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PROLOR Biotech, Inc. Message Board

kinsp45 3 posts  |  Last Activity: Mar 3, 2016 9:03 AM Member since: Apr 15, 2009
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  • Reply to

    Pre-Market Up

    by kinsp45 Mar 3, 2016 8:19 AM
    kinsp45 kinsp45 Mar 3, 2016 9:03 AM Flag

    Thank you for the guidance. Very helpful

  • kinsp45 by kinsp45 Mar 3, 2016 8:19 AM Flag

    Could we see OPK over $10 this morning? Rayaldee will be huge - I reviewed the press release from OPKO on May 29th.

    Rayaldee is a first-in-class oral vitamin D prohormone treatment being developed for SHPT in patients with stage 3 or 4 CKD and vitamin D insufficiency. It has a proprietary modified-release formulation designed to gradually and reliably raise serum total 25-hydroxyvitamin D (prohormone) concentrations to targeted levels (at least 30 ng/mL) while avoiding upregulation of CYP24A1, a cytochrome P-450 enzyme which reduces the desired parathyroid hormone (PTH)-lowering efficacy. Gradual elevation of serum total 25-hydroxyvitamin D prevents excessive elevation of serum calcium and related vascular and renal calcification. Such side effects limit the value of current vitamin D hormone therapies. Rayaldee is expected to address the approximately 20 million patients in the U.S., and many more elsewhere, with stage 3 or 4 CKD, SHPT and vitamin D insufficiency.

  • Better buy now. OPKO will have some incredible news to discuss with analyst in NYC this summer.