Older people can convert IRA money into a Roth IRA only after they have taken out their Minimum Yearly Distribution from their IRA, if they are 70 and 1/2 years old or older.
It's the same deal for older people. But you have to remember that the extra income might push you into a higher tax bracket, and might trigger or increase the income tax on your Social Security benefits.
Two patients at Penn died of heart failure in 2013 after CAR-T therapy for cancer. The T-cells attacked a heart protein that was not present in the animals used in pre-clinical testing. Carl June in a recent interview said that an on-off switch is needed.
So move on. We're adults here and we take responsibility for our own actions. We don't need you hanging on and worrying about us.
I don't think you realize the significance of the stage 4 ovarian cancer patient's results. I've said this before, but not only did her spleen lesion disappear, but her greatly increased peritoneal fluid cleared. Increased peritoneal fluid is caused by metastatic tumor nodules that have seeded the peritoneal membranes. This means that those lesions have also regressed. This is unheard of in stage 4 ovarian cancer, and I believe it's why Dana Farber asked CTIX to write a paper on K.
I bought MEIP because of the top line data on phase 2 for AML.. The slide shows that the longer the treatment period, the greater the conversion to CR. So far, not one patient with a CR has relapsed. The investigator said he has never seen results like this in AML. I know AML is a smaller market than MDS, but I was surprised at the reaction to the MDS data. More complete data on phase 2 for AML is due in June. I doubled my holdings yesterday. Couldn't resist at 2 dollars a share. I think insurance companies might insist on treatment with pracinostat before they will pay for CAR-T therapy.
Not sure, but you can opt for all cash if ABBV's stock price is unacceptable.
Increased peritoneal fluid comes from metastatic tumor nodules that have seeded the peritoneal membranes. Reduction in fluid means that these lesions have also regressed. No wonder Dana Farber was excited about it.
Someone later mentions that the study is double blinded. Aren't all the patients receiving K? Would they give a stage 4 patient placebo?
I believe they split everything 50-50, including US sales. Their potential drug was so promising that J&J agreed to a deal like that.
The worrisome part is that they obviously know the p value but didn't release it. MEIP just released good results for AML and then shot themselves in the foot with a stock offering
The company said at one time that this drug will be tested for so many different conditions that they just don't have the resources to do it.
He is saying that in 26 patients, half of them showed regression in a lesion distant from the lesion that was injected. These are the "uninjected, unelectroporated" lesions, and is the basis for the claim that the treatment is showing a systemic response.
Cellceutix has announced that based on the phase 2 data, the phase 3 dose will be a single dose. A one dose treatment for a skin infection will not take 2 years to be ready for approval.
It's a measure of statistical significance. The highest acceptable value in a trial is .05, which means that the chance of the positive result being due to chance or coincidence was I out of 20. The lower the number, the more confident you can be that the positive result was actually due to the action of the drug. Some trials have p values of .001, meaning that the chance of the result being due to coincidence was 1 out of 1000.