!!!!!!!!!
    The FDA gave Galena a Special Protocol Assessment (SPA) to NeuVax in PHase 3
    NeuVax™ (nelipepimut-S)

    NeuVax consists of the E75 peptide derived from HER2 combined with the immune adjuvant granulocyte macrophage colony stimulating factor (GM-CSF). Treatment with NeuVax stimulates cytotoxic (CD8+) T cells in a highly specific manner to target cells expressing any level of HER2. NeuVax is given as an intradermal injection once a month for six months, followed by a booster injection once every six months. Based on a successful Phase II trial, which achieved its primary endpoint of disease free survival (DFS), the Food and Drug Administration (FDA) granted NeuVax a Special Protocol Assessment (SPA) for a Phase III clinical trial in adjuvant therapy of women with low-to-intermediate (also known as HER2-Negative, not eligible for Herceptin) status. Less

    Sentiment: Strong Buy

  • king_tuts_jewels king_tuts_jewels Jul 3, 2014 9:09 AM Flag

    APPY was a. $140 stock not long ago. After two large reverse splits and not having much cash on hand...... Well you get the picture don't you? I wouldn't touch that piece of #$%$ if you paid me. Enough said!!

    Sentiment: Strong Buy

  • Reply to

    620K share trade at 4:00.00PM

    by king_tuts_jewels Jun 27, 2014 4:02 PM
    king_tuts_jewels king_tuts_jewels Jul 2, 2014 9:45 AM Flag

    MNKD at $15 this week? Be lucky to hit $11 again soon!

    Sentiment: Strong Buy

  • king_tuts_jewels king_tuts_jewels Jul 2, 2014 9:39 AM Flag

    Earnings will be out in five weeks. Strong ABSTRAL sales will be the catalyst to send GALE higher.

    Sentiment: Strong Buy

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